Laurent Kremer
Laurent Kremer
Directeur de recherche INSERM
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Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug‐tolerant bacteria
AK Ojha, AD Baughn, D Sambandan, T Hsu, X Trivelli, Y Guerardel, ...
Molecular microbiology 69 (1), 164-174, 2008
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response
V Briken, SA Porcelli, GS Besra, L Kremer
Molecular microbiology 53 (2), 391-403, 2004
Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus
MD Johansen, JL Herrmann, L Kremer
Nature Reviews Microbiology 18 (7), 392-407, 2020
GroEL1: a dedicated chaperone involved in mycolic acid biosynthesis during biofilm formation in mycobacteria
A Ojha, M Anand, A Bhatt, L Kremer, WR Jacobs, GF Hatfull
Cell 123 (5), 861-873, 2005
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
C Vilchèze, F Wang, M Arai, MH Hazbón, R Colangeli, L Kremer, ...
Nature medicine 12 (9), 1027-1029, 2006
Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans
VJ Quesniaux, DM Nicolle, D Torres, L Kremer, Y Guérardel, J Nigou, ...
The Journal of Immunology 172 (7), 4425-4434, 2004
The methyl-branched fortifications of Mycobacterium tuberculosis
DE Minnikin, L Kremer, LG Dover, GS Besra
Chemistry & biology 9 (5), 545-553, 2002
Altered NADH/NAD+ Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria
C Vilcheze, TR Weisbrod, B Chen, L Kremer, MH Hazbón, F Wang, ...
Antimicrobial agents and chemotherapy 49 (2), 708-720, 2005
Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation
A Bernut, JL Herrmann, K Kissa, JF Dubremetz, JL Gaillard, G Lutfalla, ...
Proceedings of the National Academy of Sciences 111 (10), E943-E952, 2014
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites
M Yu, TRS Kumar, LJ Nkrumah, A Coppi, S Retzlaff, CD Li, BJ Kelly, ...
Cell host & microbe 4 (6), 567-578, 2008
Thiolactomycin and Related Analogues as Novel Anti-mycobacterial Agents Targeting KasA and KasB Condensing Enzymes inMycobacterium tuberculosis
L Kremer, JD Douglas, AR Baulard, C Morehouse, MR Guy, D Alland, ...
Journal of Biological Chemistry 275 (22), 16857-16864, 2000
The Mycobacterium tuberculosis FAS‐II condensing enzymes: their role in mycolic acid biosynthesis, acid‐fastness, pathogenesis and in future drug development
A Bhatt, V Molle, GS Besra, WR Jacobs Jr, L Kremer
Molecular microbiology 64 (6), 1442-1454, 2007
Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis
MH Larsen, C Vilchèze, L Kremer, GS Besra, L Parsons, M Salfinger, ...
Molecular microbiology 46 (2), 453-466, 2002
Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice
A Bhatt, N Fujiwara, K Bhatt, SS Gurcha, L Kremer, B Chen, J Chan, ...
Proceedings of the National Academy of Sciences 104 (12), 5157-5162, 2007
Identification and substrate specificity of β-ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis
KH Choi, L Kremer, GS Besra, CO Rock
Journal of Biological Chemistry 275 (36), 28201-28207, 2000
Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens
F Biet, C Locht, L Kremer
Journal of molecular medicine 80, 147-162, 2002
Mycobacterium tuberculosis Lipomannan Induces Apoptosis and Interleukin-12 Production in Macrophages
DN Dao, L Kremer, Y Guérardel, A Molano, WR Jacobs Jr, SA Porcelli, ...
Infection and immunity 72 (4), 2067-2074, 2004
Division and cell envelope regulation by Ser/Thr phosphorylation: Mycobacterium shows the way
V Molle, L Kremer
Molecular microbiology 75 (5), 1064-1077, 2010
Galactan biosynthesis in Mycobacterium tuberculosis: identification of a bifunctional UDP-galactofuranosyltransferase
L Kremer, LG Dover, C Morehouse, P Hitchin, M Everett, HR Morris, A Dell, ...
Journal of Biological Chemistry 276 (28), 26430-26440, 2001
Green fluorescent protein as a new expression marker in mycobacteria
L Kremer, A Baulard, J Estaquier, O Poulain‐Godefroy, C Locht
Molecular Microbiology 17 (5), 913-922, 1995
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