Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug‐tolerant bacteria AK Ojha, AD Baughn, D Sambandan, T Hsu, X Trivelli, Y Guerardel, ... Molecular microbiology 69 (1), 164-174, 2008 | 622 | 2008 |
Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus MD Johansen, JL Herrmann, L Kremer Nature Reviews Microbiology 18 (7), 392-407, 2020 | 621 | 2020 |
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response V Briken, SA Porcelli, GS Besra, L Kremer Molecular microbiology 53 (2), 391-403, 2004 | 593 | 2004 |
GroEL1: a dedicated chaperone involved in mycolic acid biosynthesis during biofilm formation in mycobacteria A Ojha, M Anand, A Bhatt, L Kremer, WR Jacobs, GF Hatfull Cell 123 (5), 861-873, 2005 | 479 | 2005 |
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid C Vilchèze, F Wang, M Arai, MH Hazbón, R Colangeli, L Kremer, ... Nature medicine 12 (9), 1027-1029, 2006 | 408 | 2006 |
Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans VJ Quesniaux, DM Nicolle, D Torres, L Kremer, Y Guérardel, J Nigou, ... The Journal of Immunology 172 (7), 4425-4434, 2004 | 370 | 2004 |
Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation A Bernut, JL Herrmann, K Kissa, JF Dubremetz, JL Gaillard, G Lutfalla, ... Proceedings of the National Academy of Sciences 111 (10), E943-E952, 2014 | 358 | 2014 |
Altered NADH/NAD+ Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria C Vilcheze, TR Weisbrod, B Chen, L Kremer, MH Hazbón, F Wang, ... Antimicrobial agents and chemotherapy 49 (2), 708-720, 2005 | 356 | 2005 |
The methyl-branched fortifications of Mycobacterium tuberculosis DE Minnikin, L Kremer, LG Dover, GS Besra Chemistry & biology 9 (5), 545-553, 2002 | 349 | 2002 |
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites M Yu, TRS Kumar, LJ Nkrumah, A Coppi, S Retzlaff, CD Li, BJ Kelly, ... Cell host & microbe 4 (6), 567-578, 2008 | 338 | 2008 |
Thiolactomycin and Related Analogues as Novel Anti-mycobacterial Agents Targeting KasA and KasB Condensing Enzymes inMycobacterium tuberculosis L Kremer, JD Douglas, AR Baulard, C Morehouse, MR Guy, D Alland, ... Journal of Biological Chemistry 275 (22), 16857-16864, 2000 | 329 | 2000 |
The Mycobacterium tuberculosis FAS‐II condensing enzymes: their role in mycolic acid biosynthesis, acid‐fastness, pathogenesis and in future drug development A Bhatt, V Molle, GS Besra, WR Jacobs Jr, L Kremer Molecular microbiology 64 (6), 1442-1454, 2007 | 293 | 2007 |
Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis MH Larsen, C Vilchèze, L Kremer, GS Besra, L Parsons, M Salfinger, ... Molecular microbiology 46 (2), 453-466, 2002 | 292 | 2002 |
Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice A Bhatt, N Fujiwara, K Bhatt, SS Gurcha, L Kremer, B Chen, J Chan, ... Proceedings of the National Academy of Sciences 104 (12), 5157-5162, 2007 | 264 | 2007 |
Identification and substrate specificity of β-ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis KH Choi, L Kremer, GS Besra, CO Rock Journal of Biological Chemistry 275 (36), 28201-28207, 2000 | 255 | 2000 |
Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens F Biet, C Locht, L Kremer Journal of molecular medicine 80, 147-162, 2002 | 247 | 2002 |
Mycobacterium tuberculosis Lipomannan Induces Apoptosis and Interleukin-12 Production in Macrophages DN Dao, L Kremer, Y Guérardel, A Molano, WR Jacobs Jr, SA Porcelli, ... Infection and immunity 72 (4), 2067-2074, 2004 | 238 | 2004 |
Division and cell envelope regulation by Ser/Thr phosphorylation: Mycobacterium shows the way V Molle, L Kremer Molecular microbiology 75 (5), 1064-1077, 2010 | 217 | 2010 |
Galactan biosynthesis in Mycobacterium tuberculosis: identification of a bifunctional UDP-galactofuranosyltransferase L Kremer, LG Dover, C Morehouse, P Hitchin, M Everett, HR Morris, A Dell, ... Journal of Biological Chemistry 276 (28), 26430-26440, 2001 | 211 | 2001 |
Lipomannans, but not lipoarabinomannans, purified from Mycobacterium chelonae and Mycobacterium kansasii induce TNF-α and IL-8 secretion by a CD14-Toll-like receptor 2 … C Vignal, Y Guérardel, L Kremer, M Masson, D Legrand, J Mazurier, ... The Journal of immunology 171 (4), 2014-2023, 2003 | 190 | 2003 |