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Bryan C. Quach
Bryan C. Quach
Bioinformatics Scientist, RTI International
Dirección de correo verificada de rti.org - Página principal
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Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
BC Quach, MJ Bray, NC Gaddis, M Liu, T Palviainen, CC Minica, S Zellers, ...
Nature communications 11 (1), 5562, 2020
992020
DeFCoM: analysis and modeling of transcription factor binding sites using a motif-centric genomic footprinter
B Quach, TS Furey
Bioinformatics 33 (7), 956-963, 2017
402017
Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation
GR Keele, BC Quach, JW Israel, GA Chappell, L Lewis, A Safi, JM Simon, ...
PLoS genetics 16 (1), e1008537, 2020
372020
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond
N Gaddis, R Mathur, J Marks, L Zhou, B Quach, A Waldrop, O Levran, ...
Scientific reports 12 (1), 16873, 2022
342022
Correcting nucleotide-specific biases in high-throughput sequencing data
JR Wang, B Quach, TS Furey
BMC bioinformatics 18, 1-10, 2017
252017
Epigenome‐wide analysis uncovers a blood‐based DNA methylation biomarker of lifetime cannabis use
CA Markunas, DB Hancock, Z Xu, BC Quach, F Fang, DP Sandler, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2019
212019
Genome-wide DNA methylation differences in nucleus accumbens of smokers vs. nonsmokers
CA Markunas, SA Semick, BC Quach, R Tao, A Deep-Soboslay, ...
Neuropsychopharmacology 46 (3), 554-560, 2021
202021
Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits
NYA Sey, B Hu, M Iskhakova, S Lee, H Sun, N Shokrian, G Ben Hutta, ...
Molecular psychiatry 27 (7), 3085-3094, 2022
192022
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
F Chen, X Wang, SK Jang, BC Quach, JD Weissenkampen, ...
Nature genetics 55 (2), 291-300, 2023
182023
Strategies for cellular deconvolution in human brain RN A sequencing data [version 1; peer review: awaiting peer
OA Sosina, MN Tran, KR Maynard, R Tao, MA Taub, K Martinowich, ...
13*2021
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose
O Corradin, R Sallari, AT Hoang, BS Kassim, G Ben Hutta, L Cuoto, ...
Molecular psychiatry 27 (4), 2158-2170, 2022
112022
Integration of evidence across human and model organism studies: A meeting report
RHC Palmer, EC Johnson, H Won, R Polimanti, M Kapoor, A Chitre, ...
Genes, Brain and Behavior 20 (6), e12738, 2021
102021
The evolution and putative function of phosducin-like proteins in the malaria parasite Plasmodium
C Putonti, B Quach, RL Kooistra, SM Kanzok
Infection, Genetics and Evolution 13, 49-55, 2013
32013
Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive …
A Moore, JA Marks, BC Quach, Y Guo, LJ Bierut, NC Gaddis, DB Hancock, ...
Communications Biology 6 (1), 1199, 2023
2*2023
Identifying novel gene dysregulation associated with opioid overdose death: A meta-analysis of differential gene expression in human prefrontal cortex
JK Carter, BC Quach, C Willis, MS Minto, DB Hancock, J Montalvo-Ortiz, ...
medRxiv, 2024
12024
Identifying compounds to treat opiate use disorder by leveraging multi-omic data integration and multiple drug repurposing databases.
JK Stratford, MU Carnes, C Willis, MS Minto, L Elnimeiry, R Mathur, ...
medRxiv, 2024.01. 17.24301329, 2024
12024
Gene expression differences associated with alcohol use disorder in human brain
C Willis, JD White, MS Minto, BC Quach, S Han, R Tao, JH Shin, ...
medRxiv, 2024.01. 20.24301386, 2024
2024
Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex
JD White, MS Minto, C Willis, BC Quach, S Han, R Tao, A Deep-Soboslay, ...
medRxiv, 2024.01. 17.23300238, 2024
2024
Gene dysregulation among virally suppressed people living with HIV links to non-AIDS defining cancer pathways
BC Quach, E Earley, L Zhou, C Willis, JA Marks, JK Stratford, F Fang, ...
medRxiv, 2024.01. 03.24300792, 2024
2024
Multi-omic network analysis identifies dysregulated neurobiological pathways in opioid addiction
KA Sullivan, D Kainer, M Lane, M Cashman, JI Miller, MR Garvin, ...
medRxiv, 2024.01. 04.24300831, 2024
2024
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Artículos 1–20