Benjamin D Humphreys
Benjamin D Humphreys
Professor of Medicine, Washington University
Verified email at - Homepage
Cited by
Cited by
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
BD Humphreys, SL Lin, A Kobayashi, TE Hudson, BT Nowlin, ...
The American journal of pathology 176 (1), 85-97, 2010
Intrinsic epithelial cells repair the kidney after injury
BD Humphreys, MT Valerius, A Kobayashi, JW Mugford, S Soeung, ...
Cell stem cell 2 (3), 284-291, 2008
Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
T Ichimura, EJP Asseldonk, BD Humphreys, L Gunaratnam, JS Duffield, ...
The Journal of clinical investigation 118 (5), 1657-1668, 2008
Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis
R Kramann, RK Schneider, DP DiRocco, F Machado, S Fleig, PA Bondzie, ...
Cell stem cell 16 (1), 51-66, 2015
Mechanisms of renal fibrosis
BD Humphreys
Annual review of physiology 80, 309-326, 2018
Advantages of single-nucleus over single-cell RNA sequencing of adult kidney: rare cell types and novel cell states revealed in fibrosis
H Wu, Y Kirita, EL Donnelly, BD Humphreys
Journal of the American Society of Nephrology 30 (1), 23-32, 2019
Comparative analysis and refinement of human PSC-derived kidney organoid differentiation with single-cell transcriptomics
H Wu, K Uchimura, EL Donnelly, Y Kirita, SA Morris, BD Humphreys
Cell stem cell 23 (6), 869-881. e8, 2018
Differentiated kidney epithelial cells repair injured proximal tubule
T Kusaba, M Lalli, R Kramann, A Kobayashi, BD Humphreys
Proceedings of the National Academy of Sciences 111 (4), 1527-1532, 2014
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis
I Grgic, G Campanholle, V Bijol, C Wang, VS Sabbisetti, T Ichimura, ...
Kidney international 82 (2), 172-183, 2012
Repair of injured proximal tubule does not involve specialized progenitors
BD Humphreys, S Czerniak, DP DiRocco, W Hasnain, R Cheema, ...
Proceedings of the National Academy of Sciences 108 (22), 9226-9231, 2011
Mesenchymal stem cells in acute kidney injury
BD Humphreys, JV Bonventre
Annu. Rev. Med. 59, 311-325, 2008
Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis
BD Humphreys, F Xu, V Sabbisetti, I Grgic, SM Naini, N Wang, G Chen, ...
The Journal of clinical investigation 123 (9), 4023-4035, 2013
Mesenchymal stem cells in fibrotic disease
E El Agha, R Kramann, RK Schneider, X Li, W Seeger, BD Humphreys, ...
Cell stem cell 21 (2), 166-177, 2017
The single-cell transcriptomic landscape of early human diabetic nephropathy
PC Wilson, H Wu, Y Kirita, K Uchimura, N Ledru, HG Rennke, PA Welling, ...
Proceedings of the National Academy of Sciences 116 (39), 19619-19625, 2019
Cediranib, an oral inhibitor of vascular endothelial growth factor receptor kinases, is an active drug in recurrent epithelial ovarian, fallopian tube, and peritoneal cancer
UA Matulonis, S Berlin, P Ivy, K Tyburski, C Krasner, C Zarwan, ...
Journal of clinical oncology 27 (33), 5601, 2009
Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury
Y Kirita, H Wu, K Uchimura, PC Wilson, BD Humphreys
Proceedings of the National Academy of Sciences 117 (27), 15874-15883, 2020
Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response
H Wu, AF Malone, EL Donnelly, Y Kirita, K Uchimura, SM Ramakrishnan, ...
Journal of the American Society of Nephrology 29 (8), 2069-2080, 2018
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease
R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ...
Cell stem cell 19 (5), 628-642, 2016
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor
BD Humphreys, J Rice, SB Kertesy, GR Dubyak
Journal of Biological Chemistry 275 (35), 26792-26798, 2000
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
Y Muto, PC Wilson, N Ledru, H Wu, H Dimke, SS Waikar, BD Humphreys
Nature communications 12 (1), 2190, 2021
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