Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae. DE Briles, M Nahm, K Schroer, J Davie, P Baker, J Kearney, R Barletta The Journal of experimental medicine 153 (3), 694-705, 1981 | 600 | 1981 |
Subclass restriction of murine anti-carbohydrate antibodies RM Perlmutter, D Hansburg, DE Briles, RA Nicolotti, JM David The Journal of Immunology 121 (2), 566-572, 1978 | 552 | 1978 |
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae AM Berry, J Yother, DE Briles, D Hansman, JC Paton Infection and immunity 57 (7), 2037-2042, 1989 | 450 | 1989 |
Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae SK Hollingshead, R Becker, DE Briles Infection and immunity 68 (10), 5889-5900, 2000 | 433 | 2000 |
Pneumococcal Surface Protein A Inhibits Complement Activation by Streptococcus pneumoniae AHT Tu, RL Fulgham, MA McCrory, DE Briles, AJ Szalai Infection and immunity 67 (9), 4720-4724, 1999 | 428 | 1999 |
Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae DE Briles, E Ades, JC Paton, JS Sampson, GM Carlone, RC Huebner, ... Infection and immunity 68 (2), 796-800, 2000 | 389 | 2000 |
Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae. DE Briles, C Forman, S Hudak, JL Claflin The Journal of experimental medicine 156 (4), 1177-1185, 1982 | 388 | 1982 |
Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae MJ Crain, WD Waltman 2nd, JS Turner, J Yother, DF Talkington, ... Infection and immunity 58 (10), 3293-3299, 1990 | 362 | 1990 |
Basophils enhance immunological memory responses A Denzel, UA Maus, MR Gomez, C Moll, M Niedermeier, C Winter, ... Nature immunology 9 (7), 733-742, 2008 | 361 | 2008 |
Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae DE Briles, MJ Crain, BM Gray, C Forman, J Yother Infection and immunity 60 (1), 111-116, 1992 | 351 | 1992 |
The pspC Gene of Streptococcus pneumoniae Encodes a Polymorphic Protein, PspC, Which Elicits Cross-Reactive Antibodies to PspA and Provides Immunity to … A Brooks-Walter, DE Briles, SK Hollingshead Infection and immunity 67 (12), 6533-6542, 1999 | 331 | 1999 |
PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type LS McDANIEL, JS Sheffield, P Delucchi, DE Briles Infection and immunity 59 (1), 222-228, 1991 | 313 | 1991 |
Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae HY Wu, MH Nahm, Y Guo, MW Russell, DE Briles Journal of Infectious Diseases 175 (4), 839-846, 1997 | 304 | 1997 |
PspA Protects Streptococcus pneumoniae from Killing by Apolactoferrin, and Antibody to PspA Enhances Killing of Pneumococci by Apolactoferrin M Shaper, SK Hollingshead, WH Benjamin Jr, DE Briles Infection and immunity 72 (9), 5031-5040, 2004 | 295 | 2004 |
Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae … DE Briles, SK Hollingshead, J King, A Swift, PA Braun, MK Park, ... The Journal of infectious diseases 182 (6), 1694-1701, 2000 | 292 | 2000 |
Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis J Yother, DE Briles Journal of bacteriology 174 (2), 601-609, 1992 | 287 | 1992 |
Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice. AJ Szalai, DE Briles, JE Volanakis Journal of immunology (Baltimore, Md.: 1950) 155 (5), 2557-2563, 1995 | 286 | 1995 |
Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae DE Briles, SK Hollingshead, JC Paton, EW Ades, L Novak, FW van Ginkel, ... The Journal of infectious diseases 188 (3), 339-348, 2003 | 285 | 2003 |
Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA). LS McDANIEL, J Yother, M Vijayakumar, L McGARRY, WR Guild, ... The Journal of experimental medicine 165 (2), 381-394, 1987 | 278 | 1987 |
Development of a Vaccine against Invasive Pneumococcal Disease Based on Combinations of Virulence Proteins of Streptococcus pneumoniae AD Ogunniyi, M Grabowicz, DE Briles, J Cook, JC Paton Infection and immunity 75 (1), 350-357, 2007 | 276 | 2007 |