Philip Howe
Philip Howe
Department of Biochemistry Medical University of South Carolina
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TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
BA Hocevar, TL Brown, PH Howe
The EMBO journal 18 (5), 1345-1356, 1999
Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles
A Chaudhury, P Chander, PH Howe
Rna 16 (8), 1449-1462, 2010
TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI
A Chaudhury, GS Hussey, PS Ray, G Jin, PL Fox, PH Howe
Nature cell biology 12 (3), 286-293, 2010
The adaptor molecule Disabled‐2 links the transforming growth factor β receptors to the Smad pathway
BA Hocevar, A Smine, XX Xu, PH Howe
The EMBO journal, 2001
Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function
XJ Qi, GM Wildey, PH Howe
Journal of Biological Chemistry 281 (2), 813-823, 2006
A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression
S Grelet, LA Link, B Howley, C Obellianne, V Palanisamy, VK Gangaraju, ...
Nature cell biology 19 (9), 1105-1115, 2017
Identification of an mRNP complex regulating tumorigenesis at the translational elongation step
GS Hussey, A Chaudhury, AE Dawson, DJ Lindner, CR Knudsen, ...
Molecular cell 41 (4), 419-431, 2011
Transforming growth factor β1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest
PH Howe, G Draetta, EB Leof
Molecular and cellular biology, 1991
TGF-beta suppresses IFN-gamma induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression.
YJ Lee, Y Han, HT Lu, V Nguyen, H Qin, PH Howe, BA Hocevar, JM Boss, ...
Journal of immunology (Baltimore, Md.: 1950) 158 (5), 2065-2075, 1997
Transforming growth factor β (TGFβ)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cells
KB Reddy, G Jin, MC Karode, JAK Harmony, PH Howe
Biochemistry 35 (19), 6157-6163, 1996
Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells
A Mal, RYC Poon, PH Howe, H Toyoshima, T Hunter, ML Harter
Nature 380 (6571), 262-265, 1996
Oxidized low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells: evidence for release of fibroblast growth factor-2
YC Chai, PH Howe, PE DiCorleto, GM Chisolm
Journal of Biological Chemistry 271 (30), 17791-17797, 1996
Disabled-2 (Dab2) is required for transforming growth factor β-induced epithelial to mesenchymal transition (EMT)
C Prunier, PH Howe
Journal of Biological Chemistry 280 (17), 17540-17548, 2005
Regulation of the Wnt signaling pathway by disabled‐2 (Dab2)
BA Hocevar, F Mou, JL Rennolds, SM Morris, JA Cooper, PH Howe
The EMBO journal, 2003
Wnt signaling: physiology and pathology
C Prunier, BA Hocevar, PH Howe
Growth Factors 22 (3), 141-150, 2004
Myosin II isoform switching mediates invasiveness after TGF-β–induced epithelial–mesenchymal transition
JR Beach, GS Hussey, TE Miller, A Chaudhury, P Patel, J Monslow, ...
Proceedings of the National Academy of Sciences 108 (44), 17991-17996, 2011
Regulation of clusterin gene expression by transforming growth factor β
G Jin, PH Howe
Journal of Biological Chemistry 272 (42), 26620-26626, 1997
Smad3 potentiates transforming growth factor β (TGFβ)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes
GM Wildey, S Patil, PH Howe
Journal of Biological Chemistry 278 (20), 18069-18077, 2003
Secreted transforming growth factor β2 activates NF-κB, blocks apoptosis, and is essential for the survival of some tumor cells
T Lu, LG Burdelya, SM Swiatkowski, AD Boiko, PH Howe, GR Stark, ...
Proceedings of the National Academy of Sciences 101 (18), 7112-7117, 2004
Disabled-2 (Dab2) Mediates Transforming Growth Factor β (TGFβ)-stimulated Fibronectin Synthesis through TGFβ-activatedKinase 1 and Activation of the JNKPathway
BA Hocevar, C Prunier, PH Howe
Journal of Biological Chemistry 280 (27), 25920-25927, 2005
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