| A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis BH Ahn, HS Kim, S Song, IH Lee, J Liu, A Vassilopoulos, CX Deng, ... Proceedings of the National Academy of Sciences 105 (38), 14447-14452, 2008 | 1503 | 2008 |
| SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress HS Kim, K Patel, K Muldoon-Jacobs, KS Bisht, N Aykin-Burns, ... Cancer cell 17 (1), 41-52, 2010 | 928 | 2010 |
| SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity HS Kim, A Vassilopoulos, RH Wang, T Lahusen, Z Xiao, X Xu, C Li, ... Cancer cell 20 (4), 487-499, 2011 | 613 | 2011 |
| Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis HS Kim, C Xiao, RH Wang, T Lahusen, X Xu, A Vassilopoulos, ... Cell metabolism 12 (3), 224-236, 2010 | 548 | 2010 |
| Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis RH Wang, Y Zheng, HS Kim, X Xu, L Cao, T Lahusen, MH Lee, C Xiao, ... Molecular cell 32 (1), 11-20, 2008 | 430 | 2008 |
| SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells O Ozden, SH Park, BA Wagner, HY Song, Y Zhu, A Vassilopoulos, B Jung, ... Free Radical Biology and Medicine 76, 163-172, 2014 | 201 | 2014 |
| SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient-and exercise-induced stress A Vassilopoulos, JD Pennington, T Andresson, DM Rees, AD Bosley, ... Antioxidants & redox signaling 21 (4), 551-564, 2014 | 201 | 2014 |
| Sirtuins at the crossroads of stemness, aging, and cancer C O'Callaghan, A Vassilopoulos Aging cell 16 (6), 1208-1218, 2017 | 195 | 2017 |
| The human sirtuin family: evolutionary divergences and functions A Vassilopoulos, KS Fritz, DR Petersen, D Gius Human genomics 5, 1-12, 2011 | 192 | 2011 |
| Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis R Tao, A Vassilopoulos, L Parisiadou, Y Yan, D Gius Antioxidants & redox signaling 20 (10), 1646-1654, 2014 | 191 | 2014 |
| Histone H2AX is integral to hypoxia-driven neovascularization M Economopoulou, HF Langer, A Celeste, VV Orlova, EY Choi, M Ma, ... Nature medicine 15 (5), 553-558, 2009 | 151 | 2009 |
| Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2 X Yang, SH Park, HC Chang, JS Shapiro, A Vassilopoulos, KT Sawicki, ... The Journal of clinical investigation 127 (4), 1505-1516, 2017 | 123 | 2017 |
| SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth SH Park, O Ozden, G Liu, HY Song, Y Zhu, Y Yan, X Zou, HJ Kang, ... Cancer research 76 (13), 3802-3812, 2016 | 121 | 2016 |
| SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis SH Park, Y Zhu, O Ozden, HS Kim, H Jiang, CX Deng, D Gius, ... Translational cancer research 1 (1), 15, 2012 | 115 | 2012 |
| Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells A Vassilopoulos, RH Wang, C Petrovas, D Ambrozak, R Koup, CX Deng International journal of biological sciences 4 (3), 133, 2008 | 113 | 2008 |
| BRCA1 affects global DNA methylation through regulation of DNMT1 V Shukla, X Coumoul, T Lahusen, RH Wang, X Xu, A Vassilopoulos, ... Cell research 20 (11), 1201-1215, 2010 | 109 | 2010 |
| SIRT2 directs the replication stress response through CDK9 deacetylation H Zhang, SH Park, BG Pantazides, O Karpiuk, MD Warren, CW Hardy, ... Proceedings of the National Academy of Sciences 110 (33), 13546-13551, 2013 | 107 | 2013 |
| A critical role of CD29 and CD49f in mediating metastasis for cancer-initiating cells isolated from a Brca1-associated mouse model of breast cancer A Vassilopoulos, C Chisholm, T Lahusen, H Zheng, CX Deng Oncogene 33 (47), 5477-5482, 2014 | 89 | 2014 |
| SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis Y Zhu, Y Yan, DR Principe, X Zou, A Vassilopoulos, D Gius Cancer & metabolism 2, 1-11, 2014 | 80 | 2014 |
| Metabolic regulation of Sirtuins upon fasting and the implication for cancer Y Zhu, Y Yan, DR Gius, A Vassilopoulos Current opinion in oncology 25 (6), 630-636, 2013 | 74 | 2013 |
