Novel Pentameric Thiophene Derivatives for in Vitro and in Vivo Optical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses A Åslund, CJ Sigurdson, T Klingstedt, S Grathwohl, T Bolmont, ... ACS chemical biology 4 (8), 673-684, 2009 | 380 | 2009 |
Delivering the power of nanomedicine to patients today M Germain, F Caputo, S Metcalfe, G Tosi, K Spring, AKO Åslund, A Pottier, ... Journal of Controlled Release 326, 164-171, 2020 | 335 | 2020 |
Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates T Klingstedt, A Åslund, RA Simon, LBG Johansson, JJ Mason, S Nyström, ... Organic & biomolecular chemistry 9 (24), 8356-8370, 2011 | 225 | 2011 |
Imaging distinct conformational states of amyloid-β fibrils in Alzheimer’s disease using novel luminescent probes KPR Nilsson, A Åslund, I Berg, S Nyström, P Konradsson, A Herland, ... ACS chemical biology 2 (8), 553-560, 2007 | 225 | 2007 |
Seeded strain‐like transmission of β‐amyloid morphotypes in APP transgenic mice G Heilbronner, YS Eisele, F Langer, SA Kaeser, R Novotny, ... EMBO reports 14 (11), 1017-1022, 2013 | 165 | 2013 |
Structure-based drug design identifies polythiophenes as antiprion compounds US Herrmann, AK Schütz, H Shirani, D Huang, D Saban, M Nuvolone, ... Science translational medicine 7 (299), 299ra123-299ra123, 2015 | 142 | 2015 |
Iron-catalyzed polymerization of alkoxysulfonate-functionalized 3, 4-ethylenedioxythiophene gives water-soluble poly (3, 4-ethylenedioxythiophene) of high conductivity RH Karlsson, A Herland, M Hamedi, JA Wigenius, A Åslund, X Liu, ... Chemistry of Materials 21 (9), 1815-1821, 2009 | 126 | 2009 |
The structural basis for optimal performance of oligothiophene‐based fluorescent amyloid ligands: Conformational flexibility is essential for spectral assignment of a diversity … T Klingstedt, H Shirani, KOA Åslund, NJ Cairns, CJ Sigurdson, M Goedert, ... Chemistry–A European Journal 19 (31), 10179-10192, 2013 | 125 | 2013 |
A fluorescent pentameric thiophene derivative detects in vitro-formed prefibrillar protein aggregates P Hammarstrom, R Simon, S Nystrom, P Konradsson, A Åslund, ... Biochemistry 49 (32), 6838-6845, 2010 | 120 | 2010 |
Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy KPR Nilsson, K Ikenberg, A Åslund, S Fransson, P Konradsson, C Röcken, ... The American journal of pathology 176 (2), 563-574, 2010 | 119 | 2010 |
Labeling nanoparticles: Dye leakage and altered cellular uptake S Snipstad, S Hak, H Baghirov, E Sulheim, Ý Mørch, S Lélu, ... Cytometry Part A 91 (8), 760-766, 2017 | 111 | 2017 |
Studies of luminescent conjugated polythiophene derivatives: enhanced spectral discrimination of protein conformational states A Åslund, A Herland, P Hammarström, KPR Nilsson, BH Jonsson, ... Bioconjugate chemistry 18 (6), 1860-1868, 2007 | 111 | 2007 |
Cellular uptake and intracellular degradation of poly (alkyl cyanoacrylate) nanoparticles E Sulheim, H Baghirov, E von Haartman, A Bøe, AKO Åslund, Y Mørch, ... Journal of nanobiotechnology 14, 1-14, 2016 | 106 | 2016 |
Nanoparticle‐stabilized microbubbles for multimodal imaging and drug delivery Ý Mørch, R Hansen, S Berg, AKO Åslund, WR Glomm, S Eggen, ... Contrast media & molecular imaging 10 (5), 356-366, 2015 | 82 | 2015 |
Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates I Margalith, C Suter, B Ballmer, P Schwarz, C Tiberi, T Sonati, J Falsig, ... Journal of Biological Chemistry 287 (23), 18872-18887, 2012 | 80 | 2012 |
Nanoparticle delivery to the brain—By focused ultrasound and self-assembled nanoparticle-stabilized microbubbles AKO Åslund, S Berg, S Hak, Ý Mørch, SH Torp, A Sandvig, M Widerøe, ... Journal of Controlled Release 220, 287-294, 2015 | 73 | 2015 |
Contact-mediated intracellular delivery of hydrophobic drugs from polymeric nanoparticles S Snipstad, S Westrøm, Y Mørch, M Afadzi, AKO Åslund, ... Cancer nanotechnology 5, 1-18, 2014 | 63 | 2014 |
Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model H Baghirov, S Snipstad, E Sulheim, S Berg, R Hansen, F Thorsen, ... PLoS One 13 (1), e0191102, 2018 | 52 | 2018 |
Fluorescent oligo and poly-thiophenes and their utilization for recording biological events of diverse origin—when organic chemistry meets biology A Åslund, KPR Nilsson, P Konradsson Journal of chemical biology 2, 161-175, 2009 | 48 | 2009 |
Pentameric Thiophene‐Based Ligands that Spectrally Discriminate Amyloid‐β and Tau Aggregates Display Distinct Solvatochromism and Viscosity‐Induced Spectral Shifts RA Simon, H Shirani, KOA Åslund, M Bäck, V Haroutunian, S Gandy, ... Chemistry–A European Journal 20 (39), 12537-12543, 2014 | 39 | 2014 |