Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma M Feng, W Gao, R Wang, W Chen, YG Man, WD Figg, XW Wang, ... Proceedings of the National Academy of Sciences 110 (12), E1083-E1091, 2013 | 209 | 2013 |
Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican‐3 for liver cancer therapy W Gao, H Kim, M Feng, Y Phung, CP Xavier, JS Rubin, M Ho Hepatology 60 (2), 576-587, 2014 | 169 | 2014 |
Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis W Gao, Z Tang, YF Zhang, M Feng, M Qian, DS Dimitrov, M Ho Nature communications 6 (1), 6536, 2015 | 149 | 2015 |
Glypican-3 antibodies: a new therapeutic target for liver cancer M Feng, M Ho FEBS letters 588 (2), 377-382, 2014 | 145 | 2014 |
Persistent polyfunctional chimeric antigen receptor T cells that target glypican 3 eliminate orthotopic hepatocellular carcinomas in mice D Li, N Li, YF Zhang, H Fu, M Feng, D Schneider, L Su, X Wu, J Zhou, ... Gastroenterology 158 (8), 2250-2265. e20, 2020 | 136 | 2020 |
A frizzled‐like cysteine‐rich domain in Glypican‐3 mediates Wnt binding and regulates hepatocellular carcinoma tumor growth in mice N Li, L Wei, X Liu, H Bai, Y Ye, D Li, N Li, U Baxa, Q Wang, L Lv, Y Chen, ... Hepatology 70 (4), 1231-1245, 2019 | 93 | 2019 |
Construction and next-generation sequencing analysis of a large phage-displayed VNAR single-domain antibody library from six naïve nurse sharks M Feng, H Bian, X Wu, T Fu, Y Fu, J Hong, BD Fleming, MF Flajnik, M Ho Antibody therapeutics 2 (1), 1-11, 2019 | 84 | 2019 |
Glypican-3 targeted human heavy chain antibody as a drug carrier for hepatocellular carcinoma therapy H Hanaoka, T Nagaya, K Sato, Y Nakamura, R Watanabe, T Harada, ... Molecular pharmaceutics 12 (6), 2151-2157, 2015 | 75 | 2015 |
A novel high‐affinity human monoclonal antibody to mesothelin M Ho, M Feng, RJ Fisher, C Rader, I Pastan International Journal of Cancer 128 (9), 2020-2030, 2011 | 73 | 2011 |
Mesothelin as a potential therapeutic target in human cholangiocarcinoma L Yu, M Feng, H Kim, Y Phung, DE Kleiner, GJ Gores, M Qian, XW Wang, ... Journal of Cancer 1, 141, 2010 | 68 | 2010 |
The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy X Xiang, Y Phung, M Feng, K Nagashima, J Zhang, VC Broaddus, ... PLoS One 6 (1), e14640, 2011 | 55 | 2011 |
Combined DLL3-targeted bispecific antibody with PD-1 inhibition is efficient to suppress small cell lung cancer growth X Chen, N Amar, Y Zhu, C Wang, C Xia, X Yang, D Wu, M Feng Journal for immunotherapy of cancer 8 (1), 2020 | 54 | 2020 |
A human single-domain antibody elicits potent antitumor activity by targeting an epitope in mesothelin close to the cancer cell surface Z Tang, M Feng, W Gao, Y Phung, W Chen, A Chaudhary, BS Croix, ... Molecular cancer therapeutics 12 (4), 416-426, 2013 | 53 | 2013 |
HN125: a novel immunoadhesin targeting MUC16 with potential for cancer therapy X Xiang, M Feng, M Felder, JP Connor, Y Man, MS Patankar, M Ho Journal of Cancer 2, 280, 2011 | 47 | 2011 |
An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development Z Wang, Z Wu, H Wang, R Feng, G Wang, M Li, SY Wang, X Chen, Y Su, ... Cell 186 (20), 4454-4471. e19, 2023 | 46 | 2023 |
Recombinant soluble glypican 3 protein inhibits the growth of hepatocellular carcinoma in vitro M Feng, H Kim, Y Phung, M Ho International journal of cancer. Journal international du cancer 128 (9), 2246, 2011 | 46 | 2011 |
Construction of an immunotoxin, HN3-mPE24, targeting glypican-3 for liver cancer therapy C Wang, W Gao, M Feng, I Pastan, M Ho Oncotarget 8 (20), 32450, 2017 | 41 | 2017 |
Mesothelin antibodies and methods for eliciting potent antitumor activity M Ho, IH Pastan, DS Dimitrov, Z Tang, M Feng, W Gao US Patent 9,416,190, 2016 | 41 | 2016 |
Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells P Meng, YF Zhang, W Zhang, X Chen, T Xu, S Hu, X Liang, M Feng, ... Scientific reports 11 (1), 40, 2021 | 36 | 2021 |
In vivo imaging of human malignant mesothelioma grown orthotopically in the peritoneal cavity of nude mice M Feng, J Zhang, M Anver, R Hassan, M Ho Journal of Cancer 2, 123, 2011 | 29 | 2011 |