| Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by β-amyloid peptides via p38 mitogen-activated protein kinase pathway PM Canas, LO Porciúncula, GMA Cunha, CG Silva, NJ Machado, ... Journal of Neuroscience 29 (47), 14741-14751, 2009 | 394 | 2009 |
| Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress MP Kaster, NJ Machado, HB Silva, A Nunes, AP Ardais, M Santana, ... Proceedings of the National Academy of Sciences 112 (25), 7833-7838, 2015 | 304 | 2015 |
| Adenosine receptor antagonists including caffeine alter fetal brain development in mice CG Silva, C Métin, W Fazeli, NJ Machado, S Darmopil, PS Launay, ... Science translational medicine 5 (197), 197ra104-197ra104, 2013 | 183 | 2013 |
| Astrocytic adenosine A 2A receptors control the amyloid-β peptide-induced decrease of glutamate uptake M Matos, E Augusto, NJ Machado, A dos Santos-Rodrigues, RA Cunha, ... Journal of Alzheimer's Disease 31 (3), 555-567, 2012 | 146 | 2012 |
| Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease D Rial, AA Castro, N Machado, P Garção, FQ Gonçalves, HB Silva, ... PloS one 9 (12), e114216, 2014 | 123 | 2014 |
| Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder P Pandolfo, NJ Machado, A Köfalvi, RN Takahashi, RA Cunha European Neuropsychopharmacology 23 (4), 317-328, 2013 | 119 | 2013 |
| Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies C Carvalho, N Machado, PC Mota, SC Correia, S Cardoso, RX Santos, ... Journal of Alzheimer's Disease 35 (3), 623-635, 2013 | 94 | 2013 |
| Adenosine A2A receptors in the amygdala control synaptic plasticity and contextual fear memory AP Simões, NJ Machado, N Gonçalves, MP Kaster, AT Simões, A Nunes, ... Neuropsychopharmacology 41 (12), 2862-2871, 2016 | 86 | 2016 |
| Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease AC Silva, C Lemos, FQ Gonçalves, AV Pliássova, NJ Machado, HB Silva, ... Neurobiology of disease 117, 72-81, 2018 | 78 | 2018 |
| Liraglutide Protects Against Brain Amyloid-β1–42 Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative … AI Duarte, E Candeias, IN Alves, D Mena, DF Silva, NJ Machado, ... International journal of molecular sciences 21 (5), 1746, 2020 | 60 | 2020 |
| The role of parkinson's disease‐associated receptor GPR 37 in the hippocampus: functional interplay with the adenosinergic system JP Lopes, X Morató, C Souza, C Pinhal, NJ Machado, PM Canas, ... Journal of Neurochemistry 134 (1), 135-146, 2015 | 58 | 2015 |
| Central ghrelin resistance permits the overconsolidation of fear memory ES Harmatz, L Stone, SH Lim, G Lee, A McGrath, B Gisabella, X Peng, ... Biological psychiatry 81 (12), 1003-1013, 2017 | 57 | 2017 |
| Neuronal adenosine A2A receptors are critical mediators of neurodegeneration triggered by convulsions PM Canas, LO Porciúncula, AP Simões, E Augusto, HB Silva, ... Eneuro 5 (6), 2018 | 56 | 2018 |
| Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate … NJ Machado, AP Simões, HB Silva, AP Ardais, MP Kaster, P Garção, ... Molecular neurobiology 54, 1552-1563, 2017 | 55 | 2017 |
| Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder DT Leffa, SG Ferreira, NJ Machado, CM Souza, F Rosa, C de Carvalho, ... European Journal of Neuroscience 49 (12), 1673-1683, 2019 | 31 | 2019 |
| Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making DT Leffa, P Pandolfo, N Gonçalves, NJ Machado, CM De Souza, JI Real, ... Frontiers in Molecular Neuroscience 11, 475, 2018 | 16 | 2018 |
| Imidazole alkaloids inhibit the pro-inflammatory mechanisms of human neutrophil and exhibit anti-inflammatory properties in vivo TM Rocha, NJ Machado, JAC de Sousa, EVO Araujo, MA Guimaraes, ... Journal of Pharmacy and Pharmacology 71 (5), 849-859, 2019 | 14 | 2019 |
| Medicinal plants containing coumarin or essential oils from the brazilian biome may be new option for treating leishmaniasis? ES Silveira, NLDC Rodrigues, NM de Jesus Machado, FRM Fonseca, ... Pharmacognosy Reviews 14 (27), 53, 2020 | 7 | 2020 |
