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Zhen Li | 李桢
Zhen Li | 李桢
Project Scientist, Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center
Dirección de correo verificada de cshs.org
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pH-controlled hydrogen sulfide release for myocardial ischemia-reperfusion injury
J Kang, Z Li, CL Organ, CM Park, C Yang, A Pacheco, D Wang, DJ Lefer, ...
Journal of the American Chemical Society 138 (20), 6336-6339, 2016
2342016
A Novel Hydrogen Sulfide Prodrug, SG 1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients
DJ Polhemus, Z Li, CB Pattillo, G Gojon Sr, G Gojon Jr, T Giordano, ...
Cardiovascular therapeutics 33 (4), 216-226, 2015
1552015
Evolution of Hydrogen Sulfide Therapeutics to Treat Cardiovascular Disease
Z Li, DJ Polhemus, DJ Lefer
Circulation Research 123 (5), 590-600, 2018
1112018
An Esterase‐Sensitive Prodrug Approach for Controllable Delivery of Persulfide Species
Y Zheng, B Yu, Z Li, Z Yuan, CL Organ, RK Trivedi, S Wang, DJ Lefer, ...
Angewandte Chemie 129 (39), 11911-11915, 2017
902017
Renal denervation prevents heart failure progression via inhibition of the renin-angiotensin system
TE Sharp III, DJ Polhemus, Z Li, P Spaletra, JS Jenkins, JP Reilly, ...
Journal of the American College of Cardiology 72 (21), 2609-2621, 2018
892018
Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors
Y Zhao, C Yang, C Organ, Z Li, S Bhushan, H Otsuka, A Pacheco, J Kang, ...
Journal of medicinal chemistry 58 (18), 7501-7511, 2015
842015
Renal sympathetic denervation protects the failing heart via inhibition of neprilysin activity in the kidney
DJ Polhemus, RK Trivedi, J Gao, Z Li, AL Scarborough, TT Goodchild, ...
Journal of the American College of Cardiology 70 (17), 2139-2153, 2017
812017
Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure
CL Organ, Z Li, TE Sharp III, DJ Polhemus, N Gupta, TT Goodchild, ...
Journal of the American Heart Association 9 (10), e016223, 2020
732020
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase
M Peleli, SI Bibli, Z Li, A Chatzianastasiou, A Varela, A Katsouda, ...
Biochemical pharmacology 176, 113833, 2020
522020
Combined Angiotensin Receptor–Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure
RK Trivedi, DJ Polhemus, Z Li, D Yoo, H Koiwaya, A Scarborough, ...
Journal of the American Heart Association 7 (5), e008268, 2018
522018
Hydrogen sulfide ameliorates homocysteine-induced cardiac remodeling and dysfunction
S Kar, HR Shahshahan, TN Kambis, SK Yadav, Z Li, DJ Lefer, PK Mishra
Frontiers in physiology 10, 598, 2019
392019
Hydrogen sulfide attenuates renin angiotensin and aldosterone pathological signaling to preserve kidney function and improve exercise tolerance in heart failure
Z Li, CL Organ, J Kang, DJ Polhemus, RK Trivedi, TE Sharp, JS Jenkins, ...
JACC: Basic to Translational Science 3 (6), 796-809, 2018
362018
Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure
Z Li, H Xia, TE Sharp III, KB LaPenna, JW Elrod, KM Casin, K Liu, ...
Circulation Research 131 (3), 222-235, 2022
332022
Effects of a novel hydrogen sulfide prodrug in a porcine model of acute limb ischemia
AM Rushing, E Donnarumma, DJ Polhemus, KR Au, SE Victoria, ...
Journal of vascular surgery 69 (6), 1924-1935, 2019
322019
Novel Göttingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities
TE Sharp III, AL Scarborough, Z Li, DJ Polhemus, HA Hidalgo, ...
Basic to Translational Science 6 (2), 154-170, 2021
312021
Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP
KN Papanicolaou, D Ashok, T Liu, TM Bauer, J Sun, Z Li, E da Costa, ...
Journal of molecular and cellular cardiology 139, 176-189, 2020
312020
Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury
H Xia, Z Li, TE Sharp III, DJ Polhemus, J Carnal, KH Moles, YX Tao, ...
Journal of the American Heart Association 9 (19), e017544, 2020
292020
Hydrogen Sulfide as a Potential Therapy for Heart Failure—Past, Present, and Future
KB LaPenna, DJ Polhemus, JE Doiron, HA Hidalgo, Z Li, DJ Lefer
Antioxidants 10 (3), 485, 2021
232021
A novel mtDNA repair fusion protein attenuates maladaptive remodeling and preserves cardiac function in heart failure
JM Bradley, Z Li, CL Organ, DJ Polhemus, H Otsuka, KN Islam, ...
American Journal of Physiology-Heart and Circulatory Physiology 314 (2 …, 2017
202017
A novel fibroblast activation inhibitor attenuates left ventricular remodeling and preserves cardiac function in heart failure
JM Bradley, P Spaletra, Z Li, TE Sharp 3rd, TT Goodchild, LG Corral, ...
American Journal of Physiology-Heart and Circulatory Physiology 315 (3 …, 2018
182018
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