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Sina Gharib
Sina Gharib
Professor of Medicine, University of Washington
Dirección de correo verificada de uw.edu
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Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
18782013
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
T Vaisar, S Pennathur, PS Green, SA Gharib, AN Hoofnagle, MC Cheung, ...
The Journal of clinical investigation 117 (3), 746-756, 2007
11152007
Epigenetic signatures of cigarette smoking
R Joehanes, AC Just, RE Marioni, LC Pilling, LM Reynolds, ...
Circulation: cardiovascular genetics 9 (5), 436-447, 2016
7862016
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
DB Hancock, M Eijgelsheim, JB Wilk, SA Gharib, LR Loehr, KD Marciante, ...
Nature genetics 42 (1), 45-52, 2010
7192010
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
7042021
The transcriptional landscape of age in human peripheral blood
MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ...
Nature communications 6 (1), 1-14, 2015
5912015
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ...
Nature genetics 51 (2), 245-257, 2019
5762019
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
4882018
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
F Demenais, P Margaritte-Jeannin, KC Barnes, WOC Cookson, ...
Nature genetics 50 (1), 42-53, 2018
4762018
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
MS Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, ...
Nature genetics 43 (11), 1082-1090, 2011
4752011
Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis
C Hung, G Linn, YH Chow, A Kobayashi, K Mittelsteadt, WA Altemeier, ...
American journal of respiratory and critical care medicine 188 (7), 820-830, 2013
3912013
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
N Sotoodehnia, A Isaacs, PIW De Bakker, M Dörr, C Newton-Cheh, ...
Nature genetics 42 (12), 1068-1076, 2010
3832010
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
BD Hobbs, K De Jong, M Lamontagne, Y Bossé, N Shrine, MS Artigas, ...
Nature genetics 49 (3), 426-432, 2017
3682017
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
P Sakornsakolpat, D Prokopenko, M Lamontagne, NF Reeve, AL Guyatt, ...
Nature genetics 51 (3), 494-505, 2019
2942019
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis
G Campanholle, G Ligresti, SA Gharib, JS Duffield
American Journal of Physiology-Cell Physiology 304 (7), C591-C603, 2013
2312013
Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction
JB Wilk, NRG Shrine, LR Loehr, JH Zhao, A Manichaikul, LM Lopez, ...
American journal of respiratory and critical care medicine 186 (7), 622-632, 2012
2292012
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
C Schrimpf, C Xin, G Campanholle, SE Gill, W Stallcup, SL Lin, GE Davis, ...
Journal of the American Society of Nephrology 23 (5), 868-883, 2012
2252012
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik
Nature communications 10 (1), 3300, 2019
2122019
Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study.
RT Lee, SG Richardson, HM Loree, AJ Grodzinsky, SA Gharib, FJ Schoen, ...
Arteriosclerosis and thrombosis: a journal of vascular biology 12 (1), 1-5, 1992
2021992
Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation
WA Altemeier, G Matute-Bello, SA Gharib, RW Glenny, TR Martin, ...
The Journal of Immunology 175 (5), 3369-3376, 2005
1952005
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Artículos 1–20