piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans A Ashe, A Sapetschnig, EM Weick, J Mitchell, MP Bagijn, AC Cording, ... Cell 150 (1), 88-99, 2012 | 822 | 2012 |
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline PP Das, MP Bagijn, LD Goldstein, JR Woolford, NJ Lehrbach, ... Molecular cell 31 (1), 79-90, 2008 | 494 | 2008 |
Function, targets, and evolution of Caenorhabditis elegans piRNAs MP Bagijn, LD Goldstein, A Sapetschnig, EM Weick, S Bouasker, ... Science 337 (6094), 574-578, 2012 | 403 | 2012 |
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans NJ Lehrbach, J Armisen, HL Lightfoot, KJ Murfitt, A Bugaut, ... Nature structural & molecular biology 16 (10), 1016-1020, 2009 | 300 | 2009 |
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1 NJ Lehrbach, G Ruvkun elife 5, e17721, 2016 | 234 | 2016 |
A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity A Ashe, T Bélicard, J Le Pen, P Sarkies, L Frézal, NJ Lehrbach, MA Félix, ... elife 2, e00994, 2013 | 181 | 2013 |
Tertiary siRNAs Mediate Paramutation in C. elegans A Sapetschnig, P Sarkies, NJ Lehrbach, EA Miska PLoS Genetics 11 (3), e1005078, 2015 | 123 | 2015 |
Protein sequence editing of SKN-1A/Nrf1 by peptide: N-glycanase controls proteasome gene expression NJ Lehrbach, PC Breen, G Ruvkun Cell 177 (3), 737-750. e15, 2019 | 116 | 2019 |
Complex patterns of transcription at the insertion site of a retrotransposon in the mouse R Druker, TJ Bruxner, NJ Lehrbach, E Whitelaw Nucleic acids research 32 (19), 5800-5808, 2004 | 115 | 2004 |
A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans M Jovanovic, L Reiter, P Picotti, V Lange, E Bogan, B A Hurschler, ... Nature methods 7 (10), 837-842, 2010 | 97 | 2010 |
The Conserved miR-51 microRNA Family Is Redundantly Required for Embryonic Development and Pharynx Attachment in Caenorhabditis elegans WR Shaw, J Armisen, NJ Lehrbach, EA Miska Genetics 185 (3), 897-905, 2010 | 80 | 2010 |
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity NJ Lehrbach, G Ruvkun Elife 8, e44425, 2019 | 72 | 2019 |
Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans NJ Lehrbach, C Castro, KJ Murfitt, C Abreu-Goodger, JL Griffin, EA Miska Rna 18 (12), 2220-2235, 2012 | 67 | 2012 |
A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing HL Lightfoot, A Bugaut, J Armisen, NJ Lehrbach, EA Miska, ... Biochemistry 50 (35), 7514-7521, 2011 | 54 | 2011 |
A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks C Castro, J Krumsiek, NJ Lehrbach, SA Murfitt, EA Miska, JL Griffin Molecular BioSystems 9 (7), 1632-1642, 2013 | 50 | 2013 |
RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans A Akay, A Craig, N Lehrbach, M Larance, E Pourkarimi, JE Wright, ... Open biology 3 (11), 130151, 2013 | 30 | 2013 |
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility AG Charlesworth, U Seroussi, NJ Lehrbach, MS Renaud, AE Sundby, ... Nucleic Acids Research 49 (15), 8836-8865, 2021 | 29 | 2021 |
Regulation and functions of the ER-associated Nrf1 transcription factor G Ruvkun, N Lehrbach Cold Spring Harbor Perspectives in Biology 15 (1), a041266, 2023 | 27 | 2023 |
Next‐Generation Sequencing for Identification of EMS‐Induced Mutations in Caenorhabditis elegans NJ Lehrbach, F Ji, R Sadreyev Current protocols in molecular biology 117 (1), 7.29. 1-7.29. 12, 2017 | 27 | 2017 |
Regulation of pre-miRNA Processing NJ Lehrbach, EA Miska Adv Exp Med Biol 700 (4), 67-75, 2010 | 24 | 2010 |