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Fabian Grimm
Fabian Grimm
Clariant
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Metabolism and metabolites of polychlorinated biphenyls
FA Grimm, D Hu, I Kania-Korwel, HJ Lehmler, G Ludewig, KC Hornbuckle, ...
Critical reviews in toxicology 45 (3), 245-272, 2015
4202015
High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes
FA Grimm, Y Iwata, O Sirenko, M Bittner, I Rusyn
Assay and drug development technologies 13 (9), 529-546, 2015
1242015
Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin
FA Grimm, HJ Lehmler, X He, LW Robertson, MW Duffel
Environmental health perspectives 121 (6), 657-662, 2013
1082013
ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models
SW Marvel, K To, FA Grimm, FA Wright, I Rusyn, DM Reif
BMC bioinformatics 19, 1-7, 2018
1032018
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
FA Grimm, Y Iwata, O Sirenko, GA Chappell, FA Wright, DM Reif, ...
Green chemistry 18 (16), 4407-4419, 2016
862016
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model
O Sirenko, FA Grimm, KR Ryan, Y Iwata, WA Chiu, F Parham, JA Wignall, ...
Toxicology and applied pharmacology 322, 60-74, 2017
812017
Technology transfer of the microphysiological systems: a case study of the human proximal tubule tissue chip
C Sakolish, EJ Weber, EJ Kelly, J Himmelfarb, R Mouneimne, FA Grimm, ...
Scientific reports 8 (1), 14882, 2018
782018
A pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics
JS House, FA Grimm, DD Jima, YH Zhou, I Rusyn, FA Wright
Frontiers in genetics 8, 304319, 2017
562017
Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes
SD Burnett, AD Blanchette, FA Grimm, JS House, DM Reif, FA Wright, ...
Toxicology and applied pharmacology 381, 114711, 2019
552019
Tissue distribution, metabolism, and excretion of 3, 3′-dichloro-4′-sulfooxy-biphenyl in the rat
FA Grimm, X He, LM Teesch, HJ Lehmler, LW Robertson, MW Duffel
Environmental science & technology 49 (13), 8087-8095, 2015
482015
A human population-based organotypic in vitro model for cardiotoxicity screening
FA Grimm, A Blanchette, JS House, K Ferguson, NH Hsieh, C Dalaijamts, ...
Altex 35 (4), 441, 2018
472018
Identification of a sulfate metabolite of PCB 11 in human serum
FA Grimm, HJ Lehmler, WX Koh, J DeWall, LM Teesch, KC Hornbuckle, ...
Environment international 98, 120-128, 2017
432017
Revealing adverse outcome pathways from public high-throughput screening data to evaluate new toxicants by a knowledge-based deep neural network approach
HL Ciallella, DP Russo, LM Aleksunes, FA Grimm, H Zhu
Environmental science & technology 55 (15), 10875-10887, 2021
332021
Predictive modeling of estrogen receptor agonism, antagonism, and binding activities using machine-and deep-learning approaches
HL Ciallella, DP Russo, LM Aleksunes, FA Grimm, H Zhu
Laboratory investigation 101 (4), 490-502, 2021
322021
High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells
Y Iwata, WD Klaren, CS Lebakken, FA Grimm, I Rusyn
Assay and drug development technologies 15 (6), 267-279, 2017
322017
Cardiovascular effects of polychlorinated biphenyls and their major metabolites
FA Grimm, WD Klaren, X Li, HJ Lehmler, M Karmakar, LW Robertson, ...
Environmental health perspectives 128 (7), 077008, 2020
312020
Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration‐QTc Relationships
AD Blanchette, FA Grimm, C Dalaijamts, NH Hsieh, K Ferguson, YS Luo, ...
Clinical Pharmacology & Therapeutics 105 (5), 1175-1186, 2019
312019
Grouping of UVCB substances with new approach methodologies (NAMs) data
JS House, FA Grimm, WD Klaren, A Dalzell, S Kuchi, SD Zhang, K Lenz, ...
Altex 38 (1), 123, 2021
272021
A Bayesian Method for Population-wide Cardiotoxicity Hazard and Risk Characterization Using an In Vitro Human Model
AD Blanchette, SD Burnett, FA Grimm, I Rusyn, WA Chiu
Toxicological sciences 178 (2), 391-403, 2020
252020
Grouping of petroleum substances as example UVCBs by ion mobility-mass spectrometry to enable chemical composition-based read-across
FA Grimm, WK Russell, YS Luo, Y Iwata, WA Chiu, T Roy, PJ Boogaard, ...
Environmental science & technology 51 (12), 7197-7207, 2017
242017
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