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Christian Tackenberg
Christian Tackenberg
University of Zurich, Institute for Regenerative Medicine
Dirección de correo verificada de irem.uzh.ch - Página principal
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Divergent pathways mediate spine alterations and cell death induced by amyloid-β, wild-type tau, and R406W tau
C Tackenberg, R Brandt
Journal of Neuroscience 29 (46), 14439-14450, 2009
1722009
Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients
JH Birnbaum, D Wanner, AF Gietl, A Saake, TM Kündig, C Hock, ...
Stem cell research 27, 121-130, 2018
1502018
NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss
C Tackenberg, S Grinschgl, A Trutzel, AC Santuccione, MC Frey, ...
Cell death & disease 4 (4), e608-e608, 2013
1502013
Thin, stubby or mushroom: spine pathology in Alzheimer's disease
C Tackenberg, A Ghori, R Brandt
Current Alzheimer Research 6 (3), 261-268, 2009
1242009
Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau …
N Shahani, S Subramaniam, T Wolf, C Tackenberg, R Brandt
Journal of Neuroscience 26 (22), 6103-6114, 2006
1052006
Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss
JH Birnbaum, J Bali, L Rajendran, RM Nitsch, C Tackenberg
Cell death & disease 6 (6), e1791-e1791, 2015
1022015
APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes
SM de Leeuw, AWT Kirschner, K Lindner, R Rust, V Budny, WE Wolski, ...
Stem cell reports, 2022
702022
The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation
C Tackenberg, RM Nitsch
Molecular brain 12, 1-4, 2019
582019
Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation
L Kulic, J McAfoose, T Welt, C Tackenberg, C Späni, F Wirth, V Finder, ...
Translational psychiatry 2 (11), e183-e183, 2012
542012
Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D
L Penazzi, C Tackenberg, A Ghori, N Golovyashkina, B Niewidok, K Selle, ...
Neuropharmacology, 10.1016/j.neuropharm.2016.01.002, 2016
512016
Isoform-and cell-state-specific lipidation of ApoE in astrocytes
K Lindner, K Beckenbauer, LC van Ek, K Titeca, SM de Leeuw, K Awwad, ...
Cell reports 38 (9), 2022
492022
Deep learning-based behavioral profiling of rodent stroke recovery
RZ Weber, G Mulders, J Kaiser, C Tackenberg, R Rust
BMC biology 20 (1), 232, 2022
452022
Alzheimer’s in a dish – induced pluripotent stem cell-based disease modeling
SM de Leeuw, C Tackenberg
Translational Neurodegeneration, 2019
422019
A practical guide to the automated analysis of vascular growth, maturation and injury in the brain
R Rust, T Kirabali, L Grönnert, B Dogancay, YDP Limasale, A Meinhardt, ...
Frontiers in neuroscience 14, 244, 2020
402020
Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease
R Derungs, GG Camici, RD Spescha, T Welt, C Tackenberg, C Späni, ...
Molecular psychiatry 22 (4), 605-614, 2017
362017
Characterization of the blood brain barrier disruption in the photothrombotic stroke model
RZ Weber, L Grönnert, G Mulders, MA Maurer, C Tackenberg, ...
Frontiers in physiology 11, 586226, 2020
352020
Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice
AC Santuccione, M Merlini, A Shetty, C Tackenberg, J Bali, MT Ferretti, ...
Molecular psychiatry 18 (3), 358-368, 2013
342013
Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an …
C Tackenberg, L Kulic, RM Nitsch
PloS one 15 (9), e0239584, 2020
312020
Increased maturation of iPSC-derived neurons in a hydrogel-based 3D culture
SM de Leeuw, S Davaz, D Wanner, V Milleret, M Ehrbar, A Gietl, ...
Journal of Neuroscience Methods 360, 109254, 2021
222021
Editing a gateway for cell therapy across the blood–brain barrier
B Achón Buil, C Tackenberg, R Rust
Brain 146 (3), 823-841, 2023
202023
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20