| Discovery of a Ni2+-dependent guanidine hydrolase in bacteria D Funck, M Sinn, JR Fleming, M Stanoppi, J Dietrich, R López-Igual, ... Nature 603 (7901), 515-521, 2022 | 33 | 2022 |
| Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere J Bogomolovas, JR Fleming, B Franke, B Manso, B Simon, A Gasch, ... EMBO reports 22 (10), e48018, 2021 | 32 | 2021 |
| Proteomic Identification of Immunodiagnostic Antigens for Trypanosoma vivax Infections in Cattle and Generation of a Proof-of-Concept Lateral Flow Test … JR Fleming, L Sastry, SJ Wall, L Sullivan, MAJ Ferguson PLoS neglected tropical diseases 10 (9), e0004977, 2016 | 30 | 2016 |
| CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex T Zhou, JR Fleming, B Franke, J Bogomolovas, I Barsukov, DJ Rigden, ... FEBS letters 590 (18), 3098-3110, 2016 | 30 | 2016 |
| Molecular characterisation of titin N2A and its binding of CARP reveals a titin/actin cross-linking mechanism T Zhou, JR Fleming, S Lange, AL Hessel, J Bogomolovas, C Stronczek, ... Journal of molecular biology 433 (9), 166901, 2021 | 26 | 2021 |
| Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human African trypanosomiasis L Sullivan, J Fleming, L Sastry, A Mehlert, SJ Wall, MAJ Ferguson PLoS neglected tropical diseases 8 (7), e2976, 2014 | 26 | 2014 |
| Proteomic Selection of Immunodiagnostic Antigens for Trypanosoma congolense JR Fleming, L Sastry, TWM Crozier, GB Napier, L Sullivan, MAJ Ferguson PLoS neglected tropical diseases 8 (6), e2936, 2014 | 23 | 2014 |
| Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I J Bogomolovas, JR Fleming, BR Anderson, R Williams, S Lange, B Simon, ... Open biology 6 (9), 160114, 2016 | 22 | 2016 |
| The N2A region of titin has a unique structural configuration C Stronczek, S Lange, B Bullard, S Wolniak, E Börgeson, O Mayans, ... Journal of General Physiology 153 (7), e202012766, 2021 | 16 | 2021 |
| Exploring obscurin and SPEG kinase biology JR Fleming, A Rani, J Kraft, S Zenker, E Börgeson, S Lange Journal of Clinical Medicine 10 (5), 984, 2021 | 14 | 2021 |
| Scalable, Non-denaturing Purification of Phosphoproteins Using Ga3+-IMAC: N2A and M1M2 Titin Components as Study case M Adams, JR Fleming, E Riehle, T Zhou, T Zacharchenko, M Markovic, ... The protein journal 38, 181-189, 2019 | 13 | 2019 |
| Self‐Assembling Proteins as High‐Performance Substrates for Embryonic Stem Cell Self‐Renewal CJ Hill, JR Fleming, M Mousavinejad, R Nicholson, SB Tzokov, ... Advanced Materials 31 (17), 1807521, 2019 | 10 | 2019 |
| Crystal structure of Leishmania major ADP-ribosylation factor-like 1 and a classification of related GTPase family members in this Kinetoplastid JR Fleming, A Dawson, WN Hunter Molecular and biochemical parasitology 174 (2), 141-144, 2010 | 9 | 2010 |
| Evolutionary morphing of tryptophan synthase: functional mechanisms for the enzymatic channeling of indole JR Fleming, M Schupfner, F Busch, A Baslé, A Ehrmann, R Sterner, ... Journal of molecular biology 430 (24), 5066-5079, 2018 | 8 | 2018 |
| The architecture of Trypanosoma brucei tubulin‐binding cofactor B and implications for function JR Fleming, RE Morgan, PK Fyfe, SM Kelly, WN Hunter The FEBS Journal 280 (14), 3270-3280, 2013 | 8 | 2013 |
| Pairwise sequence similarity mapping with PaSiMap: Reclassification of immunoglobulin domains from titin as case study K Su, O Mayans, K Diederichs, JR Fleming Computational and Structural Biotechnology Journal 20, 5409-5419, 2022 | 6 | 2022 |
| The importance of chain context in assessing small nucleotide variants in titin: in silico case study of the I10-I11 tandem and its arrhythmic right ventricular … JR Fleming, DJ Rigden, O Mayans Journal of Biomolecular Structure and Dynamics 39 (10), 3480-3490, 2021 | 6 | 2021 |
| The ZT biopolymer: A self-assembling protein scaffold for stem cell applications Y Nesterenko, CJ Hill, JR Fleming, P Murray, O Mayans International Journal of Molecular Sciences 20 (17), 4299, 2019 | 6 | 2019 |
| Guanidino acid hydrolysis by the human enzyme annotated as agmatinase M Sinn, M Stanoppi, F Hauth, JR Fleming, D Funck, O Mayans, JS Hartig Scientific Reports 12 (1), 22088, 2022 | 5 | 2022 |
| Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death R Lambrecht, ME Delgado, V Gloe, K Schuetz, AP Plazzo, B Franke, ... Cell Reports 42 (12), 2023 | 4 | 2023 |
