Xin Lai
Xin Lai
Faculty of Medicine and Health Technology, Tampere University, Finland
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Understanding microRNA-mediated gene regulatory networks through mathematical modelling
X Lai, O Wolkenhauer, J Vera
Nucleic Acids Research 44 (13), 6019-6035, 2016
Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer
X Lai, M Eberhardt, U Schmitz, J Vera
Nucleic acids research 47 (15), 7753-7766, 2019
Artificial intelligence in cancer target identification and drug discovery
Y You, X Lai, Y Pan, H Zheng, J Vera, S Liu, S Deng, L Zhang
Signal Transduction and Targeted Therapy 7 (156), 2022
Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs
X Lai, U Schmitz, SK Gupta, A Bhattacharya, M Kunz, O Wolkenhauer, ...
Nucleic Acids Research 40 (18), 8818-8834, 2012
Cooperative gene regulation by microRNA pairs and their identification using a computational workflow
U Schmitz, X Lai, F Winter, O Wolkenhauer, J Vera, SK Gupta
Nucleic acids research 42 (12), 7539-7552, 2014
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance
X Lai, SK Gupta, U Schmitz, S Marquardt, S Knoll, A Spitschak, ...
Theranostics 8 (4), 1106-1120, 2018
Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network
J Vera, U Schmitz, X Lai, D Engelmann, FM Khan, O Wolkenhauer, ...
Cancer Research, 2013
MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology.
J Vera, X Lai, U Schmitz, O Wolkenhauer
Advances in experimental medicine and biology 774, 55-76, 2012
Exosomal lncRNAs and cancer: connecting the missing links
H Naderi-Meshkin, X Lai, R Amirkhah, J Vera, JEJ Rasko, U Schmitz
Bioinformatics 35 (2), 352-360, 2019
Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients
V Lieb, K Weigelt, L Scheinost, K Fischer, T Greither, M Marcou, G Theil, ...
Oncotarget, 2017
A gene regulatory architecture that controls region‐independent dynamics of oligodendrocyte differentiation
M Cantone, M Küspert, S Reiprich, X Lai, M Eberhardt, P Göttle, F Beyer, ...
Glia, 2019
Asthma phenotyping, therapy, and prevention: what can we learn from systems biology?
A Sittka, J Vera, X Lai, BT Schmeck
Pediatric research, 2013
A systems’ biology approach to study microRNA-mediated gene regulatory networks
X Lai, A Bhattacharya, U Schmitz, M Kunz, J Vera, O Wolkenhauer
BioMed Research International 2013, 2013
Modeling miRNA regulation in cancer signaling systems: miR-34a regulation of the p53/Sirt1 signaling module
X Lai, O Wolkenhauer, J Vera
Computational Modeling of Signaling Networks, 87-108, 2012
MicroRNA Clusters
X Lai, J Vera
Encyclopedia of Systems Biology, 1310-1314, 2013
Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a
JH Lee, J Dindorf, M Eberhardt, X Lai, C Ostalecki, N Koliha, S Gross, ...
Life science alliance 2 (2), 2019
Multiplicity of mathematical modeling strategies to search for molecular and cellular insights into bacteria lung infection
M Cantone, G Santos, P Wentker, X Lai, J Vera
Frontiers in physiology 8, 264848, 2017
A disease network‐based deep learning approach for characterizing melanoma
X Lai, J Zhou, A Wessely, M Heppt, A Maier, C Berking, J Vera, L Zhang
International Journal of Cancer, 2021
RNA sequencing of collecting duct renal cell carcinoma suggests an interaction between miRNA and target genes and a predominance of deregulated solute carrier genes
S Wach, H Taubert, K Weigelt, N Hase, M Köhn, D Misiak, S Hüttelmaier, ...
Cancers 12 (1), 64, 2020
THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila–a systems biology study
C Schulz, X Lai, W Bertrams, AL Jung, A Sittka-Stark, CE Herkt, H Janga, ...
Scientific reports 7 (1), 1-15, 2017
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