Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer K Halkidou, L Gaughan, S Cook, HY Leung, DE Neal, CN Robson The Prostate 59 (2), 177-189, 2004 | 722 | 2004 |
Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor L Gaughan, IR Logan, S Cook, DE Neal, CN Robson Journal of Biological Chemistry 277 (29), 25904-25913, 2002 | 390 | 2002 |
Tip60 is a nuclear hormone receptor coactivator ME Brady, DM Ozanne, L Gaughan, I Waite, S Cook, DE Neal, ... Journal of Biological Chemistry 274 (25), 17599-17604, 1999 | 314 | 1999 |
The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer EL Clark, A Coulson, C Dalgliesh, P Rajan, SM Nicol, S Fleming, R Heer, ... Cancer research 68 (19), 7938-7946, 2008 | 230 | 2008 |
Androgen receptor nuclear translocation is facilitated by the f-actin cross-linking protein filamin DM Ozanne, ME Brady, S Cook, L Gaughan, DE Neal, CN Robson Molecular endocrinology 14 (10), 1618-1626, 2000 | 230 | 2000 |
Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation L Gaughan, IR Logan, DE Neal, CN Robson Nucleic acids research 33 (1), 13-26, 2005 | 210 | 2005 |
Regulation of the androgen receptor by SET9-mediated methylation L Gaughan, J Stockley, N Wang, SRC McCracken, A Treumann, ... Nucleic acids research 39 (4), 1266-1279, 2011 | 147 | 2011 |
2, 4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer A Blomme, CA Ford, E Mui, R Patel, C Ntala, LE Jamieson, M Planque, ... Nature Communications 11 (1), 2508, 2020 | 141 | 2020 |
The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover K Coffey, L Rogerson, C Ryan-Munden, D Alkharaif, J Stockley, R Heer, ... Nucleic acids research 41 (8), 4433-4446, 2013 | 141 | 2013 |
Tip60 is a co-activator specific for class I nuclear hormone receptors L Gaughan, ME Brady, S Cook, DE Neal, CN Robson Journal of Biological Chemistry 276 (50), 46841-46848, 2001 | 122 | 2001 |
Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer IR Logan, L Gaughan, SRC McCracken, V Sapountzi, HY Leung, ... Molecular and cellular biology, 2006 | 113 | 2006 |
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity A Axon, FEB May, LE Gaughan, FM Williams, PG Blain, MC Wright Toxicology 298 (1-3), 40-51, 2012 | 99 | 2012 |
Deubiquitinating enzyme Usp12 is a novel co-activator of the androgen receptor UL Burska, VJ Harle, K Coffey, S Darby, H Ramsey, D O'Neill, IR Logan, ... Journal of Biological Chemistry 288 (45), 32641-32650, 2013 | 96 | 2013 |
Control of human PIRH2 protein stability: involvement of TIP60 and the proteasome IR Logan, V Sapountzi, L Gaughan, DE Neal, CN Robson Journal of Biological Chemistry 279 (12), 11696-11704, 2004 | 92 | 2004 |
The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer MA Wade, D Jones, L Wilson, J Stockley, K Coffey, CN Robson, ... Nucleic acids research 43 (1), 196-207, 2015 | 91 | 2015 |
AZD3514: A Small Molecule That Modulates Androgen Receptor Signaling and Function In Vitro and In Vivo SA Loddick, SJ Ross, AG Thomason, DM Robinson, GE Walker, ... Molecular cancer therapeutics 12 (9), 1715-1727, 2013 | 90 | 2013 |
A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions S Awasthi, A Sharma, K Wong, J Zhang, EF Matlock, L Rogers, P Motloch, ... Molecular and cellular biology, 2005 | 89 | 2005 |
The RNA‐binding and adaptor protein Sam68 modulates signal‐dependent splicing and transcriptional activity of the androgen receptor P Rajan, L Gaughan, C Dalgliesh, A El‐Sherif, CN Robson, HY Leung, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 88 | 2008 |
KDM4B is a master regulator of the estrogen receptor signalling cascade L Gaughan, J Stockley, K Coffey, D O’Neill, DL Jones, M Wade, J Wright, ... Nucleic acids research 41 (14), 6892-6904, 2013 | 87 | 2013 |
Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors IG Mills, L Gaughan, C Robson, T Ross, S McCracken, J Kelly, DE Neal The Journal of cell biology 170 (2), 191-200, 2005 | 86 | 2005 |