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William Grubbe
William Grubbe
Institute for Protein Design
Dirección de correo verificada de uw.edu
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In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design
AS Karim, QM Dudley, A Juminaga, Y Yuan, SA Crowe, JT Heggestad, ...
Nature Chemical Biology 16 (8), 912-919, 2020
2122020
Cell-free styrene biosynthesis at high titers
WS Grubbe, BJ Rasor, A Krüger, MC Jewett, AS Karim
Metabolic Engineering 61, 89-95, 2020
682020
Recent and future perspectives on engineering interferons and other cytokines as therapeutics
T Aung, WS Grubbe, RJ Nusbaum, JL Mendoza
Trends in biochemical sciences 48 (3), 259-273, 2023
172023
Distinct molecular phenotypes involving several human diseases are induced by IFN-λ3 and IFN-λ4 in monocyte-derived macrophages
M De, A Bhushan, WS Grubbe, S Roy, JL Mendoza, S Chinnaswamy
Genes & Immunity 23 (2), 73-84, 2022
42022
Molecular analysis of the type III interferon complex and its applications in protein engineering
WS Grubbe, F Byléhn, W Alvarado, JJ de Pablo, JL Mendoza
Biophysical Journal 122 (21), 4254-4263, 2023
22023
Structural studies of the IFNλ4 receptor complex using cryoEM enabled by protein engineering
WS Grubbe, B Zhang, A Kauffman, F Byléhn, K Padoł, HG Jung, SB Park, ...
Nature Communications 16 (1), 818, 2025
2025
Solution and Analysis of the IFNλ4 Receptor Complex Using CryoEM Enabled by Protein Engineering and Molecular Simulation
WS Grubbe
The University of Chicago, 2024
2024
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