Jason Shohet
Cited by
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Neuroblastoma: molecular pathogenesis and therapy
CU Louis, JM Shohet
Annual review of medicine 66, 49-63, 2015
The MYCN oncogene is a direct target of miR-34a
JS Wei, YK Song, S Durinck, QR Chen, ATC Cheuk, P Tsang, Q Zhang, ...
Oncogene 27 (39), 5204-5213, 2008
The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma
A Slack, Z Chen, R Tonelli, M Pule, L Hunt, A Pession, JM Shohet
Proceedings of the National Academy of Sciences 102 (3), 731-736, 2005
A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells
R Ghosh, LC Singh, JM Shohet, PH Gunaratne
Biomaterials 34 (3), 807-816, 2013
USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis
YH Fan, J Cheng, SA Vasudevan, J Dou, H Zhang, RH Patel, IT Ma, ...
Cell death & disease 4 (10), e867-e867, 2013
MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death
E Barbieri, P Mehta, Z Chen, L Zhang, A Slack, S Berg, JM Shohet
Molecular cancer therapeutics 5 (9), 2358-2365, 2006
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis
KA Honeycutt, Z Chen, MI Koster, M Miers, J Nuchtern, J Hicks, DR Roop, ...
Oncogene 25 (29), 4027-4032, 2006
Neuroblastoma pathogenesis: deregulation of embryonic neural crest development
JA Tomolonis, S Agarwal, JM Shohet
Cell and tissue research 372 (2), 245-262, 2018
Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis
R Tonelli, S Purgato, C Camerin, R Fronza, F Bologna, S Alboresi, ...
Molecular cancer therapeutics 4 (5), 779-786, 2005
WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma
Y Sun, JL Bell, D Carter, S Gherardi, RC Poulos, G Milazzo, JWH Wong, ...
Cancer research 75 (23), 5143-5154, 2015
Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma
JM Shohet, MJ Hicks, SE Plon, SM Burlingame, S Stuart, SY Chen, ...
Cancer research 62 (4), 1123-1128, 2002
G-CSF promotes neuroblastoma tumorigenicity and metastasis via STAT3-dependent cancer stem cell activation
S Agarwal, A Lakoma, Z Chen, J Hicks, LS Metelitsa, ES Kim, JM Shohet
Cancer research 75 (12), 2566-2579, 2015
A genome-wide search for promoters that respond to increased MYCN reveals both new oncogenic and tumor suppressor microRNAs associated with aggressive neuroblastoma
JM Shohet, R Ghosh, C Coarfa, A Ludwig, AL Benham, Z Chen, ...
Cancer research 71 (11), 3841-3851, 2011
The MDM2 small-molecule inhibitor RG7388 leads to potent tumor inhibition in p53 wild-type neuroblastoma
A Lakoma, E Barbieri, S Agarwal, J Jackson, Z Chen, Y Kim, M McVay, ...
Cell death discovery 1 (1), 1-9, 2015
The role of histone demethylase KDM4B in Myc signaling in neuroblastoma
J Yang, AM AlTahan, D Hu, Y Wang, PH Cheng, CL Morton, C Qu, ...
Journal of the National Cancer Institute 107 (6), djv080, 2015
G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic
DM Hsu, S Agarwal, A Benham, C Coarfa, DN Trahan, Z Chen, ...
Cancer research 73 (13), 4134-4146, 2013
Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma
DM Patterson, D Gao, DN Trahan, BA Johnson, A Ludwig, E Barbieri, ...
Angiogenesis 14, 255-266, 2011
Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
M Calao, EO Sekyere, HJ Cui, BB Cheung, WD Thomas, J Keating, ...
Oncogene 32 (31), 3616-3626, 2013
WIP1 phosphatase as a potential therapeutic target in neuroblastoma
M Richter, T Dayaram, AG Gilmartin, G Ganji, SK Pemmasani, ...
PloS one 10 (2), e0115635, 2015
Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma
E Barbieri, K De Preter, M Capasso, Z Chen, DM Hsu, GP Tonini, ...
Cancer research 74 (3), 765-774, 2014
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