| Neuroblastoma: molecular pathogenesis and therapy CU Louis, JM Shohet Annual review of medicine 66 (1), 49-63, 2015 | 437 | 2015 |
| The MYCN oncogene is a direct target of miR-34a JS Wei, YK Song, S Durinck, QR Chen, ATC Cheuk, P Tsang, Q Zhang, ... Oncogene 27 (39), 5204-5213, 2008 | 360 | 2008 |
| The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma A Slack, Z Chen, R Tonelli, M Pule, L Hunt, A Pession, JM Shohet Proceedings of the National Academy of Sciences 102 (3), 731-736, 2005 | 289 | 2005 |
| A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells R Ghosh, LC Singh, JM Shohet, PH Gunaratne Biomaterials 34 (3), 807-816, 2013 | 209 | 2013 |
| USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis YH Fan, J Cheng, SA Vasudevan, J Dou, H Zhang, RH Patel, IT Ma, ... Cell death & disease 4 (10), e867-e867, 2013 | 207 | 2013 |
| MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death E Barbieri, P Mehta, Z Chen, L Zhang, A Slack, S Berg, JM Shohet Molecular cancer therapeutics 5 (9), 2358-2365, 2006 | 167 | 2006 |
| Neuroblastoma pathogenesis: deregulation of embryonic neural crest development JA Tomolonis, S Agarwal, JM Shohet Cell and tissue research 372 (2), 245-262, 2018 | 137 | 2018 |
| Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis KA Honeycutt, Z Chen, MI Koster, M Miers, J Nuchtern, J Hicks, DR Roop, ... Oncogene 25 (29), 4027-4032, 2006 | 135 | 2006 |
| WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma Y Sun, JL Bell, D Carter, S Gherardi, RC Poulos, G Milazzo, JWH Wong, ... Cancer research 75 (23), 5143-5154, 2015 | 119 | 2015 |
| Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis R Tonelli, S Purgato, C Camerin, R Fronza, F Bologna, S Alboresi, ... Molecular cancer therapeutics 4 (5), 779-786, 2005 | 118 | 2005 |
| Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma JM Shohet, MJ Hicks, SE Plon, SM Burlingame, S Stuart, SY Chen, ... Cancer research 62 (4), 1123-1128, 2002 | 104 | 2002 |
| G-CSF promotes neuroblastoma tumorigenicity and metastasis via STAT3-dependent cancer stem cell activation S Agarwal, A Lakoma, Z Chen, J Hicks, LS Metelitsa, ES Kim, JM Shohet Cancer research 75 (12), 2566-2579, 2015 | 100 | 2015 |
| A genome-wide search for promoters that respond to increased MYCN reveals both new oncogenic and tumor suppressor microRNAs associated with aggressive neuroblastoma JM Shohet, R Ghosh, C Coarfa, A Ludwig, AL Benham, Z Chen, ... Cancer research 71 (11), 3841-3851, 2011 | 92 | 2011 |
| The MDM2 small-molecule inhibitor RG7388 leads to potent tumor inhibition in p53 wild-type neuroblastoma A Lakoma, E Barbieri, S Agarwal, J Jackson, Z Chen, Y Kim, M McVay, ... Cell death discovery 1 (1), 1-9, 2015 | 84 | 2015 |
| The role of histone demethylase KDM4B in Myc signaling in neuroblastoma J Yang, AM AlTahan, D Hu, Y Wang, PH Cheng, CL Morton, C Qu, ... Journal of the National Cancer Institute 107 (6), djv080, 2015 | 84 | 2015 |
| Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma DM Patterson, D Gao, DN Trahan, BA Johnson, A Ludwig, E Barbieri, ... Angiogenesis 14, 255-266, 2011 | 79 | 2011 |
| Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation M Calao, EO Sekyere, HJ Cui, BB Cheung, WD Thomas, J Keating, ... Oncogene 32 (31), 3616-3626, 2013 | 78 | 2013 |
| G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic DM Hsu, S Agarwal, A Benham, C Coarfa, DN Trahan, Z Chen, ... Cancer research 73 (13), 4134-4146, 2013 | 77 | 2013 |
| WIP1 phosphatase as a potential therapeutic target in neuroblastoma M Richter, T Dayaram, AG Gilmartin, G Ganji, SK Pemmasani, ... PloS one 10 (2), e0115635, 2015 | 74 | 2015 |
| Preclinical models of pediatric solid tumors (neuroblastoma) and their use in drug discovery DM Patterson, JM Shohet, ES Kim Current protocols in pharmacology 52 (1), 14.17. 1-14.17. 18, 2011 | 71 | 2011 |
Eugene S. KimCedars-Sinai Medical CenterVerified email at cshs.org
