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Barbara Weir
Barbara Weir
Principal Scientist, Janssen R&D
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA,IDH1,EGFR, and NF1
RGW Verhaak, KA Hoadley, E Purdom, V Wang, Y Qi, MD Wilkerson, ...
Cancer cell 17 (1), 98-110, 2010
78822010
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
R McLendon, A Friedman, D Bigner, EG Van Meir, DJ Brat, ...
Nature 455 (7216), 1061-1068, 2008
72812008
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
42312010
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ...
Nature 462 (7269), 108-112, 2009
31032009
Somatic mutations affect key pathways in lung adenocarcinoma
L Ding, G Getz, DA Wheeler, ER Mardis, MD McLellan, K Cibulskis, ...
Nature 455 (7216), 1069-1075, 2008
31002008
Next-generation characterization of the Cancer Cell Line Encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503, 2019
24342019
Defining a cancer dependency map
A Tsherniak, F Vazquez, PG Montgomery, BA Weir, G Kryukov, ...
Cell 170 (3), 564-576. e16, 2017
20522017
Absolute quantification of somatic DNA alterations in human cancer
SL Carter, K Cibulskis, E Helman, A McKenna, H Shen, T Zack, PW Laird, ...
Nature biotechnology 30 (5), 413, 2012
19932012
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ...
Nature genetics 49 (12), 1779, 2017
15512017
Characterizing the cancer genome in lung adenocarcinoma
BA Weir, MS Woo, G Getz, S Perner, L Ding, R Beroukhim, WM Lin, ...
Nature 450 (7171), 893-898, 2007
12752007
Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
K Shedden, JMG Taylor, SA Enkemann, MS Tsao, TJ Yeatman, ...
Nature medicine 14 (8), 822-827, 2008
11132008
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
AJ Bass, H Watanabe, CH Mermel, S Yu, S Perner, RG Verhaak, SY Kim, ...
Nature genetics 41 (11), 1238, 2009
10572009
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
J Rosenbluh, D Nijhawan, AG Cox, X Li, JT Neal, EJ Schafer, TI Zack, ...
Cell 151 (7), 1457-1473, 2012
8172012
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
J Barretina, BS Taylor, S Banerji, AH Ramos, M Lagos-Quintana, ...
Nature genetics 42 (8), 715, 2010
7882010
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR
ML Sos, M Koker, BA Weir, S Heynck, R Rabinovsky, T Zander, ...
Cancer research 69 (8), 3256-3261, 2009
6562009
Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting
AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ...
Cancer discovery 6 (8), 914-929, 2016
6462016
Highly parallel identification of essential genes in cancer cells
B Luo, HW Cheung, A Subramanian, T Sharifnia, M Okamoto, X Yang, ...
Proceedings of the National Academy of Sciences 105 (51), 20380-20385, 2008
6382008
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
CA Lovejoy, W Li, S Reisenweber, S Thongthip, J Bruno, T De Lange, ...
PLoS genetics 8 (7), e1002772, 2012
6182012
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
HW Cheung, GS Cowley, BA Weir, JS Boehm, S Rusin, JA Scott, A East, ...
Proceedings of the National Academy of Sciences 108 (30), 12372-12377, 2011
5022011
Prognostic and predictive gene signature for adjuvant chemotherapy in resected non–small-cell lung cancer
CQ Zhu, K Ding, D Strumpf, BA Weir, M Meyerson, N Pennell, RK Thomas, ...
Journal of Clinical Oncology 28 (29), 4417-4424, 2010
5002010
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