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Ashutosh Kumar, PhD, DABT
Ashutosh Kumar, PhD, DABT
Post doctoral fellow at NIH/NIEHS
Dirección de correo verificada de niehs.nih.gov
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Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis
S Chatterjee, D Ganini, EJ Tokar, A Kumar, S Das, J Corbett, MB Kadiiska, ...
Journal of hepatology 58 (4), 778-784, 2013
1452013
Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb-and paraquat-induced hepatotoxicity in rats
I Ahmad, S Shukla, A Kumar, BK Singh, V Kumar, AK Chauhan, D Singh, ...
Chemico-biological interactions 201 (1-3), 9-18, 2013
1132013
Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells
D Ganini, F Leinisch, A Kumar, JJ Jiang, EJ Tokar, CC Malone, ...
Redox biology 12, 462-468, 2017
1102017
Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells
A Kumar, SH Chen, MB Kadiiska, JS Hong, J Zielonka, B Kalyanaraman, ...
Free Radical Biology and Medicine 73, 51-59, 2014
912014
Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: similarity with paraquat neurotoxicity
A Kumar, BK Singh, I Ahmad, S Shukla, DK Patel, G Srivastava, V Kumar, ...
Brain Research 1438, 48-64, 2012
712012
Pesticides and metals induced Parkinson's disease: involvement of free radicals and oxidative stress.
C Singh, I Ahmad, A Kumar
Cellular and molecular biology (Noisy-le-Grand, France) 53 (5), 19, 2007
702007
The involvement of nitric oxide in maneb-and paraquat-induced oxidative stress in rat polymorphonuclear leukocytes
I Ahmad, A Kumar, S Shukla, H Prasad Pandey, C Singh
Free radical research 42 (10), 849-862, 2008
692008
Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis
S Das, RK Seth, A Kumar, MB Kadiiska, G Michelotti, AM Diehl, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 305 (12 …, 2013
682013
Environmental toxin–linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice
RK Seth, A Kumar, S Das, MB Kadiiska, G Michelotti, AM Diehl, ...
toxicological sciences 134 (2), 291-303, 2013
682013
Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats
A Kumar, I Ahmad, S Shukla, BK Singh, DK Patel, HP Pandey, C Singh
Free radical research 44 (8), 950-965, 2010
662010
Formation and implications of alpha-synuclein radical in maneb-and paraquat-induced models of Parkinson’s disease
A Kumar, F Leinisch, MB Kadiiska, J Corbett, RP Mason
Molecular neurobiology 53, 2983-2994, 2016
552016
Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson’s disease
A Kumar, D Ganini, RP Mason
Molecular Neurodegeneration 11, 1-12, 2016
532016
Proinflammatory Adipokine Leptin Mediates Disinfection Byproduct Bromodichloromethane-induced Early Steatohepatitic Injury in Obesity
S Das, A Kumar, RK Seth, EJ Tokar, MB Kadiiska, MP Waalkes, ...
Toxicology and Applied Pharmacology, 2013
452013
CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
RK Seth, S Das, A Kumar, A Chanda, MB Kadiiska, G Michelotti, ...
Toxicology and applied pharmacology 274 (1), 42-54, 2014
412014
Oxidative stress in zinc-induced dopaminergic neurodegeneration: Implications of superoxide dismutase and heme oxygenase-1
BK Singh, A Kumar, I Ahmad, V Kumar, DK Patel, SK Jain, C Singh
Free Radical Research 45 (10), 1207-1222, 2011
342011
Maneb and paraquat-induced modulation of toxicant responsive genes in the rat liver: comparison with polymorphonuclear leukocytes
I Ahmad, S Shukla, A Kumar, BK Singh, DK Patel, HP Pandey, C Singh
Chemico-biological interactions 188 (3), 566-579, 2010
332010
Chronic endurance exercise impairs cardiac structure and function in middle-aged mice with impaired Nrf2 signaling
G Shanmugam, M Narasimhan, RL Conley, T Sairam, A Kumar, ...
Frontiers in physiology 8, 268, 2017
312017
Nitric oxide inhibits topoisomerase II activity and induces resistance to topoisomerase II-poisons in human tumor cells
A Kumar, M Ehrenshaft, EJ Tokar, RP Mason, BK Sinha
Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (7), 1519-1527, 2016
272016
Nitric oxide down-regulates topoisomerase I and induces camptothecin resistance in human breast MCF-7 tumor cells
NK Sharma, A Kumar, A Kumari, EJ Tokar, MP Waalkes, CD Bortner, ...
PloS one 10 (11), e0141897, 2015
272015
Effect of nitric oxide on the anticancer activity of the topoisomerase-active drugs etoposide and adriamycin in human melanoma cells
BK Sinha, A Kumar, S Bhattacharjee, MG Espey, RP Mason
Journal of Pharmacology and Experimental Therapeutics 347 (3), 607-614, 2013
272013
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Artículos 1–20