Magdalini Polymenidou
Magdalini Polymenidou
Associate Professor for Biomedicine, Department of Quantitative Biomedicine, University of Zurich
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Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis
SC Ling, M Polymenidou, DW Cleveland
Neuron 79 (3), 416-438, 2013
Protein phase separation: a new phase in cell biology
S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ...
Trends in cell biology 28 (6), 420-435, 2018
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
M Polymenidou, C Lagier-Tourenne, KR Hutt, SC Huelga, J Moran, ...
Nature neuroscience 14 (4), 459-468, 2011
Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
H Ilieva, M Polymenidou, DW Cleveland
Journal of Cell Biology 187 (6), 761-772, 2009
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
C Lagier-Tourenne, M Polymenidou, DW Cleveland
Human molecular genetics 19 (R1), R46-R64, 2010
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ...
Nature neuroscience 15 (11), 1488-1497, 2012
Mammalian prion biology: one century of evolving concepts
A Aguzzi, M Polymenidou
Cell 116 (2), 313-327, 2004
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
C Lagier-Tourenne, M Baughn, F Rigo, S Sun, P Liu, HR Li, J Jiang, ...
Proceedings of the National Academy of Sciences 110 (47), E4530-E4539, 2013
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
M Heikenwalder, M Polymenidou, T Junt, C Sigurdson, H Wagner, S Akira, ...
Nature medicine 10 (2), 187-192, 2004
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
ES Arnold, SC Ling, SC Huelga, C Lagier-Tourenne, M Polymenidou, ...
Proceedings of the National Academy of Sciences 110 (8), E736-E745, 2013
The seeds of neurodegeneration: prion-like spreading in ALS
M Polymenidou, DW Cleveland
Cell 147 (3), 498-508, 2011
Insights into prion strains and neurotoxicity
A Aguzzi, M Heikenwalder, M Polymenidou
Nature reviews Molecular cell biology 8 (7), 552-561, 2007
Prion strain discrimination using luminescent conjugated polymers
CJ Sigurdson, KPR Nilsson, S Hornemann, G Manco, M Polymenidou, ...
Nature methods 4 (12), 1023-1030, 2007
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
T Afroz, EM Hock, P Ernst, C Foglieni, M Jambeau, LAB Gilhespy, ...
Nature communications 8 (1), 45, 2017
Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease
M Polymenidou, K Stoeck, M Glatzel, M Vey, A Bellon, A Aguzzi
The Lancet Neurology 4 (12), 805-814, 2005
Prion-like spread of protein aggregates in neurodegeneration
M Polymenidou, DW Cleveland
Journal of Experimental Medicine 209 (5), 889-893, 2012
Phase separation and neurodegenerative diseases: a disturbance in the force
A Zbinden, M Pérez-Berlanga, P De Rossi, M Polymenidou
Developmental cell 55 (1), 45-68, 2020
Misregulated RNA processing in amyotrophic lateral sclerosis
M Polymenidou, C Lagier-Tourenne, KR Hutt, CF Bennett, DW Cleveland, ...
Brain research 1462, 3-15, 2012
Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8
J Kranich, NJ Krautler, E Heinen, M Polymenidou, C Bridel, ...
The Journal of experimental medicine 205 (6), 1293-1302, 2008
The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes
M Polymenidou, R Moos, M Scott, C Sigurdson, Y Shi, B Yajima, ...
PloS one 3 (12), e3872, 2008
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