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Gustavo Benaim
Gustavo Benaim
Instituto de Biologia Experimental (IBE). Facultad de Ciencias. Universidad Central de Venezuela
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Amiodarone Has Intrinsic Anti-Trypanosoma cruzi Activity and Acts Synergistically with Posaconazole
G Benaim, JM Sanders, Y Garcia-Marchán, C Colina, R Lira, AR Caldera, ...
Journal of medicinal chemistry 49 (3), 892-899, 2006
2442006
Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region
ME Grillet, JV Hernández-Villena, MS Llewellyn, AE Paniz-Mondolfi, ...
The Lancet Infectious Diseases 19 (5), e149-e161, 2019
2082019
Phosphorylation of calmodulin: functional implications
G Benaim, A Villalobo
European Journal of Biochemistry 269 (15), 3619-3631, 2002
2032002
Different conformational states of the purified Ca2+-ATPase of the erythrocyte plasma membrane revealed by controlled trypsin proteolysis.
G Benaim, M Zurini, E Carafoli
Journal of Biological Chemistry 259 (13), 8471-8477, 1984
1211984
Amiodarone Destabilizes Intracellular Ca2+ Homeostasis and Biosynthesis of Sterols in Leishmania mexicana
X Serrano-Martín, Y García-Marchan, A Fernandez, N Rodriguez, H Rojas, ...
Antimicrobial Agents and Chemotherapy 53 (4), 1403-1410, 2009
992009
Mechanism of action of miltefosine on Leishmania donovani involves the impairment of acidocalcisome function and the activation of the sphingosine-dependent plasma membrane …
AK Pinto-Martinez, J Rodriguez-Durán, X Serrano-Martin, ...
Antimicrobial agents and chemotherapy 62 (1), 10.1128/aac. 01614-17, 2018
952018
Na+ entry via glutamate transporter activates the reverse Na+/Ca2+ exchange and triggers ‐induced Ca2+ release in rat cerebellar Type‐1 astrocytes
H Rojas, C Colina, M Ramos, G Benaim, EH Jaffe, C Caputo, R DiPolo
Journal of neurochemistry 100 (5), 1188-1202, 2007
952007
Targeting calcium homeostasis as the therapy of Chagas’ disease and leishmaniasis–a review
G Benaim, C Garcia
Tropical Biomedicine, 2011
872011
Amiodarone and Miltefosine Act Synergistically against Leishmania mexicana and Can Induce Parasitological Cure in a Murine Model of Cutaneous Leishmaniasis
X Serrano-Martín, G Payares, M De Lucca, JC Martinez, A Mendoza-León, ...
Antimicrobial Agents and Chemotherapy 53 (12), 5108-5113, 2009
872009
A calmodulin-activated (Ca2+-Mg2+)-ATPase is involved in Ca2+ transport by plasma membrane vesicles from Trypanosoma cruzi
G Benaim, S Losada, FR Gadelha, R Docampo
Biochemical Journal 280 (3), 715-720, 1991
861991
Ca2+ transport in isolated mitochondrial vesicles from Leishmania braziliensis promastigotes
G Benaim, R Bermudez, JA Urbina
Molecular and biochemical parasitology 39 (1), 61-68, 1990
831990
A calmodulin-stimulated Ca2+ pump in plasma-membrane vesicles from Trypanosoma brucei; selective inhibition by pentamidine
G Benaim, C Lopez-Estrano, R Docampo, SNJ Moreno
Biochemical Journal 296 (3), 759-763, 1993
771993
SQ109, a new drug lead for Chagas disease
P Veiga-Santos, K Li, L Lameira, TMU De Carvalho, G Huang, M Galizzi, ...
Antimicrobial agents and chemotherapy 59 (4), 1950-1961, 2015
732015
The emerging role of amiodarone and dronedarone in Chagas disease
G Benaim, AE Paniz Mondolfi
Nature Reviews Cardiology 9 (10), 605-609, 2012
732012
A calcium pump in plasma membrane vesicles from Leishmania braziliensis
G Benaim, PJ Romero
Biochimica et Biophysica Acta (BBA)-Biomembranes 1027 (1), 79-84, 1990
651990
In Vitro Anti-Trypanosoma cruzi Activity of Dronedarone, a Novel Amiodarone Derivative with an Improved Safety Profile
G Benaim, V Hernandez-Rodriguez, S Mujica-Gonzalez, L Plaza-Rojas, ...
Antimicrobial agents and chemotherapy 56 (7), 3720-3725, 2012
622012
The marine sponge toxin agelasine B increases the intracellular Ca2+ concentration and induces apoptosis in human breast cancer cells (MCF-7)
AA Pimentel, P Felibertt, F Sojo, L Colman, A Mayora, ML Silva, H Rojas, ...
Cancer chemotherapy and pharmacology 69, 71-83, 2012
602012
Successful Treatment of Old World Cutaneous Leishmaniasis Caused by Leishmania infantum with Posaconazole
AE Paniz Mondolfi, C Stavropoulos, T Gelanew, E Loucas, ...
Antimicrobial Agents and Chemotherapy 55 (4), 1774-1776, 2011
602011
Ceramide-1-P induces Ca2+ mobilization in Jurkat T-cells by elevation of Ins (1, 4, 5)-P3 and activation of a store-operated calcium channel
C Colina, A Flores, C Castillo, M del Rosario Garrido, A Israel, R DiPolo, ...
Biochemical and biophysical research communications 336 (1), 54-60, 2005
552005
Disruption of Intracellular Calcium Homeostasis as a Therapeutic Target Against Trypanosoma cruzi
G Benaim, AE Paniz-Mondolfi, EM Sordillo, N Martinez-Sotillo
Frontiers in cellular and infection microbiology 10, 46, 2020
532020
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