TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ... Neuron 95 (4), 808-816. e9, 2017 | 608 | 2017 |
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease SE Wahrle, H Jiang, M Parsadanian, J Kim, A Li, A Knoten, S Jain, ... The Journal of clinical investigation 118 (2), 671-682, 2008 | 452 | 2008 |
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain V Hirsch-Reinshagen, S Zhou, BL Burgess, L Bernier, SA McIsaac, ... Journal of Biological Chemistry 279 (39), 41197-41207, 2004 | 442 | 2004 |
24 (S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux K Abildayeva, PJ Jansen, V Hirsch-Reinshagen, VW Bloks, AHF Bakker, ... Journal of Biological Chemistry 281 (18), 12799-12808, 2006 | 294 | 2006 |
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease V Hirsch-Reinshagen, LF Maia, BL Burgess, JF Blain, KE Naus, ... Journal of Biological Chemistry 280 (52), 43243-43256, 2005 | 292 | 2005 |
ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor … JJ Donkin, S Stukas, V Hirsch-Reinshagen, D Namjoshi, A Wilkinson, ... Journal of Biological Chemistry 285 (44), 34144-34154, 2010 | 247 | 2010 |
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ... Journal of Neuroscience 29 (11), 3579-3589, 2009 | 159 | 2009 |
The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility DM Selva, V Hirsch-Reinshagen, B Burgess, S Zhou, J Chan, S McIsaac, ... Journal of Lipid Research 45 (6), 1040-1050, 2004 | 126 | 2004 |
Why lipids are important for Alzheimer disease? V Hirsch-Reinshagen, BL Burgess, CL Wellington Molecular and cellular biochemistry 326, 121-129, 2009 | 99 | 2009 |
LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins V Hirsch-Reinshagen, J Donkin, S Stukas, J Chan, A Wilkinson, J Fan, ... Journal of lipid research 50 (5), 885-893, 2009 | 79 | 2009 |
ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo BL Burgess, PF Parkinson, MM Racke, V Hirsch-Reinshagen, J Fan, ... Journal of lipid research 49 (6), 1254-1267, 2008 | 72 | 2008 |
Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease V Hirsch-Reinshagen, CL Wellington Current opinion in lipidology 18 (3), 325-332, 2007 | 72 | 2007 |
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of β-amyloid precursor protein GH Tansley, BL Burgess, MT Bryan, S Yuan, HR Veronica, P Jonathan, ... Journal of lipid research 48 (5), 1022-1034, 2007 | 69 | 2007 |
Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice B Burgess, K Naus, J Chan, V Hirsch-Reinshagen, G Tansley, L Matzke, ... Arteriosclerosis, thrombosis, and vascular biology 28 (10), 1731-1737, 2008 | 64 | 2008 |
Amyloid beta immunoreactivity in the retinal ganglion cell layer of the Alzheimer’s eye S Lee, K Jiang, B McIlmoyle, E To, Q Xu, V Hirsch-Reinshagen, ... Frontiers in neuroscience 14, 758, 2020 | 62 | 2020 |
Brain hypoxia is associated with neuroglial injury in humans post–cardiac arrest RL Hoiland, PN Ainslie, CL Wellington, J Cooper, S Stukas, S Thiara, ... Circulation research 129 (5), 583-597, 2021 | 59 | 2021 |
Clinical and neuropathological features of ALS/FTD with TIA1 mutations V Hirsch-Reinshagen, C Pottier, AM Nicholson, M Baker, GYR Hsiung, ... Acta neuropathologica communications 5, 1-13, 2017 | 49 | 2017 |
An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia J Fan, S Stukas, C Wong, J Chan, S May, N DeValle, ... Journal of Lipid Research 52 (9), 1605-1616, 2011 | 30 | 2011 |
Clinicopathologic correlations in a family with a TBK1 mutation presenting as primary progressive aphasia and primary lateral sclerosis V Hirsch-Reinshagen, OA Alfaify, GYR Hsiung, C Pottier, M Baker, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (7-8), 568-575, 2019 | 29 | 2019 |
Drusen in the peripheral retina of the Alzheimer's eye K Ukalovic, S Cao, S Lee, Q Tang, MF Beg, MV Sarunic, GYR Hsiung, ... Current Alzheimer Research 15 (8), 743-750, 2018 | 28 | 2018 |