Sean Lawler PhD
Sean Lawler PhD
Department of Pathology and Laboratory Medicine, Brown Cancer Center, Brown University
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MicroRNAs in cancer: biomarkers, functions and therapy
J Hayes, PP Peruzzi, S Lawler
Trends in molecular medicine 20 (8), 460-469, 2014
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma
B Kefas, J Godlewski, L Comeau, Y Li, R Abounader, M Hawkinson, J Lee, ...
Cancer research 68 (10), 3566-3572, 2008
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
J Godlewski, MO Nowicki, A Bronisz, S Williams, A Otsuki, G Nuovo, ...
Cancer research 68 (22), 9125-9130, 2008
Oncolytic viruses in cancer treatment: a review
SE Lawler, MC Speranza, CF Cho, EA Chiocca
JAMA oncology 3 (6), 841-849, 2017
Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor
R Ebner, RH Chen, L Shum, S Lawler, TF Zioncheck, A Lee, AR Lopez, ...
Science 260 (5112), 1344-1348, 1993
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
FL Ricklefs, Q Alayo, H Krenzlin, AB Mahmoud, MC Speranza, ...
Science advances 4 (3), eaar2766, 2018
MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells
J Godlewski, MO Nowicki, A Bronisz, G Nuovo, J Palatini, M De Lay, ...
Molecular cell 37 (5), 620-632, 2010
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
M Goedert, M Hasegawa, R Jakes, S Lawler, A Cuenda, P Cohen
FEBS letters 409 (1), 57-62, 1997
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
A Bronisz, J Godlewski, JA Wallace, AS Merchant, MO Nowicki, ...
Nature cell biology 14 (2), 159-167, 2012
Determination of type I receptor specificity by the type II receptors for TGF-β or activin
R Ebner, RH Chen, S Lawler, T Zioncheck, R Derynck
Science 262 (5135), 900-902, 1993
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro
S Lawler, Y Fleming, M Goedert, P Cohen
Current Biology 8 (25), 1387-1391, 1998
The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors
B Kefas, L Comeau, DH Floyd, O Seleverstov, J Godlewski, T Schmittgen, ...
Journal of Neuroscience 29 (48), 15161-15168, 2009
Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents
CF Cho, JM Wolfe, CM Fadzen, D Calligaris, K Hornburg, EA Chiocca, ...
Nature communications 8 (1), 15623, 2017
Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1
A Bronisz, Y Wang, MO Nowicki, P Peruzzi, KI Ansari, D Ogawa, L Balaj, ...
Cancer research 74 (3), 738-750, 2014
The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network
O Gavet, S Ozon, V Manceau, S Lawler, P Curmi, A Sobel
Journal of cell science 111 (22), 3333-3346, 1998
Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity
M Guerau-de-Arellano, KM Smith, J Godlewski, Y Liu, R Winger, ...
Brain 134 (12), 3578-3589, 2011
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors
CA Alvarez-Breckenridge, J Yu, R Price, J Wojton, J Pradarelli, H Mao, ...
Nature medicine 18 (12), 1827-1834, 2012
Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics
S Bergmann, SE Lawler, Y Qu, CM Fadzen, JM Wolfe, MS Regan, ...
Nature protocols 13 (12), 2827-2843, 2018
microRNA-451: A conditional switch controlling glioma cell proliferation and migration
J Godlewski, A Bronisz, MO Nowicki, EA Chiocca, S Lawler
Cell cycle 9 (14), 2814-2820, 2010
The type II transforming growth factor-β receptor autophosphorylates not only on serine and threonine but also on tyrosine residues
S Lawler, XH Feng, RH Chen, EM Maruoka, CW Turck, ...
Journal of Biological Chemistry 272 (23), 14850-14859, 1997
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