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Douglas Spitz
Douglas Spitz
Professor of Radiation Oncology, University of Iowa
Dirección de correo verificada de uiowa.edu
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A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
JR Erickson, AJ Mei-ling, X Guan, W Kutschke, J Yang, CV Oddis, ...
Cell 133 (3), 462-474, 2008
12242008
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
R Tao, MC Coleman, JD Pennington, O Ozden, SH Park, H Jiang, HS Kim, ...
Molecular cell 40 (6), 893-904, 2010
10092010
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
HS Kim, K Patel, K Muldoon-Jacobs, KS Bisht, N Aykin-Burns, ...
Cancer cell 17 (1), 41-52, 2010
9252010
Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology
DR Spitz, EI Azzam, J Jian Li, D Gius
Cancer and Metastasis Reviews 23, 311-322, 2004
8672004
An assay for superoxide dismutase activity in mammalian tissue homogenates
DR Spitz, LW Oberley
Analytical biochemistry 179 (1), 8-18, 1989
8611989
Lymph protects metastasizing melanoma cells from ferroptosis
JM Ubellacker, A Tasdogan, V Ramesh, B Shen, EC Mitchell, ...
Nature 585 (7823), 113-118, 2020
6382020
HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress
J Huot, F Houle, DR Spitz, J Landry
Cancer research 56 (2), 273-279, 1996
6251996
[61] Assay of superoxide dismutase activity in tumor tissue
LW Oberley, DR Spitz
Methods in enzymology 105, 457-464, 1984
5381984
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation
N Aykin-Burns, IM Ahmad, Y Zhu, LW Oberley, DR Spitz
Biochemical Journal 418 (1), 29-37, 2009
4872009
Superoxide mediates the actions of angiotensin II in the central nervous system
MC Zimmerman, E Lazartigues, JA Lang, P Sinnayah, IM Ahmad, ...
Circulation research 91 (11), 1038-1045, 2002
4592002
O2⋅− and H2O2-mediated disruption of Fe metabolism causes the differential susceptibility of NSCLC and GBM cancer cells to pharmacological ascorbate
JD Schoenfeld, ZA Sibenaller, KA Mapuskar, BA Wagner, ...
Cancer cell 31 (4), 487-500. e8, 2017
4582017
Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from α-particle-irradiated normal human fibroblast cultures
EI Azzam, SM De Toledo, DR Spitz, JB Little
Cancer research 62 (19), 5436-5442, 2002
4402002
Reactive oxygen species in normal and tumor stem cells
D Zhou, L Shao, DR Spitz
Advances in cancer research 122, 1-67, 2014
4142014
Glucose deprivation‐induced oxidative stress in human tumor cells: a fundamental defect in metabolism?
DR Spitz, JE Sim, LA Ridnour, SS Galoforo, YJ Lee
Annals of the New York Academy of Sciences 899 (1), 349-362, 2000
4122000
Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism
BG Allen, SK Bhatia, CM Anderson, JM Eichenberger-Gilmore, ...
Redox biology 2, 963-970, 2014
3872014
Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets …
R Polavarapu, DR Spitz, JE Sim, MH Follansbee, LW Oberley, ...
Hepatology 27 (5), 1317-1323, 1998
3651998
H2O2-induced O⨪ 2production by a non-phagocytic NAD (P) H oxidase causes oxidant injury
WG Li, FJ Miller, HJ Zhang, DR Spitz, LW Oberley, NL Weintraub
Journal of Biological Chemistry 276 (31), 29251-29256, 2001
3562001
Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses
G Guo, Y Yan-Sanders, BD Lyn-Cook, T Wang, D Tamae, J Ogi, ...
Molecular and cellular biology 23 (7), 2362-2378, 2003
3372003
Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats
H Gürer, H Özgünes, R Neal, DR Spitz, N Erçal
Toxicology 128 (3), 181-189, 1998
3331998
α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II
LF Dong, P Low, JC Dyason, XF Wang, L Prochazka, PK Witting, ...
Oncogene 27 (31), 4324-4335, 2008
3272008
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