Grace L. Guo
Grace L. Guo
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International patterns and trends in thyroid cancer incidence, 1973–2002
BA Kilfoy, T Zheng, TR Holford, X Han, MH Ward, A Sjodin, Y Zhang, ...
Cancer Causes & Control 20 (5), 525-531, 2009
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine
I Kim, SH Ahn, T Inagaki, M Choi, S Ito, GL Guo, SA Kliewer, FJ Gonzalez
Journal of lipid research 48 (12), 2664-2672, 2007
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis
G Lambert, MJA Amar, G Guo, HB Brewer, FJ Gonzalez, CJ Sinal
Journal of Biological Chemistry 278 (4), 2563-2570, 2003
Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway
JM Maher, MZ Dieter, LM Aleksunes, AL Slitt, G Guo, Y Tanaka, ...
Hepatology 46 (5), 1597-1610, 2007
Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity
GL Guo, G Lambert, M Negishi, JM Ward, HB Brewer, SA Kliewer, ...
Journal of Biological Chemistry 278 (46), 45062-45071, 2003
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice
M Wagner, P Fickert, G Zollner, A Fuchsbichler, D Silbert, O Tsybrovskyy, ...
Gastroenterology 125 (3), 825-838, 2003
Mechanism of tissue‐specific farnesoid X receptor in suppressing the expression of genes in bile‐acid synthesis in mice
B Kong, L Wang, JYL Chiang, Y Zhang, CD Klaassen, GL Guo
Hepatology 56 (3), 1034-1043, 2012
NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet
Y Tanaka, LM Aleksunes, RL Yeager, MA Gyamfi, N Esterly, GL Guo, ...
Journal of Pharmacology and Experimental Therapeutics 325 (2), 655-664, 2008
Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development
RRM Maran, A Thomas, M Roth, Z Sheng, N Esterly, D Pinson, X Gao, ...
Journal of Pharmacology and Experimental Therapeutics 328 (2), 469-477, 2009
Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis
T Li, M Matozel, S Boehme, B Kong, LM Nilsson, G Guo, E Ellis, ...
Hepatology 53 (3), 996-1006, 2011
Estrogen receptor α mediates 17α-ethynylestradiol causing hepatotoxicity
Y Yamamoto, R Moore, HA Hess, GL Guo, FJ Gonzalez, KS Korach, ...
Journal of Biological Chemistry 281 (24), 16625-16631, 2006
Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet
B Kong, JP Luyendyk, O Tawfik, GL Guo
Journal of Pharmacology and Experimental Therapeutics 328 (1), 116-122, 2009
Genome‐wide tissue‐specific farnesoid X receptor binding in mouse liver and intestine
AM Thomas, SN Hart, B Kong, J Fang, X Zhong, GL Guo
Hepatology 51 (4), 1410-1419, 2010
Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16α-carbonitrile is via interaction with pregnane X receptor
GL Guo, J Staudinger, K Ogura, CD Klaassen
Molecular pharmacology 61 (4), 832-839, 2002
Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity
H Kitada, M Miyata, T Nakamura, A Tozawa, W Honma, M Shimada, ...
Journal of Biological Chemistry 278 (20), 17838-17844, 2003
The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators
EK Pacyniak, X Cheng, ML Cunningham, K Crofton, CD Klaassen, ...
Toxicological sciences 97 (1), 94-102, 2007
The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A
X Ma, Y Shah, C Cheung, GL Guo, L Feigenbaum, KW Krausz, JR Idle, ...
Drug metabolism and disposition 35 (2), 194-200, 2007
Effects of FXR in foam-cell formation and atherosclerosis development
GL Guo, S Santamarina-Fojo, TE Akiyama, MJA Amar, BJ Paigen, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2006
Enhanced acetaminophen toxicity by activation of the pregnane X receptor
GL Guo, JS Moffit, CJ Nicol, JM Ward, LA Aleksunes, AL Slitt, SA Kliewer, ...
Toxicological Sciences 82 (2), 374-380, 2004
Rifaximin is a gut-specific human pregnane X receptor activator
X Ma, YM Shah, GL Guo, T Wang, KW Krausz, JR Idle, FJ Gonzalez
Journal of Pharmacology and Experimental Therapeutics 322 (1), 391-398, 2007
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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