Kai Yang
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mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
H Zeng, K Yang, C Cloer, G Neale, P Vogel, H Chi
Nature 499 (7459), 485-490, 2013
Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis
J Wei, L Long, K Yang, C Guy, S Shrestha, Z Chen, C Wu, P Vogel, ...
Autophagy enforces functional integrity of regulatory T cells by coupling …, 2016
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming
K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ...
Immunity 39 (6), 1043-1056, 2013
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses
S Shrestha, K Yang, C Guy, P Vogel, G Neale, H Chi
Nature Immunology 16 (2), 178-187, 2015
The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells
G Liu, K Yang, S Burns, S Shrestha, H Chi
Nature immunology 11 (11), 1047-1056, 2010
Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification
HX Shi, K Yang, X Liu, XY Liu, B Wei, YF Shan, LH Zhu, C Wang
Molecular and cellular biology 30 (10), 2424-2436, 2010
The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function
K Yang, G Neale, DR Green, W He, H Chi
Nature immunology 12 (9), 888-897, 2011
Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation
H Tan, K Yang, Y Li, T Shaw, Y Wang, DB Blanco, X Wang, JH Cho, ...
Immunity 46, 488, 2017
TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response
K Yang, HX Shi, XY Liu, YF Shan, B Wei, S Chen, C Wang
The Journal of Immunology 182 (6), 3782-3792, 2009
The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
C Xu, S Sun, T Johnson, R Qi, S Zhang, J Zhang, K Yang
Cell reports 35 (11), 109235, 2021
Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling
K Yang, DB Blanco, G Neale, P Vogel, J Avila, CB Clish, C Wu, ...
Nature 548 (7669), 602-606, 2017
mTOR and metabolic pathways in T cell quiescence and functional activation
K Yang, H Chi
Seminars in immunology 24 (6), 421-428, 2012
Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells
K Yang, H Shi, R Qi, S Sun, Y Tang, B Zhang, C Wang
Molecular biology of the cell 17 (3), 1461-1471, 2006
Tuberous sclerosis 1-dependent metabolic checkpoint controls development of dendritic cells
Y Wang, G Huang, H Zeng, K Yang, RF Lamb, H Chi
PNAS 110 (50), E4894-4903, 2013
Herpes virus proteins ICP0 and BICP0 can activate NF-κB by catalyzing IκBα ubiquitination
L Diao, B Zhang, J Fan, X Gao, S Sun, K Yang, D Xin, N Jin, Y Geng, ...
Cellular signalling 17 (2), 217-229, 2005
UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome
S Sun, Y Tang, X Lou, L Zhu, K Yang, B Zhang, H Shi, C Wang
The Journal of cell biology 178 (2), 231-244, 2007
Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs
S Shrestha, K Yang, J Wei, PWF Karmaus, G Neale, H Chi
Proc Natl Acad Sci U S A. 111 (41), 14858-14863, 2014
The TAK1-JNK cascade is required for IRF3 function in the innate immune response
B Zhang, M Li, L Chen, K Yang, Y Shan, L Zhu, S Sun, L Li, C Wang
Cell research 19 (4), 412-428, 2009
The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination
K Yang, J Zhu, S Sun, Y Tang, B Zhang, L Diao, C Wang
Biochemical and biophysical research communications 324 (1), 432-439, 2004
iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.
J Wu, J Yang, K Yang, H Wang, B Gorentla, J Shin, Y Qiu, LG Que, ...
J Clin Invest. 124 (4), 1685-1698, 2014
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