| Novel technologies for metabolomics: More for less P Miggiels, B Wouters, GJP van Westen, AC Dubbelman, T Hankemeier TrAC Trends in Analytical Chemistry 120, 115323, 2019 | 157 | 2019 |
| Pharmacokinetics and excretion of 14C-lenvatinib in patients with advanced solid tumors or lymphomas AC Dubbelman, H Rosing, C Nijenhuis, ADR Huitema, ... Investigational new drugs 33, 233-240, 2015 | 63 | 2015 |
| Pharmacokinetics and Excretion of 14C-Bendamustine in Patients with Relapsed or Refractory Malignancy AC Dubbelman, H Rosing, M Darwish, D D’Andrea, M Bond, E Hellriegel, ... Drugs in R&D 13, 17-28, 2013 | 46 | 2013 |
| Development and validation of LC–MS/MS assays for the quantification of bendamustine and its metabolites in human plasma and urine AC Dubbelman, M Tibben, H Rosing, A Gebretensae, L Nan, SH Gorman, ... Journal of Chromatography B 893, 92-100, 2012 | 40 | 2012 |
| Development and validation of LC–MS/MS assays for the quantification of E7080 and metabolites in various human biological matrices AC Dubbelman, H Rosing, B Thijssen, A Gebretensae, L Lucas, H Chen, ... Journal of Chromatography B 887, 25-34, 2012 | 37 | 2012 |
| Systematic evaluation of HILIC stationary phases for global metabolomics of human plasma F Hosseinkhani, L Huang, AC Dubbelman, F Guled, AC Harms, ... Metabolites 12 (2), 165, 2022 | 34 | 2022 |
| Mass balance study of [14C] eribulin in patients with advanced solid tumors AC Dubbelman, H Rosing, RS Jansen, M Mergui-Roelvink, ADR Huitema, ... Drug Metabolism and Disposition 40 (2), 313-321, 2012 | 30 | 2012 |
| Data-independent acquisition for the quantification and identification of metabolites in plasma T van der Laan, I Boom, J Maliepaard, AC Dubbelman, AC Harms, ... Metabolites 10 (12), 514, 2020 | 29 | 2020 |
| Mass spectrometric recommendations for Quan/Qual analysis using liquid-chromatography coupled to quadrupole time-of-flight mass spectrometry AC Dubbelman, F Cuyckens, L Dillen, G Gross, RJ Vreeken, ... Analytica Chimica Acta 1020, 62-75, 2018 | 24 | 2018 |
| Quantification of docetaxel and its metabolites in human plasma by liquid chromatography/tandem mass spectrometry J Hendrikx, AC Dubbelman, H Rosing, AH Schinkel, JHM Schellens, ... Rapid Communications in Mass Spectrometry 27 (17), 1925-1934, 2013 | 24 | 2013 |
| Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors AC Dubbelman, A Upthagrove, JH Beijnen, S Marchetti, E Tan, K Krone, ... Cancer chemotherapy and pharmacology 70, 653-663, 2012 | 23 | 2012 |
| Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison AC Dubbelman, CM Nijenhuis, RS Jansen, H Rosing, H Mizuo, ... Investigational new drugs 34, 300-318, 2016 | 22 | 2016 |
| Towards standards for human fecal sample preparation in targeted and untargeted lc-hrms studies F Hosseinkhani, AC Dubbelman, N Karu, AC Harms, T Hankemeier Metabolites 11 (6), 364, 2021 | 20 | 2021 |
| Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum T van der Laan, T Kloots, M Beekman, A Kindt, AC Dubbelman, A Harms, ... Scientific reports 9 (1), 12370, 2019 | 19 | 2019 |
| Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C] bendamustine AC Dubbelman, RS Jansen, H Rosing, M Darwish, E Hellriegel, ... Drug Metabolism and Disposition 40 (7), 1297-1307, 2012 | 16 | 2012 |
| Validation of high-performance liquid chromatography–tandem mass spectrometry assays for the quantification of eribulin (E7389) in various biological matrices AC Dubbelman, H Rosing, B Thijssen, L Lucas, W Copalu, J Wanders, ... Journal of Chromatography B 879 (15-16), 1149-1155, 2011 | 13 | 2011 |
| Systematic evaluation of commercially available ultra-high performance liquid chromatography columns for drug metabolite profiling: optimization of chromatographic peak capacity AC Dubbelman, F Cuyckens, L Dillen, G Gross, T Hankemeier, ... Journal of Chromatography A 1374, 122-133, 2014 | 11 | 2014 |
| High-throughput fractionation coupled to mass spectrometry for improved quantitation in metabolomics T van Der Laan, AC Dubbelman, K Duisters, A Kindt, AC Harms, ... Analytical Chemistry 92 (21), 14330-14338, 2020 | 10 | 2020 |
| Postcolumn infusion as a quality control tool for LC-MS-based analysis O González, AC Dubbelman, T Hankemeier Journal of the American Society for Mass Spectrometry 33 (6), 1077-1080, 2022 | 9 | 2022 |
| Fractionation platform for target identification using off-line directed two-dimensional chromatography, mass spectrometry and nuclear magnetic resonance T van der Laan, H Elfrink, F Azadi-Chegeni, AC Dubbelman, AC Harms, ... Analytica Chimica Acta 1142, 28-37, 2021 | 9 | 2021 |
Thomas HankemeierProfessor of Analytical Biosciences, Leiden UniversityVerified email at lacdr.leidenuniv.nl
