A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite KM Miranda, MG Espey, DA Wink Nitric Oxide 5 (1), 62-71, 2001 | 4388 | 2001 |
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues Q Chen, MG Espey, MC Krishna, JB Mitchell, CP Corpe, GR Buettner, ... Proceedings of the National Academy of Sciences 102 (38), 13604-13609, 2005 | 1320 | 2005 |
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice Q Chen, MG Espey, AY Sun, C Pooput, KL Kirk, MC Krishna, DB Khosh, ... Proceedings of the National Academy of Sciences 105 (32), 11105-11109, 2008 | 1085 | 2008 |
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo Q Chen, MG Espey, AY Sun, JH Lee, MC Krishna, E Shacter, PL Choyke, ... Proceedings of the National Academy of Sciences 104 (21), 8749-8754, 2007 | 848 | 2007 |
The emerging biology of the nitrite anion MT Gladwin, AN Schechter, DB Kim-Shapiro, RP Patel, N Hogg, S Shiva, ... Nature Chemical Biology 1 (6), 308-314, 2005 | 719 | 2005 |
Mechanisms of the antioxidant effects of nitric oxide DA Wink, KM Miranda, MG Espey, RM Pluta, SJ Hewett, C Colton, M Vitek, ... Antioxidants and redox signaling 3 (2), 203-213, 2001 | 479 | 2001 |
The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations LA Ridnour, DD Thomas, D Mancardi, MG Espey, KM Miranda, ... Walter de Gruyter 385 (1), 1-10, 2004 | 443 | 2004 |
Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects SJ Padayatty, AY Sun, Q Chen, MG Espey, J Drisko, M Levine PloS one 5 (7), e11414, 2010 | 426 | 2010 |
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation LJ Hofseth, S Saito, SP Hussain, MG Espey, KM Miranda, Y Araki, ... Proceedings of the national academy of sciences 100 (1), 143-148, 2003 | 426 | 2003 |
Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries M Levine, SJ Padayatty, MG Espey Advances in nutrition 2 (2), 78-88, 2011 | 421 | 2011 |
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1 LA Ridnour, JS Isenberg, MG Espey, DD Thomas, DD Roberts, DA Wink Proceedings of the National Academy of Sciences 102 (37), 13147-13152, 2005 | 406 | 2005 |
Role of oxygen gradients in shaping redox relationships between the human intestine and its microbiota MG Espey Free Radical Biology and Medicine 55, 130-140, 2013 | 388 | 2013 |
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling N Paolocci, WF Saavedra, KM Miranda, C Martignani, T Isoda, JM Hare, ... Proceedings of the National Academy of Sciences 98 (18), 10463-10468, 2001 | 360 | 2001 |
Hypoxic inducible factor 1α, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide DD Thomas, MG Espey, LA Ridnour, LJ Hofseth, D Mancardi, CC Harris, ... Proceedings of the National Academy of Sciences 101 (24), 8894-8899, 2004 | 348 | 2004 |
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system KM Miranda, N Paolocci, T Katori, DD Thomas, E Ford, MD Bartberger, ... Proceedings of the National Academy of Sciences 100 (16), 9196-9201, 2003 | 323 | 2003 |
Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner JS Isenberg, LA Ridnour, EM Perruccio, MG Espey, DA Wink, DD Roberts Proceedings of the National Academy of Sciences 102 (37), 13141-13146, 2005 | 299 | 2005 |
The biphasic nature of nitric oxide responses in tumor biology LA Ridnour, DD Thomas, S Donzelli, MG Espey, DD Roberts, DA Wink, ... Antioxidants & Redox Signaling 8 (7-8), 1329-1337, 2006 | 274 | 2006 |
Activated human microglia produce the excitotoxin quinolinic acid MG Espey, ON Chernyshev, JF Reinhard Jr, MAA Namboodiri, CA Colton Neuroreport 8 (2), 431-434, 1997 | 237 | 1997 |
Protein nitration is mediated by heme and free metals through Fenton-type chemistry: An alternative to the NO/O reaction DD Thomas, MG Espey, MP Vitek, KM Miranda, DA Wink Proceedings of the National Academy of Sciences 99 (20), 12691-12696, 2002 | 224 | 2002 |
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer MG Espey, P Chen, B Chalmers, J Drisko, AY Sun, M Levine, Q Chen Free Radical Biology and Medicine 50 (11), 1610-1619, 2011 | 219 | 2011 |