|A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite|
KM Miranda, MG Espey, DA Wink
Nitric Oxide 5 (1), 62-71, 2001
|Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues|
Q Chen, MG Espey, MC Krishna, JB Mitchell, CP Corpe, GR Buettner, ...
Proceedings of the National Academy of Sciences 102 (38), 13604-13609, 2005
|Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice|
Q Chen, MG Espey, AY Sun, C Pooput, KL Kirk, MC Krishna, DB Khosh, ...
Proceedings of the National Academy of Sciences 105 (32), 11105-11109, 2008
|Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo|
Q Chen, MG Espey, AY Sun, JH Lee, MC Krishna, E Shacter, PL Choyke, ...
Proceedings of the National Academy of Sciences 104 (21), 8749-8754, 2007
|The emerging biology of the nitrite anion|
MT Gladwin, AN Schechter, DB Kim-Shapiro, RP Patel, N Hogg, S Shiva, ...
Nature Chemical Biology 1 (6), 308-314, 2005
|Nitric oxide-induced cellular stress and p53 activation in chronic inflammation|
LJ Hofseth, S Saito, SP Hussain, MG Espey, KM Miranda, Y Araki, ...
Proceedings of the national academy of sciences 100 (1), 143-148, 2003
|Mechanisms of the antioxidant effects of nitric oxide|
DA Wink, KM Miranda, MG Espey, RM Pluta, SJ Hewett, C Colton, M Vitek, ...
Antioxidants and redox signaling 3 (2), 203-213, 2001
|The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations|
LA Ridnour, DD Thomas, D Mancardi, MG Espey, KM Miranda, ...
Biological chemistry 385 (1), 1-10, 2004
|Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1|
LA Ridnour, JS Isenberg, MG Espey, DD Thomas, DD Roberts, DA Wink
Proceedings of the National Academy of Sciences 102 (37), 13147-13152, 2005
|Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling|
N Paolocci, WF Saavedra, KM Miranda, C Martignani, T Isoda, JM Hare, ...
Proceedings of the National Academy of Sciences 98 (18), 10463-10468, 2001
|Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects|
SJ Padayatty, AY Sun, Q Chen, MG Espey, J Drisko, M Levine
PloS one 5 (7), e11414, 2010
|Hypoxic inducible factor 1α, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide|
DD Thomas, MG Espey, LA Ridnour, LJ Hofseth, D Mancardi, CC Harris, ...
Proceedings of the National Academy of Sciences 101 (24), 8894-8899, 2004
|A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system|
KM Miranda, N Paolocci, T Katori, DD Thomas, E Ford, MD Bartberger, ...
Proceedings of the National Academy of Sciences 100 (16), 9196-9201, 2003
|Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries|
M Levine, SJ Padayatty, MG Espey
Advances in nutrition 2 (2), 78-88, 2011
|Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner|
JS Isenberg, LA Ridnour, EM Perruccio, MG Espey, DA Wink, DD Roberts
Proceedings of the National Academy of Sciences 102 (37), 13141-13146, 2005
|Role of oxygen gradients in shaping redox relationships between the human intestine and its microbiota|
Free Radical Biology and Medicine 55, 130-140, 2013
|The biphasic nature of nitric oxide responses in tumor biology|
LA Ridnour, DD Thomas, S Donzelli, MG Espey, DD Roberts, DA Wink, ...
Antioxidants & Redox Signaling 8 (7-8), 1329-1337, 2006
|Protein nitration is mediated by heme and free metals through Fenton-type chemistry: An alternative to the NO/O reaction|
DD Thomas, MG Espey, MP Vitek, KM Miranda, DA Wink
Proceedings of the National Academy of Sciences 99 (20), 12691-12696, 2002
|Activated human microglia produce the excitotoxin quinolinic acid|
MG Espey, ON Chernyshev, JF Reinhard Jr, MAA Namboodiri, CA Colton
Neuroreport 8 (2), 431-434, 1997
|Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide|
MG Espey, DD Thomas, KM Miranda, DA Wink
Proceedings of the National Academy of Sciences 99 (17), 11127-11132, 2002