Atopic dermatitis is an IL-13–dominant disease with greater molecular heterogeneity compared to psoriasis LC Tsoi, E Rodriguez, F Degenhardt, H Baurecht, U Wehkamp, N Volks, ... Journal of Investigative Dermatology 139 (7), 1480-1489, 2019 | 443 | 2019 |
Psoriasis: a mixed autoimmune and autoinflammatory disease Y Liang, MK Sarkar, LC Tsoi, JE Gudjonsson Current opinion in immunology 49, 1-8, 2017 | 301 | 2017 |
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin LC Tsoi, MK Iyer, PE Stuart, WR Swindell, JE Gudjonsson, T Tejasvi, ... Genome biology 16, 1-15, 2015 | 253 | 2015 |
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa MK Sarkar, GA Hile, LC Tsoi, X Xing, J Liu, Y Liang, CC Berthier, ... Annals of the rheumatic diseases 77 (11), 1653-1664, 2018 | 249 | 2018 |
Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses LC Tsoi, E Rodriguez, D Stölzl, U Wehkamp, J Sun, S Gerdes, MK Sarkar, ... Journal of Allergy and Clinical Immunology 145 (5), 1406-1415, 2020 | 167 | 2020 |
Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis WR Swindell, KA Michaels, AJ Sutter, D Diaconu, Y Fritz, X Xing, ... Genome medicine 9, 1-21, 2017 | 167 | 2017 |
IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus S Shao, LC Tsoi, MK Sarkar, X Xing, K Xue, R Uppala, CC Berthier, ... Science translational medicine 11 (511), eaav7561, 2019 | 140 | 2019 |
A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases Y Liang, LC Tsoi, X Xing, MA Beamer, WR Swindell, MK Sarkar, ... Nature immunology 18 (2), 152-160, 2017 | 127 | 2017 |
IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, ... Scientific reports 7 (1), 13831, 2017 | 118 | 2017 |
RNA-Seq analysis of IL-1B and IL-36 responses in epidermal keratinocytes identifies a shared MyD88-dependent gene signature WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, ... Frontiers in immunology 9, 80, 2018 | 110 | 2018 |
Lupus skin is primed for IL-6 inflammatory responses through a keratinocyte-mediated autocrine type I interferon loop JN Stannard, TJ Reed, E Myers, L Lowe, MK Sarkar, X Xing, ... Journal of Investigative Dermatology 137 (1), 115-122, 2017 | 109 | 2017 |
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis F Ma, O Plazyo, AC Billi, LC Tsoi, X Xing, R Wasikowski, ... Nature communications 14 (1), 3455, 2023 | 106 | 2023 |
Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance WR Swindell, HA Remmer, MK Sarkar, X Xing, DH Barnes, L Wolterink, ... Genome medicine 7, 1-22, 2015 | 100 | 2015 |
Cross-disease transcriptomics: unique IL-17A signaling in psoriasis lesions and an autoimmune PBMC signature WR Swindell, MK Sarkar, Y Liang, X Xing, JE Gudjonsson Journal of Investigative Dermatology 136 (9), 1820-1830, 2016 | 78 | 2016 |
Hepatocytes are protected by herb Phyllanthus niruri protein isolate against thioacetamide toxicity MK Sarkar, PC Sil Pathophysiology 14 (2), 113-120, 2007 | 74 | 2007 |
Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era JE Swindell, W.R. , Stuart, P.E. , Sarkar, M.K. , Voorhees, J.J. , Elder, J ... BMC Medical Genomics 7 (1), 2014 | 68 | 2014 |
The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity AC Billi, M Gharaee-Kermani, J Fullmer, LC Tsoi, BD Hill, D Gruszka, ... JCI insight 4 (8), 2019 | 67 | 2019 |
Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri MK Sarkar, PC Sil Toxicology in vitro 24 (6), 1711-1719, 2010 | 66 | 2010 |
Six-transmembrane epithelial antigens of the prostate comprise a novel inflammatory nexus in patients with pustular skin disorders Y Liang, X Xing, MA Beamer, WR Swindell, MK Sarkar, LW Roberts, ... Journal of Allergy and Clinical Immunology 139 (4), 1217-1227, 2017 | 63 | 2017 |
Hypersensitive IFN responses in lupus keratinocytes reveal key mechanistic determinants in cutaneous lupus LC Tsoi, GA Hile, CC Berthier, MK Sarkar, TJ Reed, J Liu, R Uppala, ... The Journal of Immunology 202 (7), 2121-2130, 2019 | 61 | 2019 |