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Andrea D. Olmstead
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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic
T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, ...
Nature 605 (7909), 340-348, 2022
1702022
Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents
AD Olmstead, W Knecht, I Lazarov, SB Dixit, F Jean
PLoS pathogens 8 (1), e1002468, 2012
1022012
Phylogenetic clustering of hepatitis C virus among people who inject drugs in Vancouver, Canada
B Jacka, T Applegate, M Krajden, A Olmstead, PR Harrigan, BDL Marshall, ...
Hepatology 60 (5), 1571-1580, 2014
842014
Hijacking of lipid droplets by hepatitis C, dengue and zika viruses—from viral protein moonlighting to extracellular release
APM Cloherty, AD Olmstead, CMS Ribeiro, F Jean
International journal of molecular sciences 21 (21), 7901, 2020
652020
The spread of hepatitis C virus genotype 1a in North America: a retrospective phylogenetic study
JB Joy, RM McCloskey, T Nguyen, RH Liang, Y Khudyakov, A Olmstead, ...
The Lancet Infectious Diseases 16 (6), 698-702, 2016
612016
Methamphetamine injecting is associated with phylogenetic clustering of hepatitis C virus infection among street-involved youth in Vancouver, Canada
EB Cunningham, B Jacka, K DeBeck, TL Applegate, PR Harrigan, ...
Drug and alcohol dependence 152, 272-276, 2015
422015
Treatment-induced viral cure of hepatitis C virus-infected patients involves a dynamic interplay among three important molecular players in lipid homeostasis: circulating …
A Hyrina, AD Olmstead, P Steven, M Krajden, E Tam, F Jean
EBioMedicine 23, 68-78, 2017
412017
A molecular phylogenetics-based approach for identifying recent hepatitis C virus transmission events
AD Olmstead, JB Joy, V Montoya, I Luo, AFY Poon, B Jacka, F Lamoury, ...
Infection, Genetics and Evolution 33, 101-109, 2015
352015
Transmission of hepatitis C virus infection among younger and older people who inject drugs in Vancouver, Canada
B Jacka, T Applegate, AF Poon, J Raghwani, PR Harrigan, K DeBeck, ...
Journal of hepatology 64 (6), 1247-1255, 2016
322016
Differentiation of acute from chronic hepatitis C virus infection by nonstructural 5B deep sequencing: A population‐level tool for incidence estimation
V Montoya, AD Olmstead, NZ Janjua, P Tang, J Grebely, D Cook, ...
Hepatology 61 (6), 1842-1850, 2015
242015
Photodynamic and contact killing polymeric fabric coating for bacteria and SARS-CoV-2
T Wright, M Vlok, T Shapira, AD Olmstead, F Jean, MO Wolf
ACS Applied Materials & Interfaces 14 (1), 49-56, 2022
232022
Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing
V Montoya, A Olmstead, P Tang, D Cook, N Janjua, J Grebely, B Jacka, ...
Infection, Genetics and Evolution 43, 329-337, 2016
222016
A novel highly potent inhibitor of TMPRSS2-like proteases blocks SARS-CoV-2 variants of concern and is broadly protective against infection and mortality in mice
T Shapira, IA Monreal, SP Dion, M Jager, A Désilets, AD Olmstead, ...
bioRxiv, 2021.05. 03.442520, 2021
182021
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics
J Pérez-Vargas, T Shapira, AD Olmstead, I Villanueva, CAH Thompson, ...
Antiviral research 209, 105484, 2023
162023
Prevalence of human immunodeficiency virus-1 integrase strand transfer inhibitor resistance in British Columbia, Canada between 2009 and 2016: a longitudinal analysis
K Kamelian, KJ Lepik, W Chau, B Yip, WW Zhang, VD Lima, MA Robbins, ...
Open forum infectious diseases 6 (3), ofz060, 2019
152019
DEEMD: Drug Efficacy Estimation against SARS-CoV-2 based on cell Morphology with Deep multiple instance learning
MS Saberian, KP Moriarty, AD Olmstead, C Hallgrimson, F Jean, IR Nabi, ...
IEEE Transactions on Medical Imaging 41 (11), 3128-3145, 2022
142022
A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity
A Khong, R Forestieri, DE Williams, BO Patrick, A Olmstead, V Svinti, ...
PloS one 7 (6), e39621, 2012
132012
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants
J Pérez-Vargas, LJ Worrall, AD Olmstead, AT Ton, J Lee, I Villanueva, ...
Emerging microbes & infections 12 (2), 2246594, 2023
92023
Phylogenetic surveillance of travel-related Zika virus infections through whole-genome sequencing methods
K Kamelian, V Montoya, A Olmstead, W Dong, R Harrigan, M Morshed, ...
Scientific Reports 9 (1), 16433, 2019
92019
A systematic, deep sequencing-based methodology for identification of mixed-genotype hepatitis C virus infections
AD Olmstead, V Montoya, CK Chui, W Dong, JB Joy, V Tai, AFY Poon, ...
Infection, Genetics and Evolution 69, 76-84, 2019
92019
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Articles 1–20