A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, ... Nature 605 (7909), 340-348, 2022 | 170 | 2022 |
Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents AD Olmstead, W Knecht, I Lazarov, SB Dixit, F Jean PLoS pathogens 8 (1), e1002468, 2012 | 102 | 2012 |
Phylogenetic clustering of hepatitis C virus among people who inject drugs in Vancouver, Canada B Jacka, T Applegate, M Krajden, A Olmstead, PR Harrigan, BDL Marshall, ... Hepatology 60 (5), 1571-1580, 2014 | 84 | 2014 |
Hijacking of lipid droplets by hepatitis C, dengue and zika viruses—from viral protein moonlighting to extracellular release APM Cloherty, AD Olmstead, CMS Ribeiro, F Jean International journal of molecular sciences 21 (21), 7901, 2020 | 65 | 2020 |
The spread of hepatitis C virus genotype 1a in North America: a retrospective phylogenetic study JB Joy, RM McCloskey, T Nguyen, RH Liang, Y Khudyakov, A Olmstead, ... The Lancet Infectious Diseases 16 (6), 698-702, 2016 | 61 | 2016 |
Methamphetamine injecting is associated with phylogenetic clustering of hepatitis C virus infection among street-involved youth in Vancouver, Canada EB Cunningham, B Jacka, K DeBeck, TL Applegate, PR Harrigan, ... Drug and alcohol dependence 152, 272-276, 2015 | 42 | 2015 |
Treatment-induced viral cure of hepatitis C virus-infected patients involves a dynamic interplay among three important molecular players in lipid homeostasis: circulating … A Hyrina, AD Olmstead, P Steven, M Krajden, E Tam, F Jean EBioMedicine 23, 68-78, 2017 | 41 | 2017 |
A molecular phylogenetics-based approach for identifying recent hepatitis C virus transmission events AD Olmstead, JB Joy, V Montoya, I Luo, AFY Poon, B Jacka, F Lamoury, ... Infection, Genetics and Evolution 33, 101-109, 2015 | 35 | 2015 |
Transmission of hepatitis C virus infection among younger and older people who inject drugs in Vancouver, Canada B Jacka, T Applegate, AF Poon, J Raghwani, PR Harrigan, K DeBeck, ... Journal of hepatology 64 (6), 1247-1255, 2016 | 32 | 2016 |
Differentiation of acute from chronic hepatitis C virus infection by nonstructural 5B deep sequencing: A population‐level tool for incidence estimation V Montoya, AD Olmstead, NZ Janjua, P Tang, J Grebely, D Cook, ... Hepatology 61 (6), 1842-1850, 2015 | 24 | 2015 |
Photodynamic and contact killing polymeric fabric coating for bacteria and SARS-CoV-2 T Wright, M Vlok, T Shapira, AD Olmstead, F Jean, MO Wolf ACS Applied Materials & Interfaces 14 (1), 49-56, 2022 | 23 | 2022 |
Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing V Montoya, A Olmstead, P Tang, D Cook, N Janjua, J Grebely, B Jacka, ... Infection, Genetics and Evolution 43, 329-337, 2016 | 22 | 2016 |
A novel highly potent inhibitor of TMPRSS2-like proteases blocks SARS-CoV-2 variants of concern and is broadly protective against infection and mortality in mice T Shapira, IA Monreal, SP Dion, M Jager, A Désilets, AD Olmstead, ... bioRxiv, 2021.05. 03.442520, 2021 | 18 | 2021 |
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics J Pérez-Vargas, T Shapira, AD Olmstead, I Villanueva, CAH Thompson, ... Antiviral research 209, 105484, 2023 | 16 | 2023 |
Prevalence of human immunodeficiency virus-1 integrase strand transfer inhibitor resistance in British Columbia, Canada between 2009 and 2016: a longitudinal analysis K Kamelian, KJ Lepik, W Chau, B Yip, WW Zhang, VD Lima, MA Robbins, ... Open forum infectious diseases 6 (3), ofz060, 2019 | 15 | 2019 |
DEEMD: Drug Efficacy Estimation against SARS-CoV-2 based on cell Morphology with Deep multiple instance learning MS Saberian, KP Moriarty, AD Olmstead, C Hallgrimson, F Jean, IR Nabi, ... IEEE Transactions on Medical Imaging 41 (11), 3128-3145, 2022 | 14 | 2022 |
A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity A Khong, R Forestieri, DE Williams, BO Patrick, A Olmstead, V Svinti, ... PloS one 7 (6), e39621, 2012 | 13 | 2012 |
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants J Pérez-Vargas, LJ Worrall, AD Olmstead, AT Ton, J Lee, I Villanueva, ... Emerging microbes & infections 12 (2), 2246594, 2023 | 9 | 2023 |
Phylogenetic surveillance of travel-related Zika virus infections through whole-genome sequencing methods K Kamelian, V Montoya, A Olmstead, W Dong, R Harrigan, M Morshed, ... Scientific Reports 9 (1), 16433, 2019 | 9 | 2019 |
A systematic, deep sequencing-based methodology for identification of mixed-genotype hepatitis C virus infections AD Olmstead, V Montoya, CK Chui, W Dong, JB Joy, V Tai, AFY Poon, ... Infection, Genetics and Evolution 69, 76-84, 2019 | 9 | 2019 |