A draft genome of Yersinia pestis from victims of the Black Death KI Bos, VJ Schuenemann, GB Golding, HA Burbano, N Waglechner, ... Nature 478 (7370), 506-510, 2011 | 909 | 2011 |
Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in … JB McPhee, S Lewenza, REW Hancock Molecular microbiology 50 (1), 205-217, 2003 | 531 | 2003 |
Adaptive Resistance to the “Last Hope” Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory … L Fernández, WJ Gooderham, M Bains, JB McPhee, I Wiegand, ... Antimicrobial agents and chemotherapy 54 (8), 3372-3382, 2010 | 413 | 2010 |
Function and therapeutic potential of host defence peptides JB Mcphee, REW Hancock Journal of peptide science: an official publication of the European Peptide …, 2005 | 273 | 2005 |
Contribution of the PhoP-PhoQ and PmrA-PmrB Two-Component Regulatory Systems to Mg2+-Induced Gene Regulation in Pseudomonas aeruginosa JB McPhee, M Bains, G Winsor, S Lewenza, A Kwasnicka, MD Brazas, ... Journal of bacteriology 188 (11), 3995-4006, 2006 | 264 | 2006 |
Defective NOD 2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance E Denou, K Lolmčde, L Garidou, C Pomie, C Chabo, TC Lau, ... EMBO molecular medicine 7 (3), 259-274, 2015 | 195 | 2015 |
Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes S Lewenza, RK Falsafi, G Winsor, WJ Gooderham, JB McPhee, ... Genome research 15 (4), 583-589, 2005 | 195 | 2005 |
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis CLN Small, SA Reid-Yu, JB McPhee, BK Coombes Nature communications 4 (1), 1957, 2013 | 186 | 2013 |
Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides A Clements, D Tull, AW Jenney, JL Farn, SH Kim, RE Bishop, JB McPhee, ... Journal of Biological Chemistry 282 (21), 15569-15577, 2007 | 152 | 2007 |
The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa WJ Gooderham, SL Gellatly, F Sanschagrin, JB McPhee, M Bains, ... Microbiology 155 (3), 699-711, 2009 | 128 | 2009 |
Design of host defence peptides for antimicrobial and immunity enhancing activities JB McPhee, MG Scott, REW Hancock Combinatorial chemistry & high throughput screening 8 (3), 257-272, 2005 | 105 | 2005 |
Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation JB McPhee, JD Schertzer Clinical science 129 (12), 1083-1096, 2015 | 103 | 2015 |
Delineation of Regions of the Yersinia YopM Protein Required for Interaction with the RSK1 and PRK2 Host Kinases and Their Requirement for Interleukin-10 … JB McPhee, P Mena, JB Bliska Infection and immunity 78 (8), 3529-3539, 2010 | 103 | 2010 |
L-asparaginase II produced by Salmonella typhimurium inhibits T cell responses and mediates virulence AL Kullas, M McClelland, HJ Yang, JW Tam, AM Torres, S Porwollik, ... Cell host & microbe 12 (6), 791-798, 2012 | 91 | 2012 |
Induction by cationic antimicrobial peptides and involvement in intrinsic polymyxin and antimicrobial peptide resistance, biofilm formation, and swarming motility of PsrA in … WJ Gooderham, M Bains, JB McPhee, I Wiegand, REW Hancock Journal of bacteriology 190 (16), 5624-5634, 2008 | 90 | 2008 |
Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn's disease-associated adherent-invasive Escherichia coli JB McPhee, CL Small, SA Reid-Yu, JR Brannon, H Le Moual, ... Infection and immunity 82 (8), 3383-3393, 2014 | 76 | 2014 |
The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel JB McPhee, S Tamber, M Bains, E Maier, S Gellatly, A Lo, R Benz, ... FEMS microbiology letters 296 (2), 241-247, 2009 | 72 | 2009 |
Acute infectious gastroenteritis potentiates a Crohn's disease pathobiont to fuel ongoing inflammation in the post-infectious period CL Small, L Xing, JB McPhee, HT Law, BK Coombes PLoS Pathogens 12 (10), e1005907, 2016 | 53 | 2016 |
Uncovering an important role for YopJ in the inhibition of caspase-1 in activated macrophages and promoting Yersinia pseudotuberculosis virulence TJ Schoberle, LK Chung, JB McPhee, B Bogin, JB Bliska Infection and immunity 84 (4), 1062-1072, 2016 | 43 | 2016 |
Interleukin-10 induction is an important virulence function of the Yersinia pseudotuberculosis type III effector YopM JB McPhee, P Mena, Y Zhang, JB Bliska Infection and immunity 80 (7), 2519-2527, 2012 | 42 | 2012 |