Joseph McPhee
Joseph McPhee
Toronto Metropolitan University
Verified email at - Homepage
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A draft genome of Yersinia pestis from victims of the Black Death
KI Bos, VJ Schuenemann, GB Golding, HA Burbano, N Waglechner, ...
Nature 478 (7370), 506-510, 2011
Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in …
JB McPhee, S Lewenza, REW Hancock
Molecular microbiology 50 (1), 205-217, 2003
Adaptive Resistance to the “Last Hope” Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory …
L Fernández, WJ Gooderham, M Bains, JB McPhee, I Wiegand, ...
Antimicrobial agents and chemotherapy 54 (8), 3372-3382, 2010
Function and therapeutic potential of host defence peptides
JB Mcphee, REW Hancock
Journal of peptide science: an official publication of the European Peptide …, 2005
Contribution of the PhoP-PhoQ and PmrA-PmrB Two-Component Regulatory Systems to Mg2+-Induced Gene Regulation in Pseudomonas aeruginosa
JB McPhee, M Bains, G Winsor, S Lewenza, A Kwasnicka, MD Brazas, ...
Journal of bacteriology 188 (11), 3995-4006, 2006
Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes
S Lewenza, RK Falsafi, G Winsor, WJ Gooderham, JB McPhee, ...
Genome research 15 (4), 583-589, 2005
Defective NOD 2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance
E Denou, K Lolmčde, L Garidou, C Pomie, C Chabo, TC Lau, ...
EMBO molecular medicine 7 (3), 259-274, 2015
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis
CLN Small, SA Reid-Yu, JB McPhee, BK Coombes
Nature communications 4 (1), 1957, 2013
Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides
A Clements, D Tull, AW Jenney, JL Farn, SH Kim, RE Bishop, JB McPhee, ...
Journal of Biological Chemistry 282 (21), 15569-15577, 2007
The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa
WJ Gooderham, SL Gellatly, F Sanschagrin, JB McPhee, M Bains, ...
Microbiology 155 (3), 699-711, 2009
Design of host defence peptides for antimicrobial and immunity enhancing activities
JB McPhee, MG Scott, REW Hancock
Combinatorial chemistry & high throughput screening 8 (3), 257-272, 2005
Delineation of Regions of the Yersinia YopM Protein Required for Interaction with the RSK1 and PRK2 Host Kinases and Their Requirement for Interleukin-10 …
JB McPhee, P Mena, JB Bliska
Infection and immunity 78 (8), 3529-3539, 2010
Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation
JB McPhee, JD Schertzer
Clinical science 129 (12), 1083-1096, 2015
L-asparaginase II produced by Salmonella typhimurium inhibits T cell responses and mediates virulence
AL Kullas, M McClelland, HJ Yang, JW Tam, AM Torres, S Porwollik, ...
Cell host & microbe 12 (6), 791-798, 2012
Induction by cationic antimicrobial peptides and involvement in intrinsic polymyxin and antimicrobial peptide resistance, biofilm formation, and swarming motility of PsrA in …
WJ Gooderham, M Bains, JB McPhee, I Wiegand, REW Hancock
Journal of bacteriology 190 (16), 5624-5634, 2008
The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel
JB McPhee, S Tamber, M Bains, E Maier, S Gellatly, A Lo, R Benz, ...
FEMS microbiology letters 296 (2), 241-247, 2009
Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn's disease-associated adherent-invasive Escherichia coli
JB McPhee, CL Small, SA Reid-Yu, JR Brannon, H Le Moual, ...
Infection and immunity 82 (8), 3383-3393, 2014
Acute infectious gastroenteritis potentiates a Crohn's disease pathobiont to fuel ongoing inflammation in the post-infectious period
CL Small, L Xing, JB McPhee, HT Law, BK Coombes
PLoS Pathogens 12 (10), e1005907, 2016
Interleukin-10 induction is an important virulence function of the Yersinia pseudotuberculosis type III effector YopM
JB McPhee, P Mena, Y Zhang, JB Bliska
Infection and immunity 80 (7), 2519-2527, 2012
Uncovering an important role for YopJ in the inhibition of caspase-1 in activated macrophages and promoting Yersinia pseudotuberculosis virulence
TJ Schoberle, LK Chung, JB McPhee, B Bogin, JB Bliska
Infection and immunity 84 (4), 1062-1072, 2016
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