Neil Fairweather
Neil Fairweather
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The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome
M Sebaihia, BW Wren, P Mullany, NF Fairweather, N Minton, R Stabler, ...
Nature genetics 38 (7), 779-786, 2006
Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts
TD Lawley, S Clare, AW Walker, D Goulding, RA Stabler, N Croucher, ...
Infection and immunity 77 (9), 3661-3669, 2009
Structure of Bordetella pertussis virulence factor P. 69 pertactin
P Emsley, IG Charles, NF Fairweather, NW Isaacs
Nature Publishing Group 381 (6577), 90-92, 1996
Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells
E Leininger, M Roberts, JG Kenimer, IG Charles, N Fairweather, ...
Proceedings of the National Academy of Sciences 88 (2), 345-349, 1991
The Clostridium difficile spo0A gene is a persistence and transmission factor
LJ Deakin, S Clare, RP Fagan, LF Dawson, DJ Pickard, MR West, ...
Infection and immunity 80 (8), 2704-2711, 2012
Expression of tetanus toxin fragment C in tobacco chloroplasts
JS Tregoning, P Nixon, H Kuroda, Z Svab, S Clare, F Bowe, ...
Nucleic acids research 31 (4), 1174-1179, 2003
Biogenesis and functions of bacterial S-layers
RP Fagan, NF Fairweather
Nature Reviews Microbiology 12 (3), 211-222, 2014
Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine
SN Chatfield, IG Charles, AJ Makoff, MD Oxer, G Dougan, D Pickard, ...
Nature Biotechnology 10 (8), 888-892, 1992
Bacterial spores as vaccine vehicles
LH Duc, HA Hong, N Fairweather, E Ricca, SM Cutting
Infection and immunity 71 (5), 2810-2818, 2003
Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues
E Calabi, F Calabi, AD Phillips, NF Fairweather
Infection and immunity 70 (10), 5770-5778, 2002
Clostridium difficile has two parallel and essential Sec secretion systems
RP Fagan, NF Fairweather
Journal of Biological Chemistry 286 (31), 27483-27493, 2011
Molecular characterization of the surface layer proteins from Clostridium difficile
E Calabi, S Ward, B Wren, T Paxton, M Panico, H Morris, A Dell, ...
Molecular microbiology 40 (5), 1187-1199, 2001
Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against …
DM Yang, N Fairweather, LL Button, WR McMaster, LP Kahl, FY Liew
The Journal of Immunology 145 (7), 2281-2285, 1990
Molecular cloning and characterization of protective outer membrane protein P. 69 from Bordetella pertussis
IG Charles, G Dougan, D Pickard, S Chatfield, M Smith, P Novotny, ...
Proceedings of the National Academy of Sciences 86 (10), 3554-3558, 1989
Expression of tetanus toxin fragment C in E. coli: high level expression by removing rare codons
AJ Makoff, MD Oxer, MA Romanos, NF Fairweather, S Ballantine
Nucleic acids research 17 (24), 10191-10202, 1989
The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin
C Fotinou, P Emsley, I Black, H Ando, H Ishida, M Kiso, KA Sinha, ...
Journal of Biological Chemistry 276 (34), 32274-32281, 2001
Protein Structure and Folding-The Crystal Structure of Tetanus Toxin Hc Fragment Complexed with a Synthetic GT1b Analogue Suggests Cross-linking between Ganglioside Receptors …
C Fotinou, P Emsley, I Black, H Ando, H Ishida, M Kiso, KA Sinha, ...
Journal of Biological Chemistry 276 (34), 32274-32281, 2001
The complete nucleotide sequence of tetanus toxin
NF Fairweather, VA Lyness
Nucleic acids research 14 (19), 7809-7812, 1986
Isolation and characterisation of a strain carrying a conditional lethal mutation in the cou gene of Escherichia coli K12
E Orr, NF Fairweather, IB Holland, RH Pritchard
Molecular and General Genetics MGG 177 (1), 103-112, 1979
The structures of the HC fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding
P Emsley, C Fotinou, I Black, NF Fairweather, IG Charles, C Watts, ...
Journal of Biological Chemistry 275 (12), 8889-8894, 2000
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