| Clinical features of hepatocellular carcinoma with extrahepatic metastases M Natsuizaka, T Omura, T Akaike, Y Kuwata, K Yamazaki, T Sato, ... Journal of gastroenterology and hepatology 20 (11), 1781-1787, 2005 | 572 | 2005 |
| Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma M Natsuizaka, KA Whelan, S Kagawa, K Tanaka, V Giroux, ... Nature communications 8 (1), 1758, 2017 | 204 | 2017 |
| Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture J Kalabis, GS Wong, ME Vega, M Natsuizaka, ES Robertson, M Herlyn, ... Nature protocols 7 (2), 235-246, 2012 | 189 | 2012 |
| Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors S Ohashi, M Natsuizaka, GS Wong, CZ Michaylira, KD Grugan, DB Stairs, ... Cancer research 70 (10), 4174-4184, 2010 | 174 | 2010 |
| NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network S Ohashi, M Natsuizaka, Y Yashiro–Ohtani, RA Kalman, M Nakagawa, ... Gastroenterology 139 (6), 2113-2123, 2010 | 153 | 2010 |
| Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis JJ Lee, M Natsuizaka, S Ohashi, GS Wong, M Takaoka, CZ Michaylira, ... Carcinogenesis 31 (3), 427-434, 2010 | 144 | 2010 |
| Efficacy and safety of daclatasvir and asunaprevir combination therapy in chronic hemodialysis patients with chronic hepatitis C G Suda, M Kudo, A Nagasaka, K Furuya, Y Yamamoto, T Kobayashi, ... Journal of gastroenterology 51, 733-740, 2016 | 139 | 2016 |
| A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors S Ohashi, M Natsuizaka, S Naganuma, S Kagawa, S Kimura, H Itoh, ... Cancer research 71 (21), 6836-6847, 2011 | 129 | 2011 |
| 8‐Hydroxy‐2′‐deoxy‐guanosine is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection M Chuma, S Hige, M Nakanishi, K Ogawa, M Natsuizaka, Y Yamamoto, ... Journal of gastroenterology and hepatology 23 (9), 1431-1436, 2008 | 99 | 2008 |
| L‐carnitine suppresses loss of skeletal muscle mass in patients with liver cirrhosis M Ohara, K Ogawa, G Suda, M Kimura, O Maehara, T Shimazaki, ... Hepatology communications 2 (8), 910-922, 2018 | 98 | 2018 |
| Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia M Natsuizaka, M Ozasa, S Darmanin, M Miyamoto, S Kondo, S Kamada, ... Experimental cell research 313 (15), 3337-3348, 2007 | 95 | 2007 |
| IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment M Natsuizaka, H Kinugasa, S Kagawa, KA Whelan, S Naganuma, ... American journal of cancer research 4 (1), 29, 2014 | 93 | 2014 |
| Insulin-like growth factor-binding protein-3 promotes transforming growth factor-β1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells M Natsuizaka, S Ohashi, GS Wong, A Ahmadi, RA Kalman, D Budo, ... Carcinogenesis 31 (8), 1344-1353, 2010 | 91 | 2010 |
| Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance KA Whelan, PM Chandramouleeswaran, K Tanaka, M Natsuizaka, ... Oncogene 36 (34), 4843-4858, 2017 | 89 | 2017 |
| Fibroblast growth factor-2–mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma O Maehara, G Suda, M Natsuizaka, S Ohnishi, Y Komatsu, F Sato, ... Carcinogenesis 38 (11), 1073-1083, 2017 | 88 | 2017 |
| Mitochondrial SOD2 regulates epithelial–mesenchymal transition and cell populations defined by differential CD44 expression H Kinugasa, KA Whelan, K Tanaka, M Natsuizaka, A Long, A Guo, ... Oncogene 34 (41), 5229-5239, 2015 | 88 | 2015 |
| Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities S Kagawa, M Natsuizaka, KA Whelan, N Facompre, S Naganuma, ... Oncogene 34 (18), 2347-2359, 2015 | 74 | 2015 |
| Human amnion-derived mesenchymal stem cell transplantation ameliorates dextran sulfate sodium-induced severe colitis in rats R Onishi, S Ohnishi, R Higashi, M Watari, K Yamahara, N Okubo, ... Cell transplantation 24 (12), 2601-2614, 2015 | 61 | 2015 |
| EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition F Sato, Y Kubota, M Natsuizaka, O Maehara, Y Hatanaka, K Marukawa, ... Cancer Biology & Therapy 16 (6), 933-940, 2015 | 60 | 2015 |
| Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4 ME Vega, V Giroux, M Natsuizaka, M Liu, AJ Klein-Szanto, DB Stairs, ... Cell Cycle 13 (24), 3857-3866, 2014 | 59 | 2014 |
Andres Klein-SzantoProfessor Emeritus, Fox Chase Cancer CenterDirección de correo verificada de fccc.edu
