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Hiroshi Nakagawa
Hiroshi Nakagawa
Research Associate Professor of Medicine, University of Pennsylvania
Dirección de correo verificada de mail.med.upenn.edu
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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
J Bartkova, N Rezaei, M Liontos, P Karakaidos, D Kletsas, N Issaeva, ...
Nature 444 (7119), 633-637, 2006
22822006
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
AJ Bass, H Watanabe, CH Mermel, S Yu, S Perner, RG Verhaak, SY Kim, ...
Nature genetics 41 (11), 1238-1242, 2009
10572009
Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo
CD Andl, T Mizushima, H Nakagawa, K Oyama, H Harada, K Chruma, ...
Journal of Biological Chemistry 278 (3), 1824-1830, 2003
3052003
Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation
J Okano, I Gaslightwala, MJ Birnbaum, AK Rustgi, H Nakagawa
Journal of Biological Chemistry 275 (40), 30934-30942, 2000
2692000
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
P Aggarwal, LP Vaites, JK Kim, H Mellert, B Gurung, H Nakagawa, ...
Cancer cell 18 (4), 329-340, 2010
2612010
Telomerase Induces Immortalization of Human Esophageal Keratinocytes Without p16INK4a Inactivation
H Harada, H Nakagawa, K Oyama, M Takaoka, CD Andl, B Jacobmeier, ...
Molecular Cancer Research 1 (10), 729-738, 2003
2332003
Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion
KD Grugan, CG Miller, Y Yao, CZ Michaylira, S Ohashi, AJ Klein-Szanto, ...
Proceedings of the National Academy of Sciences 107 (24), 11026-11031, 2010
2222010
Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells
K Liu, M Jiang, Y Lu, H Chen, J Sun, S Wu, WY Ku, H Nakagawa, Y Kita, ...
Cell stem cell 12 (3), 304-315, 2013
2002013
Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture
J Kalabis, GS Wong, ME Vega, M Natsuizaka, ES Robertson, M Herlyn, ...
Nature protocols 7 (2), 235-246, 2012
1822012
EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes
CD Andl, T Mizushima, K Oyama, M Bowser, H Nakagawa, AK Rustgi
American Journal of Physiology-Gastrointestinal and Liver Physiology 287 (6 …, 2004
1782004
The targeting of the cyclin D1 oncogene by an Epstein-Barr virus promoter in transgenic mice causes dysplasia in the tongue, esophagus and forestomach
H Nakagawa, TC Wang, L Zukerberg, R Odze, K Togawa, GHW May, ...
Oncogene 14 (10), 1185-1190, 1997
1711997
Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors
S Ohashi, M Natsuizaka, GS Wong, CZ Michaylira, KD Grugan, DB Stairs, ...
Cancer research 70 (10), 4174-4184, 2010
1702010
PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers
Y Li, N Chitnis, H Nakagawa, Y Kita, S Natsugoe, Y Yang, Z Li, M Wasik, ...
Cancer discovery 5 (3), 288-303, 2015
1642015
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification
J Kalabis, K Oyama, T Okawa, H Nakagawa, CZ Michaylira, DB Stairs, ...
The Journal of clinical investigation 118 (12), 3860-3869, 2008
1582008
Mutations in Fbx4 inhibit dimerization of the SCFFbx4 ligase and contribute to cyclin D1 overexpression in human cancer
O Barbash, P Zamfirova, DI Lin, X Chen, K Yang, H Nakagawa, F Lu, ...
Cancer cell 14 (1), 68-78, 2008
1552008
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network
S Ohashi, M Natsuizaka, Y Yashiro–Ohtani, RA Kalman, M Nakagawa, ...
Gastroenterology 139 (6), 2113-2123, 2010
1462010
The essential role of fibroblasts in esophageal squamous cell carcinoma–induced angiogenesis
K Noma, KSM Smalley, M Lioni, Y Naomoto, N Tanaka, W El–Deiry, ...
Gastroenterology 134 (7), 1981-1993, 2008
1462008
Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis
JJ Lee, M Natsuizaka, S Ohashi, GS Wong, M Takaoka, CZ Michaylira, ...
Carcinogenesis 31 (3), 427-434, 2010
1422010
A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors
S Ohashi, M Natsuizaka, S Naganuma, S Kagawa, S Kimura, H Itoh, ...
Cancer research 71 (21), 6836-6847, 2011
1302011
Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer
CZ Michaylira, GS Wong, CG Miller, CM Gutierrez, H Nakagawa, ...
Cancer research 70 (13), 5281-5292, 2010
1282010
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20