| Enhancement of proteasome activity by a small-molecule inhibitor of USP14 BH Lee, MJ Lee, S Park, DC Oh, S Elsasser, PC Chen, C Gartner, ... Nature 467 (7312), 179-184, 2010 | 1056 | 2010 |
| Deep multilayer brain proteomics identifies molecular networks in Alzheimer’s disease progression B Bai, X Wang, Y Li, PC Chen, K Yu, KK Dey, JM Yarbro, X Han, BM Lutz, ... Neuron 105 (6), 975-991. e7, 2020 | 435 | 2020 |
| U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, ... Proceedings of the National Academy of Sciences 110 (41), 16562-16567, 2013 | 318 | 2013 |
| Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3, 3 ‘-digallate,(−)-epigallocatechin-3-gallate, and propyl … JK Lin, PC Chen, CT Ho, SY Lin-Shiau Journal of Agricultural and Food Chemistry 48 (7), 2736-2743, 2000 | 254 | 2000 |
| Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discovery B Bai, D Vanderwall, Y Li, X Wang, S Poudel, H Wang, KK Dey, PC Chen, ... Molecular neurodegeneration 16 (1), 55, 2021 | 157 | 2021 |
| Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease H Wang, KK Dey, PC Chen, Y Li, M Niu, JH Cho, X Wang, B Bai, Y Jiao, ... Molecular neurodegeneration 15, 1-20, 2020 | 151 | 2020 |
| The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions PC Chen, LN Qin, XM Li, BJ Walters, JA Wilson, L Mei, SM Wilson Journal of Neuroscience 29 (35), 10909-10919, 2009 | 141 | 2009 |
| Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease KK Dey, H Wang, M Niu, B Bai, X Wang, Y Li, JH Cho, H Tan, A Mishra, ... Clinical proteomics 16, 1-12, 2019 | 123 | 2019 |
| Ubiquitin homeostasis is critical for synaptic development and function PC Chen, BJ Bhattacharyya, J Hanna, H Minkel, JA Wilson, D Finley, ... Journal of Neuroscience 31 (48), 17505-17513, 2011 | 110 | 2011 |
| Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity BJ Walters, SL Campbell, PC Chen, AP Taylor, DG Schroeder, ... Molecular and Cellular Neuroscience 39 (4), 539-548, 2008 | 87 | 2008 |
| Neuronal ubiquitin homeostasis J Hallengren, PC Chen, SM Wilson Cell biochemistry and biophysics 67, 67-73, 2013 | 79 | 2013 |
| CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer’s disease pathology W Su, J Saravia, I Risch, S Rankin, C Guy, NM Chapman, H Shi, Y Sun, ... Nature immunology 24 (10), 1735-1747, 2023 | 65 | 2023 |
| Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. JH Vaden, BJ Bhattacharyya, PC Chen, JA Watson, AG Marshall, ... Molecular Neurodegeneration 10 (3), doi:10.1186/1750-1326-10-3, 2015 | 54 | 2015 |
| Hypotriglyceridemic effect of Anka (a fermented rice product of Monascus sp.) in rats IK Wang, SY Lin-Shiau, PC Chen, JK Lin Journal of agricultural and food chemistry 48 (8), 3183-3189, 2000 | 52 | 2000 |
| Sequential elution interactome analysis of the mind bomb 1 ubiquitin ligase reveals a novel role in dendritic spine outgrowth J Mertz, H Tan, V Pagala, B Bai, PC Chen, Y Li, JH Cho, T Shaw, X Wang, ... Molecular & Cellular Proteomics 14 (7), 1898-1910, 2015 | 48 | 2015 |
| Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy NM Badders, A Korff, HC Miranda, PK Vuppala, RB Smith, BJ Winborn, ... Nature medicine 24 (4), 427-437, 2018 | 45 | 2018 |
| Transgenic rescue of ataxia mice reveals a male-specific sterility defect S Crimmins, M Sutovsky, PC Chen, A Huffman, C Wheeler, DA Swing, ... Developmental biology 325 (1), 33-42, 2009 | 45 | 2009 |
| Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits YN Jin, PC Chen, JA Watson, BJ Walters, SE Phillips, K Green, R Schmidt, ... PloS one 7 (10), e47884, 2012 | 38 | 2012 |
| Integrated approaches for analyzing U1-70K cleavage in Alzheimer’s disease B Bai, PC Chen, CM Hales, Z Wu, V Pagala, AA High, AI Levey, JJ Lah, ... Journal of proteome research 13 (11), 4526-4534, 2014 | 34 | 2014 |
| Alzheimer’s disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment PC Chen, X Han, TI Shaw, Y Fu, H Sun, M Niu, Z Wang, Y Jiao, ... Nature Aging, 923-940, 2022 | 27 | 2022 |
Junmin Peng, Ph.D.St. Jude Children's Research HospitalVerified email at stjude.org
