| The role of lactic acid production by probiotic Lactobacillus species in vaginal health G Tachedjian, M Aldunate, CS Bradshaw, RA Cone Research in microbiology 168 (9-10), 782-792, 2017 | 462 | 2017 |
| Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis M Aldunate, D Srbinovski, AC Hearps, CF Latham, PA Ramsland, ... Frontiers in physiology 6, 164, 2015 | 370 | 2015 |
| Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats P Zhou, M Tachedjian, JW Wynne, V Boyd, J Cui, I Smith, C Cowled, ... Proceedings of the National Academy of Sciences 113 (10), 2696-2701, 2016 | 329 | 2016 |
| Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors N Sluis-Cremer, G Tachedjian Virus research 134 (1-2), 147-156, 2008 | 240 | 2008 |
| The evolving facets of bacterial vaginosis: implications for HIV transmission LR McKinnon, SL Achilles, CS Bradshaw, A Burgener, T Crucitti, ... AIDS research and human retroviruses 35 (3), 219-228, 2019 | 217 | 2019 |
| Vaginal concentrations of lactic acid potently inactivate HIV M Aldunate, D Tyssen, A Johnson, T Zakir, S Sonza, T Moench, R Cone, ... Journal of Antimicrobial Chemotherapy 68 (9), 2015-2025, 2013 | 209 | 2013 |
| N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance SH Yap, CW Sheen, J Fahey, M Zanin, D Tyssen, VD Lima, B Wynhoven, ... PLoS Medicine 4 (12), e335, 2007 | 207 | 2007 |
| SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans CF Price, D Tyssen, S Sonza, A Davie, S Evans, GR Lewis, S Xia, ... PLoS One 6 (9), e24095, 2011 | 194 | 2011 |
| Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV … AC Hearps, D Tyssen, D Srbinovski, L Bayigga, DJD Diaz, M Aldunate, ... Mucosal immunology 10 (6), 1480-1490, 2017 | 193 | 2017 |
| Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities ST Henriques, YH Huang, KJ Rosengren, HG Franquelim, FA Carvalho, ... Journal of Biological Chemistry 286 (27), 24231-24241, 2011 | 188 | 2011 |
| The packaging and maturation of the HIV-1 Pol proteins M Hill, G Tachedjian, J Mak Current HIV research 3 (1), 73-85, 2005 | 186 | 2005 |
| Structure activity relationship of dendrimer microbicides with dual action antiviral activity D Tyssen, SA Henderson, A Johnson, J Sterjovski, K Moore, J La, M Zanin, ... PloS one 5 (8), e12309, 2010 | 182 | 2010 |
| Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions ST Henriques, YH Huang, MARB Castanho, LA Bagatolli, S Sonza, ... Journal of Biological Chemistry 287 (40), 33629-33643, 2012 | 140 | 2012 |
| An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3'-azido-3 … DJ Hooker, G Tachedjian, AE Solomon, AD Gurusinghe, S Land, C Birch, ... Journal of virology 70 (11), 8010-8018, 1996 | 140 | 1996 |
| Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase G Tachedjian, M Orlova, SG Sarafianos, E Arnold, SP Goff Proceedings of the National Academy of Sciences 98 (13), 7188-7193, 2001 | 135 | 2001 |
| Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol A Figueiredo, KL Moore, J Mak, N Sluis-Cremer, MP de Bethune, ... PLoS pathogens 2 (11), e119, 2006 | 126 | 2006 |
| Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1 S Telwatte, K Moore, A Johnson, D Tyssen, J Sterjovski, M Aldunate, ... Antiviral research 90 (3), 195-199, 2011 | 112 | 2011 |
| The implausible “in vivo” role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota G Tachedjian, DE O’Hanlon, J Ravel Microbiome 6, 1-5, 2018 | 110 | 2018 |
| Maturation of the HIV reverse transcription complex: putting the jigsaw together D Warrilow, G Tachedjian, D Harrich Reviews in medical virology 19 (6), 324-337, 2009 | 106 | 2009 |
| Distinct immune responses elicited from cervicovaginal epithelial cells by lactic acid and short chain fatty acids associated with optimal and non-optimal vaginal microbiota DJ Delgado-Diaz, D Tyssen, JA Hayward, R Gugasyan, AC Hearps, ... Frontiers in cellular and infection microbiology 9, 446, 2020 | 105 | 2020 |
