Joanne (Hulett) Hildebrand

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John SilkeProfessor, The Walter and Eliza Hall InstituteDirección de correo verificada de latrobe.edu.au
Andrew I. WebbAssociate Professor - The Walter and Eliza Hall InstituteDirección de correo verificada de wehi.edu.au
jeff babonwalter and eliza hall instituteDirección de correo verificada de wehi.edu.au
Najoua LalaouiGroup Leader, Peter MacCallum Cancer CenterDirección de correo verificada de petermac.org
Jian-Guo ZhangSenior Research Scientist, The Walter and Eliza Hall Institute of Medical Research, MelbourneDirección de correo verificada de wehi.edu.au
Renwick CJ DobsonProfessor of Chemical Biology, School of Biological Sciences, University of CanterburyDirección de correo verificada de canterbury.ac.nz
Paul GooleyUniversity of MelbourneDirección de correo verificada de unimelb.edu.au
Silvia Alvarez-DiazPostdoctoral Fellow at Walter and Eliza Hall Institute of Medical ResearchDirección de correo verificada de wehi.edu.au
Andreas StrasserThe Walter and Eliza Hall InstituteDirección de correo verificada de wehi.edu.au
Nicos A NicolaDivision Head, Walter and Eliza Hall InstituteDirección de correo verificada de wehi.edu.au
Andrew J. PerryDirección de correo verificada de monash.edu
Vladimir LikicDirección de correo verificada de spin.net.au
Martin ScanlonProfessor of Medicinal Chemistry, Monash UniversityDirección de correo verificada de monash.edu
Wei-Hao LinCarnegie Mellon UniversityDirección de correo verificada de cs.cmu.edu
Zhenghua LuoThe Ohio State UniversityDirección de correo verificada de osumc.edu
Ryan ListerUniversity of Western Australia; Harry Perkins Institute of Medical ResearchDirección de correo verificada de uwa.edu.au
Nicolas (Nic) TaylorAssociate Professor, The University of Western AustraliaDirección de correo verificada de uwa.edu.au
A. Harvey MillarARC Laureate Fellow | ARC Centre of Excellence in Plant Energy Biology, The University of WesternDirección de correo verificada de uwa.edu.au
Ross F WallerUniversity of CambridgeDirección de correo verificada de cam.ac.uk
Dr Pooja SharmaHarvard Medical School, Amgen, Monash University, WEHI-Melbourne University

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Joanne (Hulett) Hildebrand

Senior Research Scientist, WEHI

Dirección de correo verificada de wehi.edu.au - Página principal

Necroptosis Cell death MLKL


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013	1174	2013
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014	574	2014
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ... Nature communications 11 (1), 3151, 2020	234	2020
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ... Nature communications 9 (1), 2422, 2018	181	2018
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation JS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ... Nature microbiology 2 (4), 1-10, 2017	179	2017
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death AV Jacobsen, KN Lowes, MC Tanzer, IS Lucet, JM Hildebrand, EJ Petrie, ... Cell death & disease 7 (1), e2051-e2051, 2016	159	2016
Convergent evolution of receptors for protein import into mitochondria AJ Perry, JM Hulett, VA Likić, T Lithgow, PR Gooley Current Biology 16 (3), 221-229, 2006	141	2006
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Nature communications 6 (1), 6442, 2015	125	2015
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling JM Hildebrand, Z Luo, MK Manske, T Price-Troska, SC Ziesmer, W Lin, ... Journal of Experimental Medicine 207 (12), 2569-2579, 2010	122	2010
The transmembrane segment of Tom20 is recognized by Mim1 for docking to the mitochondrial TOM complex JM Hulett, F Lueder, NC Chan, AJ Perry, P Wolynec, VA Likić, PR Gooley, ... Journal of molecular biology 376 (3), 694-704, 2008	118	2008
Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions JM Hildebrand, Z Yi, CM Buchta, J Poovassery, LL Stunz, GA Bishop Immunological reviews 244 (1), 55-74, 2011	116	2011
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL JM Murphy, IS Lucet, JM Hildebrand, MC Tanzer, SN Young, P Sharma, ... Biochemical Journal 457 (3), 369-377, 2014	112	2014
Evolutionary divergence of the necroptosis effector MLKL MC Tanzer, I Matti, JM Hildebrand, SN Young, A Wardak, A Tripaydonis, ... Cell Death & Differentiation 23 (7), 1185-1197, 2016	108	2016
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop MC Tanzer, A Tripaydonis, AI Webb, SN Young, LN Varghese, C Hall, ... Biochemical Journal 471 (2), 255-265, 2015	107	2015
Protein import into mitochondria: origins and functions today R Lister, JM Hulett, T Lithgow, J Whelan Molecular membrane biology 22 (1-2), 87-100, 2005	104	2005
Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted MD Stutz, S Ojaimi, C Allison, S Preston, P Arandjelovic, JM Hildebrand, ... Cell Death & Differentiation 25 (5), 951-965, 2018	79	2018
Insane in the membrane: a structural perspective of MLKL function in necroptosis EJ Petrie, JM Hildebrand, JM Murphy Immunology and cell biology 95 (2), 152-159, 2017	78	2017
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction JM Hildebrand, M Kauppi, IJ Majewski, Z Liu, AJ Cox, S Miyake, EJ Petrie, ... Nature communications 11 (1), 3150, 2020	73	2020
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs S Murai, Y Yamaguchi, Y Shirasaki, M Yamagishi, R Shindo, ... Nature communications 9 (1), 4457, 2018	71	2018
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies EJ Petrie, RW Birkinshaw, A Koide, E Denbaum, JM Hildebrand, ... Proceedings of the National Academy of Sciences 117 (15), 8468-8475, 2020	65	2020

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