Hubert Lam
Hubert Lam
Affini-T Therapeutics
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D-amino acids govern stationary phase cell wall remodeling in bacteria
H Lam, DC Oh, F Cava, CN Takacs, J Clardy, MA de Pedro, MK Waldor
Science 325 (5947), 1552-1555, 2009
Emerging knowledge of regulatory roles of d-amino acids in bacteria
F Cava, H Lam, MA De Pedro, MK Waldor
Cellular and Molecular Life Sciences 68, 817-831, 2011
Distinct pathways for modification of the bacterial cell wall by non‐canonical D‐amino acids
F Cava, MA De Pedro, H Lam, BM Davis, MK Waldor
The EMBO journal 30 (16), 3442-3453, 2011
The tubulin homologue FtsZ contributes to cell elongation by guiding cell wall precursor synthesis in Caulobacter crescentus
M Aaron, G Charbon, H Lam, H Schwarz, W Vollmer, C Jacobs‐Wagner
Molecular microbiology 64 (4), 938-952, 2007
A landmark protein essential for establishing and perpetuating the polarity of a bacterial cell
H Lam, WB Schofield, C Jacobs-Wagner
Cell 124 (5), 1011-1023, 2006
Cytokinesis monitoring during development: rapid pole-to-pole shuttling of a signaling protein by localized kinase and phosphatase in Caulobacter
JY Matroule, H Lam, DT Burnette, C Jacobs-Wagner
Cell 118 (5), 579-590, 2004
The asymmetric spatial distribution of bacterial signal transduction proteins coordinates cell cycle events
H Lam, JY Matroule, C Jacobs-Wagner
Developmental cell 5 (1), 149-159, 2003
Substrate specificity of an elongation‐specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae
T Dörr, F Cava, H Lam, BM Davis, MK Waldor
Molecular Microbiology 89 (5), 949-962, 2013
Differential Requirement for PBP1a and PBP1b in In Vivo and In Vitro Fitness of Vibrio cholerae
T Dörr, A Möll, MC Chao, F Cava, H Lam, BM Davis, MK Waldor
Infection and immunity 82 (5), 2115-2124, 2014
An empirical antigen selection method identifies neoantigens that either elicit broad antitumor T-cell responses or drive tumor growth
H Lam, LK McNeil, H Starobinets, VL DeVault, RB Cohen, P Twardowski, ...
Cancer discovery 11 (3), 696-713, 2021
A Novel Peptidoglycan Binding Protein Crucial for PBP1A-Mediated Cell Wall Biogenesis in Vibrio cholerae
T Dörr, H Lam, L Alvarez, F Cava, BM Davis, MK Waldor
PLoS genetics 10 (6), e1004433, 2014
Antibodies to PhnD inhibit staphylococcal biofilms
H Lam, A Kesselly, S Stegalkina, H Kleanthous, JA Yethon
Infection and immunity 82 (9), 3764-3774, 2014
Improving cancer immunotherapies through empirical neoantigen selection
C Nogueira, JK Kaufmann, H Lam, JB Flechtner
Trends in Cancer 4 (2), 97-100, 2018
Limitations of murine models for assessment of antibody-mediated therapies or vaccine candidates against Staphylococcus epidermidis bloodstream infection
LE Cole, J Zhang, A Kesselly, NG Anosova, H Lam, H Kleanthous, ...
Infection and Immunity 84 (4), 1143-1149, 2016
Asymmetric Reduction of (Z)-α, β-Dehydrotryptophanyl-containing Biological Peptides with Sulfur Functionality. Influence of Substrate on Stereoselectivity
A Hammadi, H Lam, M Gondry, A Ménez, R Genet
Tetrahedron 56 (26), 4473-4477, 2000
Inhibigens, personal neoantigens that drive suppressive T cell responses, abrogate protection of therapeutic anti-tumor vaccines
VL DeVault, H Starobinets, S Adhikari, S Singh, S Rinaldi, B Classon, ...
The Journal of Immunology 204 (1_Supplement), 91.15-91.15, 2020
Treatment methods
JB Flechtner, M Lossky-Elias, PM Carroll, H Lam, LK McNeil, WJ Broom
US Patent 10,859,566, 2020
Preclinical development of safe and effective T cell receptors specific for mutant KRAS G12V and G12D peptides
T Martinov, R Perret, S Mureli, C McCurdy, A Vazquez, J Lee, J Webb, ...
MOLECULAR THERAPY 30 (4), 55-55, 2022
The Association of Blood Glucose and Diabetes with Abdominal Aortic Aneurysm, Carotid Stenosis and Peripheral Arterial Disease: An Observational Study of 630,000 Patients …
D Morris, R Bulbulia, P Sherliker, R Clack, H Lam, J Carter, A Halliday, ...
European Journal of Vascular and Endovascular Surgery 58 (6), e155, 2019
Vaccine neoantigens empirically identified through the ex vivo ATLAS platform promote potent therapeutic responses to cancer in mice
VL DeVault, H Starobinets, S Adhikari, S Rinaldi, SA Singh, A Li, ...
SITC https://sitc. planion. com/Web. User/AbstractDet, 2019
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