Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity J Antony, K Kellershohn, M Mohr‐Andrä, A Kebig, S Prilla, M Muth, ... The FASEB Journal 23 (2), 442-450, 2009 | 179 | 2009 |
Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors T Disingrini, M Muth, C Dallanoce, E Barocelli, S Bertoni, K Kellershohn, ... Journal of medicinal chemistry 49 (1), 366-372, 2006 | 92 | 2006 |
Synthesis and SAR of new pyrazolo [4, 3-h] quinazoline-3-carboxamide derivatives as potent and selective MPS1 kinase inhibitors M Caldarelli, M Angiolini, T Disingrini, D Donati, M Guanci, S Nuvoloni, ... Bioorganic & medicinal chemistry letters 21 (15), 4507-4511, 2011 | 60 | 2011 |
The generation of purinome-targeted libraries as a means to diversify ATP-mimetic chemical classes for lead finding ER Felder, A Badari, T Disingrini, S Mantegani, C Orrenius, N Avanzi, ... Molecular diversity 16, 27-51, 2012 | 20 | 2012 |
Regioselective halogenation of aminopyrimidinyl-pyrrole carboxylic acid derivatives E Vanotti, M Caldarelli, T Disingrini, M Nesi, M Tatò, P Vianello, ... Tetrahedron 65 (50), 10418-10423, 2009 | 6 | 2009 |
Stereoselective synthesis of 3, 4‐dihydropyrrolo [1, 2‐a] pyrazin‐1 (2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids F Casuscelli, E Ardini, N Avanzi, A Badari, E Casale, T Disingrini, ... Chirality 34 (11), 1437-1452, 2022 | 4 | 2022 |
Pyrazolyl-pyrimidine derivatives as kinase inhibitors F Casuscelli, MG Brasca, M Caldarelli, G Cervi, T Disingrini, F Quartieri US Patent 9,284,298, 2016 | 3 | 2016 |
Pyrazolo-quinazolines M Caldarelli, M Angiolini, R Colombo, T Disingrini, S Nuvolini, H Posteri, ... Patent WO 2009156315, A1, 0 | 3 | |
Tricyclopyrazole derivatives T Disingrini, S Mantegani, M Varasi US Patent 9,127,015, 2015 | 1 | 2015 |
Heterocondensed pyridones compounds and their use as IDH inhibitors E Casale, F Casuscelli, T Disingrini, P Magnaghi, B Malgesini, I Motto, ... US Patent 12,018,023, 2024 | | 2024 |
Gem-disubstituted heterocyclic compounds and their use as idh inhibitors F Casuscelli, T Disingrini, P Magnaghi, S Nuvoloni, P Orsini US Patent App. 17/775,124, 2023 | | 2023 |
Substituted 3, 4-dihydropyrrolo [1, 2-a] pyrazin-1 (2H)-ones as protein kinase inhibitors F Casuscelli, A Badari, SC Orrenius, C Piutti, T Disingrini US Patent 9,181,258, 2015 | | 2015 |
Allosteric Modulation of Muscarinic Acetylcholine-Receptors: Oxotremorine-Phthalimidoalkyl-Hybrids of the Hexamethonio-type T Disingrini, M Muth, E Barocelli, S Bertoni, M Deamici, C Demicheli, ... Atti Congresso, 2003 | | 2003 |
NMS-P715: DIFFERENT SYNTHETIC APPROACHES TOWARDS THE SYNTHESIS OF A POTENT AND SELECTIVE MPS1 KINASE INHIBITOR M Caldarelli, M Angiolini, T Disingrini, D Donati, M Guanci, S Nuvoloni, ... Nuove Prospettive in Chimica Farmaceutica, 59, 0 | | |