Prevention of transthyretin amyloid disease by changing protein misfolding energetics P Hammarstrom, RL Wiseman, ET Powers, JW Kelly Science 299 (5607), 713-716, 2003 | 613 | 2003 |
The biological and chemical basis for tissue-selective amyloid disease Y Sekijima, RL Wiseman, J Matteson, P Hammarström, SR Miller, ... Cell 121 (1), 73-85, 2005 | 537 | 2005 |
Sequence-dependent denaturation energetics: a major determinant in amyloid disease diversity P Hammarström, X Jiang, AR Hurshman, ET Powers, JW Kelly Proceedings of the National Academy of Sciences 99 (suppl_4), 16427-16432, 2002 | 425 | 2002 |
Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy M Lindgren, K Sörgjerd, P Hammarström Biophysical journal 88 (6), 4200-4212, 2005 | 398 | 2005 |
Novel Pentameric Thiophene Derivatives for in Vitro and in Vivo Optical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses A Åslund, CJ Sigurdson, T Klingstedt, S Grathwohl, T Bolmont, ... ACS chemical biology 4 (8), 673-684, 2009 | 376 | 2009 |
Trans-Suppression of Misfolding in an Amyloid Disease P Hammarström, F Schneider, JW Kelly Science 293 (5539), 2459-2462, 2001 | 345 | 2001 |
Prion strain discrimination using luminescent conjugated polymers CJ Sigurdson, KPR Nilsson, S Hornemann, G Manco, M Polymenidou, ... Nature methods 4 (12), 1023-1030, 2007 | 322 | 2007 |
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation C Maas, JWP Govers-Riemslag, B Bouma, B Schiks, BPC Hazenberg, ... The Journal of clinical investigation 118 (9), 3208-3218, 2008 | 295 | 2008 |
An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured X Jiang, CS Smith, HM Petrassi, P Hammarström, JT White, ... Biochemistry 40 (38), 11442-11452, 2001 | 277 | 2001 |
Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation KPR Nilsson, A Herland, P Hammarström, O Inganäs Biochemistry 44 (10), 3718-3724, 2005 | 230 | 2005 |
Imaging distinct conformational states of amyloid-β fibrils in Alzheimer’s disease using novel luminescent probes KPR Nilsson, A Åslund, I Berg, S Nyström, P Konradsson, A Herland, ... ACS chemical biology 2 (8), 553-560, 2007 | 224 | 2007 |
Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates T Klingstedt, A Åslund, RA Simon, LBG Johansson, JJ Mason, S Nyström, ... Organic & biomolecular chemistry 9 (24), 8356-8370, 2011 | 223 | 2011 |
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease J Rasmussen, J Mahler, N Beschorner, SA Kaeser, LM Häsler, ... Proceedings of the National Academy of Sciences 114 (49), 13018-13023, 2017 | 221 | 2017 |
Lysozyme amyloidogenesis is accelerated by specific nicking and fragmentation but decelerated by intact protein binding and conversion R Mishra, K Sörgjerd, S Nyström, A Nordigården, YC Yu, P Hammarström Journal of molecular biology 366 (3), 1029-1044, 2007 | 211 | 2007 |
Synthesis of a regioregular zwitterionic conjugated oligoelectrolyte, usable as an optical probe for detection of amyloid fibril formation at acidic pH A Herland, KPR Nilsson, JDM Olsson, P Hammarström, P Konradsson, ... Journal of the American Chemical Society 127 (7), 2317-2323, 2005 | 182 | 2005 |
Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila I Caesar, M Jonson, KPR Nilsson, S Thor, P Hammarström PloS one 7 (2), e31424, 2012 | 176 | 2012 |
D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis? P Hammarström, Y Sekijima, JT White, RL Wiseman, A Lim, CE Costello, ... Biochemistry 42 (22), 6656-6663, 2003 | 164 | 2003 |
Seeded strain‐like transmission of β‐amyloid morphotypes in APP transgenic mice G Heilbronner, YS Eisele, F Langer, SA Kaeser, R Novotny, ... EMBO reports 14 (11), 1017-1022, 2013 | 163 | 2013 |
Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red R Mishra, D Sjölander, P Hammarström Molecular BioSystems 7 (4), 1232-1240, 2011 | 159 | 2011 |
Conjugated polyelectrolytes—conformation‐sensitive optical probes for staining and characterization of amyloid deposits KPR Nilsson, P Hammarström, F Ahlgren, A Herland, EA Schnell, ... ChemBioChem 7 (7), 1096-1104, 2006 | 158 | 2006 |