Per Hammarstrom
Per Hammarstrom
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Prevention of transthyretin amyloid disease by changing protein misfolding energetics
P Hammarstrom, RL Wiseman, ET Powers, JW Kelly
Science 299 (5607), 713-716, 2003
The biological and chemical basis for tissue-selective amyloid disease
Y Sekijima, RL Wiseman, J Matteson, P Hammarström, SR Miller, ...
Cell 121 (1), 73-85, 2005
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity
P Hammarström, X Jiang, AR Hurshman, ET Powers, JW Kelly
Proceedings of the National Academy of Sciences 99 (suppl_4), 16427-16432, 2002
Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy
M Lindgren, K Sörgjerd, P Hammarström
Biophysical journal 88 (6), 4200-4212, 2005
Novel Pentameric Thiophene Derivatives for in Vitro and in Vivo Optical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses
A Åslund, CJ Sigurdson, T Klingstedt, S Grathwohl, T Bolmont, ...
ACS chemical biology 4 (8), 673-684, 2009
Trans-Suppression of Misfolding in an Amyloid Disease
P Hammarström, F Schneider, JW Kelly
Science 293 (5539), 2459-2462, 2001
Prion strain discrimination using luminescent conjugated polymers
CJ Sigurdson, KPR Nilsson, S Hornemann, G Manco, M Polymenidou, ...
Nature methods 4 (12), 1023-1030, 2007
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation
C Maas, JWP Govers-Riemslag, B Bouma, B Schiks, BPC Hazenberg, ...
The Journal of clinical investigation 118 (9), 3208-3218, 2008
An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured
X Jiang, CS Smith, HM Petrassi, P Hammarström, JT White, ...
Biochemistry 40 (38), 11442-11452, 2001
Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation
KPR Nilsson, A Herland, P Hammarström, O Inganäs
Biochemistry 44 (10), 3718-3724, 2005
Imaging distinct conformational states of amyloid-β fibrils in Alzheimer’s disease using novel luminescent probes
KPR Nilsson, A Åslund, I Berg, S Nyström, P Konradsson, A Herland, ...
ACS chemical biology 2 (8), 553-560, 2007
Lysozyme amyloidogenesis is accelerated by specific nicking and fragmentation but decelerated by intact protein binding and conversion
R Mishra, K Sörgjerd, S Nyström, A Nordigården, YC Yu, P Hammarström
Journal of molecular biology 366 (3), 1029-1044, 2007
Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates
T Klingstedt, A Åslund, RA Simon, LBG Johansson, JJ Mason, S Nyström, ...
Organic & biomolecular chemistry 9 (24), 8356-8370, 2011
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
J Rasmussen, J Mahler, N Beschorner, SA Kaeser, LM Häsler, ...
Proceedings of the National Academy of Sciences 114 (49), 13018-13023, 2017
Synthesis of a regioregular zwitterionic conjugated oligoelectrolyte, usable as an optical probe for detection of amyloid fibril formation at acidic pH
A Herland, KPR Nilsson, JDM Olsson, P Hammarström, P Konradsson, ...
Journal of the American Chemical Society 127 (7), 2317-2323, 2005
Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila
I Caesar, M Jonson, KPR Nilsson, S Thor, P Hammarström
PloS one 7 (2), e31424, 2012
Conjugated polyelectrolytes—conformation‐sensitive optical probes for staining and characterization of amyloid deposits
KPR Nilsson, P Hammarström, F Ahlgren, A Herland, EA Schnell, ...
ChemBioChem 7 (7), 1096-1104, 2006
D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?
P Hammarström, Y Sekijima, JT White, RL Wiseman, A Lim, CE Costello, ...
Biochemistry 42 (22), 6656-6663, 2003
Seeded strain‐like transmission of β‐amyloid morphotypes in APP transgenic mice
G Heilbronner, YS Eisele, F Langer, SA Kaeser, R Novotny, ...
EMBO reports 14 (11), 1017-1022, 2013
Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red
R Mishra, D Sjölander, P Hammarström
Molecular BioSystems 7 (4), 1232-1240, 2011
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Artículos 1–20