Deep multilayer brain proteomics identifies molecular networks in Alzheimer’s disease progression B Bai, X Wang, Y Li, PC Chen, K Yu, KK Dey, JM Yarbro, X Han, BM Lutz, ... Neuron 105 (6), 975-991. e7, 2020 | 310 | 2020 |
Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia ML Churchman, J Low, C Qu, EM Paietta, LH Kasper, Y Chang, ... Cancer cell 28 (3), 343-356, 2015 | 178 | 2015 |
Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation KP Bencsath, MS Podgorski, VR Pagala, CA Slaughter, BA Schulman Journal of Biological Chemistry 277 (49), 47938-47945, 2002 | 156 | 2002 |
Exercise protects against MPTP-induced neurotoxicity in mice KM Gerecke, Y Jiao, A Pani, V Pagala, RJ Smeyne Brain research 1341, 72-83, 2010 | 123 | 2010 |
CENP-A K124 ubiquitylation is required for CENP-A deposition at the centromere Y Niikura, R Kitagawa, H Ogi, R Abdulle, V Pagala, K Kitagawa Developmental cell 32 (5), 589-603, 2015 | 107 | 2015 |
Deep profiling of proteome and phosphoproteome by isobaric labeling, extensive liquid chromatography, and mass spectrometry B Bai, H Tan, VR Pagala, AA High, VP Ichhaporia, L Hendershot, J Peng Methods in enzymology 585, 377-395, 2017 | 94 | 2017 |
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase DC Scott, JT Hammill, J Min, DY Rhee, M Connelly, VO Sviderskiy, ... Nature chemical biology 13 (8), 850-857, 2017 | 83 | 2017 |
Proteomic studies of the intrinsically unstructured mammalian proteome CA Galea, VR Pagala, JC Obenauer, CG Park, CA Slaughter, ... Journal of proteome research 5 (10), 2839-2848, 2006 | 81 | 2006 |
Extensive Peptide Fractionation and y1 Ion-Based Interference Detection Method for Enabling Accurate Quantification by Isobaric Labeling and Mass Spectrometry M Niu, JH Cho, K Kodali, V Pagala, AA High, H Wang, Z Wu, Y Li, W Bi, ... Analytical chemistry 89 (5), 2956-2963, 2017 | 75 | 2017 |
Quantitative protein analysis by mass spectrometry VR Pagala, AA High, X Wang, H Tan, K Kodali, A Mishra, K Kavdia, Y Xu, ... Protein-Protein Interactions: Methods and Applications, 281-305, 2015 | 53 | 2015 |
Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes H Wang, AK Diaz, TI Shaw, Y Li, M Niu, JH Cho, BS Paugh, Y Zhang, ... Nature communications 10 (1), 3718, 2019 | 51 | 2019 |
A key role for the ubiquitin ligase UBR4 in myofiber hypertrophy in Drosophila and mice LC Hunt, J Stover, B Haugen, TI Shaw, Y Li, VR Pagala, D Finkelstein, ... Cell reports 28 (5), 1268-1281. e6, 2019 | 47 | 2019 |
Sequential elution interactome analysis of the mind bomb 1 ubiquitin ligase reveals a novel role in dendritic spine outgrowth J Mertz, H Tan, V Pagala, B Bai, PC Chen, Y Li, JH Cho, T Shaw, X Wang, ... Molecular & Cellular Proteomics 14 (7), 1898-1910, 2015 | 46 | 2015 |
Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1 X Yang, B Xu, B Mulvey, M Evans, S Jordan, YD Wang, V Pagala, J Peng, ... Nature neuroscience 22 (3), 362-373, 2019 | 35 | 2019 |
PAX7 is a required target for microRNA-206-induced differentiation of fusion-negative rhabdomyosarcoma JA Hanna, MR Garcia, JC Go, D Finkelstein, K Kodali, V Pagala, X Wang, ... Cell Death & Disease 7 (6), e2256-e2256, 2016 | 35 | 2016 |
Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophy LC Hunt, FA Graca, V Pagala, YD Wang, Y Li, ZF Yuan, Y Fan, M Labelle, ... Cell reports 37 (6), 2021 | 30 | 2021 |
Ybx1 fine-tunes PRC2 activities to control embryonic brain development MK Evans, Y Matsui, B Xu, C Willis, J Loome, L Milburn, Y Fan, V Pagala, ... Nature communications 11 (1), 4060, 2020 | 29 | 2020 |
Integrated approaches for analyzing U1-70K cleavage in Alzheimer’s disease B Bai, PC Chen, CM Hales, Z Wu, V Pagala, AA High, AI Levey, JJ Lah, ... Journal of proteome research 13 (11), 4526-4534, 2014 | 29 | 2014 |
T cell epitope" hotspots" on the HIV Type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry SA Brown, TD Lockey, C Slaughter, KS Slobod, S Surman, A Zirkel, ... AIDS Research & Human Retroviruses 21 (2), 165-170, 2005 | 29 | 2005 |
Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging LC Hunt, B Schadeberg, J Stover, B Haugen, V Pagala, YD Wang, ... Nature Communications 12 (1), 1418, 2021 | 27 | 2021 |