| Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress R Tao, MC Coleman, JD Pennington, O Ozden, SH Park, H Jiang, HS Kim, ... Molecular cell 40 (6), 893-904, 2010 | 1014 | 2010 |
| SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress HS Kim, K Patel, K Muldoon-Jacobs, KS Bisht, N Aykin-Burns, ... Cancer cell 17 (1), 41-52, 2010 | 927 | 2010 |
| SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity HS Kim, A Vassilopoulos, RH Wang, T Lahusen, Z Xiao, X Xu, C Li, ... Cancer cell 20 (4), 487-499, 2011 | 613 | 2011 |
| SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells O Ozden, SH Park, BA Wagner, HY Song, Y Zhu, A Vassilopoulos, B Jung, ... Free Radical Biology and Medicine 76, 163-172, 2014 | 201 | 2014 |
| Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress O Ozden, SH Park, HS Kim, H Jiang, MC Coleman, DR Spitz, D Gius Aging (Albany NY) 3 (2), 102, 2011 | 191 | 2011 |
| Loss of NAD-dependent protein deacetylase sirtuin-2 alters mitochondrial protein acetylation and dysregulates mitophagy G Liu, SH Park, M Imbesi, WJ Nathan, X Zou, Y Zhu, H Jiang, L Parisiadou, ... Antioxidants & redox signaling 26 (15), 849-863, 2017 | 136 | 2017 |
| Sirt3, mitochondrial ROS, ageing, and carcinogenesis SH Park, O Ozden, H Jiang, YI Cha, JD Pennington, N Aykin-Burns, ... International journal of molecular sciences 12 (9), 6226-6239, 2011 | 132 | 2011 |
| Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2 X Yang, SH Park, HC Chang, JS Shapiro, A Vassilopoulos, KT Sawicki, ... The Journal of clinical investigation 127 (4), 1505-1516, 2017 | 122 | 2017 |
| SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth SH Park, O Ozden, G Liu, HY Song, Y Zhu, Y Yan, X Zou, HJ Kang, ... Cancer research 76 (13), 3802-3812, 2016 | 121 | 2016 |
| SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis SH Park, Y Zhu, O Ozden, HS Kim, H Jiang, CX Deng, D Gius, ... Translational cancer research 1 (1), 15, 2012 | 115 | 2012 |
| SIRT2 directs the replication stress response through CDK9 deacetylation H Zhang, SH Park, BG Pantazides, O Karpiuk, MD Warren, CW Hardy, ... Proceedings of the National Academy of Sciences 110 (33), 13546-13551, 2013 | 107 | 2013 |
| SIRT3-mediated dimerization of IDH2 directs cancer cell metabolism and tumor growth X Zou, Y Zhu, SH Park, G Liu, J O'Brien, H Jiang, D Gius Cancer research 77 (15), 3990-3999, 2017 | 77 | 2017 |
| ATRIP deacetylation by SIRT2 drives ATR checkpoint activation by promoting binding to RPA-ssDNA H Zhang, PSE Head, W Daddacha, SH Park, X Li, Y Pan, MZ Madden, ... Cell reports 14 (6), 1435-1447, 2016 | 74 | 2016 |
| Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity Y Zhu, SH Park, O Ozden, HS Kim, H Jiang, A Vassilopoulos, DR Spitz, ... Free Radical Biology and Medicine 53 (4), 828-833, 2012 | 70 | 2012 |
| SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a MJ Kim, K Ahn, SH Park, HJ Kang, BG Jang, SJ Oh, SM Oh, YJ Jeong, ... FEBS letters 583 (7), 1183-1188, 2009 | 69 | 2009 |
| Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter Nature Communications 10 (1), 2399, 2019 | 48 | 2019 |
| Neuronal loss in primary long-term cortical culture involves neurodegeneration-like cell death via calpain and p35 processing, but not developmental apoptosis or aging MJ Kim, SJ Oh, SH Park, HJ Kang, MH Won, TC Kang, JB Park, JI Kim, ... Experimental & molecular medicine 39 (1), 14-26, 2007 | 40 | 2007 |
| SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status HY Song, M Biancucci, HJ Kang, C O'Callaghan, SH Park, DR Principe, ... Oncotarget 7 (49), 80336, 2016 | 37 | 2016 |
| Effect of combined treatment with progesterone and tamoxifen on the growth and apoptosis of human ovarian cancer cells JY Lee, JY Shin, HS Kim, JI Heo, YJ Kho, HJ Kang, SH Park, JY Lee Oncology reports 27 (1), 87-93, 2012 | 33 | 2012 |
| Calorie restriction (CR) reduces age-dependent decline of non-homologous end joining (NHEJ) activity in rat tissues JE Lee, JI Heo, SH Park, JH Kim, YJ Kho, HJ Kang, HY Chung, JL Yoon, ... Experimental gerontology 46 (11), 891-896, 2011 | 31 | 2011 |
David GiusUniversity of Texas Health Sciences Center San AntonioDirección de correo verificada de northwestern.edu
