Jeremy Chien
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Integrated genomic analyses of ovarian carcinoma
Cancer Genome Atlas Research Network
Nature 474 (7353), 609, 2011
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
Z Yang, NJ Camp, H Sun, Z Tong, D Gibbs, DJ Cameron, H Chen, Y Zhao, ...
Science 314 (5801), 992-993, 2006
Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer
J Lai, J Chien, J Staub, R Avula, EL Greene, TA Matthews, DI Smith, ...
Journal of Biological Chemistry 278 (25), 23107-23117, 2003
Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice
Z Yang, Y Chen, C Lillo, J Chien, Z Yu, M Michaelides, M Klein, ...
The Journal of clinical investigation 118 (8), 2908-2916, 2008
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer
J Chien, J Staub, SI Hu, MR Erickson-Johnson, FJ Couch, DI Smith, ...
Oncogene 23 (8), 1636-1644, 2004
Metformin intake is associated with better survival in ovarian cancer: A case‐control study
S Kumar, A Meuter, P Thapa, C Langstraat, S Giri, J Chien, R Rattan, ...
Cancer 119 (3), 555-562, 2013
Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity
J Chien, G Aletti, A Baldi, V Catalano, P Muretto, GL Keeney, KR Kalli, ...
The Journal of clinical investigation 116 (7), 1994-2004, 2006
hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling
J Lai, JR Chien, DR Moser, JK Staub, I Aderca, DP Montoya, TA Matthews, ...
Gastroenterology 126 (1), 231-248, 2004
APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma
B Leonard, SN Hart, MB Burns, MA Carpenter, NA Temiz, A Rathore, ...
Cancer research 73 (24), 7222-7231, 2013
HSulf-1 inhibits angiogenesis and tumorigenesis in vivo
K Narita, J Staub, J Chien, K Meyer, M Bauer, A Friedl, S Ramakrishnan, ...
Cancer research 66 (12), 6025-6032, 2006
Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment
W Zhang, T Ota, V Shridhar, J Chien, B Wu, R Kuang
PLoS computational biology 9 (3), e1002975, 2013
HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma
JP Lai, J Chien, SE Strome, J Staub, DP Montoya, EL Greene, DI Smith, ...
Oncogene 23 (7), 1439-1447, 2004
Clinical Characteristics of Ovarian Cancer Classified by BRCA1, BRCA2 and RAD51C Status
JM Cunningham, MS Cicek, NB Larson, J Davila, C Wang, MC Larson, ...
Scientific reports 4 (1), 4026, 2014
HtrA serine proteases as potential therapeutic targets in cancer
J Chien, M Campioni, V Shridhar, A Baldi
Current cancer drug targets 9 (4), 451-468, 2009
Serine protease HtrA1 associates with microtubules and inhibits cell migration
J Chien, T Ota, G Aletti, R Shridhar, M Boccellino, L Quagliuolo, A Baldi, ...
Molecular and cellular biology 29 (15), 4177-4187, 2009
Epigenetic silencing of HSulf-1 in ovarian cancer: implications in chemoresistance
J Staub, J Chien, Y Pan, X Qian, K Narita, G Aletti, M Scheerer, ...
Oncogene 26 (34), 4969-4978, 2007
Identification of underexpressed genes in early-and late-stage primary ovarian tumors by suppression subtraction hybridization
V Shridhar, A Sen, J Chien, J Staub, R Avula, S Kovats, J Lee, J Lillie, ...
Cancer research 62 (1), 262-270, 2002
Bevacizumab may differentially improve ovarian cancer outcome in patients with proliferative and mesenchymal molecular subtypes
S Kommoss, B Winterhoff, AL Oberg, GE Konecny, C Wang, SM Riska, ...
Clinical Cancer Research 23 (14), 3794-3801, 2017
Platinum-sensitive recurrence in ovarian cancer: the role of tumor microenvironment
J Chien, R Kuang, C Landen, V Shridhar
Frontiers in oncology 3, 251, 2013
FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq
Y Li, J Chien, DI Smith, J Ma
Bioinformatics 27 (12), 1708-1710, 2011
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