The molecular relationships between apoptosis, autophagy and necroptosis N Lalaoui, LM Lindqvist, JJ Sandow, PG Ekert Seminars in cell & developmental biology 39, 63-69, 2015 | 223 | 2015 |
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ... Nature communications 9 (1), 2422, 2018 | 186 | 2018 |
VDAC2 enables BAX to mediate apoptosis and limit tumor development H San Chin, MX Li, IKL Tan, RL Ninnis, B Reljic, K Scicluna, LF Dagley, ... Nature Communications 9 (1), 4976, 2018 | 148 | 2018 |
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ... Cell 184 (12), 3143-3162. e32, 2021 | 138 | 2021 |
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Nature communications 6, 6442, 2015 | 131 | 2015 |
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity Z Fan, JR Devlin, SJ Hogg, MA Doyle, PF Harrison, I Todorovski, ... Science Advances 6 (18), eaaz5041, 2020 | 120 | 2020 |
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1 J Le Nours, NA Gherardin, SH Ramarathinam, W Awad, F Wiede, ... Science 366 (6472), 1522-1527, 2019 | 119 | 2019 |
Signalling by the βc family of cytokines TR Hercus, U Dhagat, WLT Kan, SE Broughton, TL Nero, M Perugini, ... Cytokine & growth factor reviews 24 (3), 189-201, 2013 | 105 | 2013 |
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy JP Bernardini, JM Brouwer, IKL Tan, JJ Sandow, S Huang, CA Stafford, ... The EMBO journal 38 (2), e99916, 2019 | 95 | 2019 |
Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex W Wong, R Huang, S Menant, C Hong, JJ Sandow, RW Birkinshaw, ... Nature 565 (7737), 118-121, 2019 | 94 | 2019 |
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3 EJ Petrie, JJ Sandow, WIL Lehmann, LY Liang, D Coursier, SN Young, ... Cell Reports 28 (13), 3309-3319. e5, 2019 | 91 | 2019 |
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ... Molecular Cell 81 (10), 2183-2200. e13, 2021 | 86 | 2021 |
Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim AM Jabbour, JE Heraud, CP Daunt, T Kaufmann, J Sandow, LA O'Reilly, ... Cell Death & Differentiation 16 (4), 555-563, 2009 | 86 | 2009 |
The regulation of necroptosis by post-translational modifications Y Meng, JJ Sandow, PE Czabotar, JM Murphy Cell Death & Differentiation, 1-23, 0 | 81 | |
CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell MemoryInhibition of CDK4/6 Promotes T-Cell Memory EJ Lelliott, IY Kong, M Zethoven, KM Ramsbottom, LG Martelotto, ... Cancer Discovery 11 (10), 2582-2601, 2021 | 80 | 2021 |
Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted MD Stutz, S Ojaimi, C Allison, S Preston, P Arandjelovic, JM Hildebrand, ... Cell Death & Differentiation 25 (5), 951-965, 2018 | 80 | 2018 |
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte DS Marapana, LF Dagley, JJ Sandow, T Nebl, T Triglia, M Pasternak, ... Nature microbiology 3 (9), 1010-1022, 2018 | 69 | 2018 |
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis SE Garnish, Y Meng, A Koide, JJ Sandow, E Denbaum, AV Jacobsen, ... Nature Communications 12 (1), 1-14, 2021 | 68 | 2021 |
ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism (vol 71, pg 861, 2020) ST Boyle, V Poltavets, J Kular, NT Pyne, JJ Sandow, AC Lewis, ... NATURE CELL BIOLOGY 22 (7), 908-908, 2020 | 68 | 2020 |
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies EJ Petrie, RW Birkinshaw, A Koide, E Denbaum, JM Hildebrand, ... Proceedings of the National Academy of Sciences 117 (15), 8468-8475, 2020 | 67 | 2020 |