Andrzej Dziembowski
Andrzej Dziembowski
International Institute of Molecular and Cell Biology
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A single subunit, Dis3, is essentially responsible for yeast exosome core activity
A Dziembowski, E Lorentzen, E Conti, B Séraphin
Nature structural & molecular biology 14 (1), 15-22, 2007
Mitochondrial double-stranded RNA triggers antiviral signalling in humans
A Dhir, S Dhir, LS Borowski, L Jimenez, M Teitell, A Rötig, YJ Crow, ...
Nature 560 (7717), 238-242, 2018
PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures
PS Krawczyk, L Lipinski, A Dziembowski
Nucleic acids research 46 (6), e35-e35, 2018
Interaction profiling identifies the human nuclear exosome targeting complex
M Lubas, MS Christensen, MS Kristiansen, M Domanski, LG Falkenby, ...
Molecular cell 43 (4), 624-637, 2011
Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol
L Wrobel, U Topf, P Bragoszewski, S Wiese, ME Sztolsztener, ...
Nature 524 (7566), 485-488, 2015
Endonucleolytic RNA cleavage by a eukaryotic exosome
A Lebreton, R Tomecki, A Dziembowski, B Séraphin
Nature 456 (7224), 993-996, 2008
Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression
H Mathys, J Basquin, S Ozgur, M Czarnocki-Cieciura, F Bonneau, ...
Molecular cell 54 (5), 751-765, 2014
The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
R Tomecki, MS Kristiansen, S Lykke‐Andersen, A Chlebowski, KM Larsen, ...
The EMBO journal 29 (14), 2342-2357, 2010
RNA decay machines: the exosome
A Chlebowski, M Lubas, TH Jensen, A Dziembowski
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (6-7 …, 2013
Cytoplasmic RNA decay pathways-Enzymes and mechanisms
A Łabno, R Tomecki, A Dziembowski
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (12), 3125-3147, 2016
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family
E Lorentzen, J Basquin, R Tomecki, A Dziembowski, E Conti
Molecular cell 29 (6), 717-728, 2008
Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci
LS Borowski, A Dziembowski, MS Hejnowicz, PP Stepien, RJ Szczesny
Nucleic acids research 41 (2), 1223-1240, 2013
Identification of a novel human nuclear-encoded mitochondrial poly (A) polymerase
R Tomecki, A Dmochowska, K Gewartowski, A Dziembowski, PP Stepien
Nucleic acids research 32 (20), 6001-6014, 2004
Subunit architecture of multimeric complexes isolated directly from cells
H Hernández, A Dziembowski, T Taverner, B Séraphin, CV Robinson
EMBO reports 7 (6), 605-610, 2006
The human nuclear exosome targeting complex is loaded onto newly synthesized RNA to direct early ribonucleolysis
M Lubas, PR Andersen, A Schein, A Dziembowski, G Kudla, TH Jensen
Cell reports 10 (2), 178-192, 2015
Proteomic analysis identifies a new complex required for nuclear pre‐mRNA retention and splicing
A Dziembowski, AP Ventura, B Rutz, F Caspary, C Faux, F Halgand, ...
The EMBO journal 23 (24), 4847-4856, 2004
Exonuclease hDIS3L2 specifies an exosome‐independent 3′‐5′ degradation pathway of human cytoplasmic mRNA
M Lubas, CK Damgaard, R Tomecki, D Cysewski, TH Jensen, ...
The EMBO journal 32 (13), 1855-1868, 2013
The yeast mitochondrial degradosome: its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism
A Dziembowski, J Piwowarski, R Hoser, M Minczuk, A Dmochowska, ...
Journal of Biological Chemistry 278 (3), 1603-1611, 2003
The eukaryotic RNA exosome: same scaffold but variable catalytic subunits
S Lykke-Andersen, R Tomecki, TH Jensen, A Dziembowski
RNA biology 8 (1), 61-66, 2011
The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro
K Drążkowska, R Tomecki, K Stoduś, K Kowalska, M Czarnocki-Cieciura, ...
Nucleic acids research 41 (6), 3845-3858, 2013
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