| Positive allosteric modulation of cannabinoid receptor type 1 suppresses pathological pain without producing tolerance or dependence RA Slivicki, Z Xu, PM Kulkarni, RG Pertwee, K Mackie, GA Thakur, ... Biological psychiatry 84 (10), 722-733, 2018 | 127 | 2018 |
| Enantiospecific allosteric modulation of cannabinoid 1 receptor RB Laprairie, PM Kulkarni, JR Deschamps, MEM Kelly, DR Janero, ... ACS chemical neuroscience 8 (6), 1188-1203, 2017 | 98 | 2017 |
| Novel electrophilic and photoaffinity covalent probes for mapping the cannabinoid 1 receptor allosteric site (s) PM Kulkarni, AR Kulkarni, A Korde, RB Tichkule, RB Laprairie, ... Journal of medicinal chemistry 59 (1), 44-60, 2016 | 65 | 2016 |
| Small molecule inhibitors of PSD95-nNOS protein–protein interactions as novel analgesics WH Lee, Z Xu, NM Ashpole, A Hudmon, PM Kulkarni, GA Thakur, YY Lai, ... Neuropharmacology 97, 464-475, 2015 | 64 | 2015 |
| Application of fluorine-and nitrogen-walk approaches: defining the structural and functional diversity of 2-phenylindole class of cannabinoid 1 receptor positive allosteric … S Garai, PM Kulkarni, PC Schaffer, LM Leo, AL Brandt, A Zagzoog, ... Journal of medicinal chemistry 63 (2), 542-568, 2019 | 49 | 2019 |
| Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model RB Laprairie, AM Bagher, JL Rourke, A Zrein, EA Cairns, MEM Kelly, ... Neuropharmacology 151, 1-12, 2019 | 45 | 2019 |
| Mapping cannabinoid 1 receptor allosteric site (s): critical molecular determinant and signaling profile of GAT100, a novel, potent, and irreversibly binding probe RB Laprairie, AR Kulkarni, PM Kulkarni, DP Hurst, D Lynch, PH Reggio, ... ACS Chemical Neuroscience 7 (6), 776–798, 2016 | 37 | 2016 |
| Identification of CB1 receptor allosteric sites using force-biased MMC simulated annealing and validation by structure–activity relationship studies DP Hurst, S Garai, PM Kulkarni, PC Schaffer, PH Reggio, GA Thakur ACS medicinal chemistry letters 10 (8), 1216-1221, 2019 | 36 | 2019 |
| Allosteric cannabinoid receptor 1 (CB1) ligands reduce ocular pain and inflammation D Thapa, EA Cairns, AM Szczesniak, PM Kulkarni, AJ Straiker, GA Thakur, ... Molecules 25 (2), 417, 2020 | 34 | 2020 |
| Small molecule inhibitors of PSD95–nNOS protein–protein interactions suppress formalin-evoked Fos protein expression and nociceptive behavior in rats LM Carey, WH Lee, T Gutierrez, PM Kulkarni, GA Thakur, YY Lai, ... Neuroscience 349, 303-317, 2017 | 34 | 2017 |
| Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein–protein interaction inhibitors JDC Alexandra E. Smith, Zhili Xu, Yvonne Y. Lai, Pushkar M. Kulkarni, Ganesh ... Behavioural Brain Research 305, 23-29, 2016 | 31 | 2016 |
| Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons J Mitjavila, D Yin, PM Kulkarni, C Zanato, GA Thakur, R Ross, I Greig, ... Pharmacological research 129, 475-481, 2018 | 30 | 2018 |
| The In Vivo Effects of the CB1-Positive Allosteric Modulator GAT229 on Intraocular Pressure in Ocular Normotensive and Hypertensive Mice KMEM Cairns Elizabeth A., Szczesniak Anna-Maria, Straiker Alex J., Kulkarni ... Journal of Ocular Pharmacology and Therapeutics, 2017 | 26 | 2017 |
| Microwave‐accelerated conjugate addition of 2‐arylindoles to substituted β‐nitrostyrenes in the presence of ammonium trifluoroacetate: An efficient approach for the synthesis … PM Kulkarni, A Ranade, S Garai, GA Thakur Journal of Heterocyclic Chemistry 54 (3), 2079-2084, 2017 | 13 | 2017 |
| Allosteric modulators of CB1 cannabinoid receptors GA Thakur, PM Kulkarni US Patent 10,246,414, 2019 | 10 | 2019 |
| Allosteric modulators of the cannabinoid 1 receptor GA Thakur, RB Tichkule, PM Kulkarni, AR Kulkarni US Patent 9,926,275, 2018 | 9 | 2018 |
| Inhibition of PSD95‐nNOS protein–protein interactions decreases morphine reward and relapse vulnerability in rats I Oliva, SA Saberi, C Rangel‐Barajas, V Iyer, KD Bunner, YY Lai, ... Addiction Biology 27 (5), e13220, 2022 | 6 | 2022 |
| Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic … PC Schaffer, PM Kulkarni, DR Janero, GA Thakur Bioorganic & Medicinal Chemistry 28 (21), 115727, 2020 | 5 | 2020 |
| A high‐specificity aniline‐based mass tag for aldehyde detection P Mungalachetty, P Kulkarni, P Wang, R Giese Rapid Communications in Mass Spectrometry 36 (15), e9322, 2022 | 1 | 2022 |
| Sorptive Tab Device for Breath Collection and Analysis P Kulkarni, P Wang, RW Giese US Patent App. 15/897,602, 2018 | 1 | 2018 |
Ganesh ThakurNortheastern UniversityDirección de correo verificada de neu.edu
