Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis HS Leong, AE Robertson, K Stoletov, SJ Leith, CA Chin, AE Chien, ... Cell reports 8 (5), 1558-1570, 2014 | 438 | 2014 |
On the issue of transparency and reproducibility in nanomedicine HS Leong, KS Butler, CJ Brinker, M Azzawi, S Conlan, C Dufès, A Owen, ... Nature nanotechnology 14 (7), 629-635, 2019 | 180 | 2019 |
Intravital imaging of embryonic and tumor neovasculature using viral nanoparticles HS Leong, NF Steinmetz, A Ablack, G Destito, A Zijlstra, H Stuhlmann, ... Nature protocols 5 (8), 1406-1417, 2010 | 180 | 2010 |
Translational models of prostate cancer bone metastasis RB Berish, AN Ali, PG Telmer, JA Ronald, HS Leong Nature Reviews Urology 15 (7), 403-421, 2018 | 139 | 2018 |
The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk E Arpaia, H Blaser, M Quintela-Fandino, G Duncan, HS Leong, A Ablack, ... Oncogene 31 (7), 884-896, 2012 | 134 | 2012 |
Autoantibodies to vimentin cause accelerated rejection of cardiac allografts B Mahesh, HS Leong, A McCormack, P Sarathchandra, A Holder, ... The American journal of pathology 170 (4), 1415-1427, 2007 | 133 | 2007 |
Glycolysis and pyruvate oxidation in cardiac hypertrophy—why so unbalanced? HS Leong, RW Brownsey, JE Kulpa, MF Allard Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2003 | 118 | 2003 |
Structural and molecular mechanisms of cytokine-mediated endocrine resistance in human breast cancer cells JD Stender, JC Nwachukwu, I Kastrati, Y Kim, T Strid, M Yakir, ... Molecular cell 65 (6), 1122-1135. e5, 2017 | 117 | 2017 |
Re-examining the size/charge paradigm: differing in vivo characteristics of size-and charge-matched mesoporous silica nanoparticles JL Townson, YS Lin, JO Agola, EC Carnes, HS Leong, JD Lewis, ... Journal of the American Chemical Society 135 (43), 16030-16033, 2013 | 113 | 2013 |
Probiotic Lactobacillus rhamnosus reduces organophosphate pesticide absorption and toxicity to Drosophila melanogaster M Trinder, TW McDowell, BA Daisley, SN Ali, HS Leong, MW Sumarah, ... Applied and Environmental Microbiology 82 (20), 6204-6213, 2016 | 109 | 2016 |
Neonicotinoid-induced pathogen susceptibility is mitigated by Lactobacillus plantarum immune stimulation in a Drosophila melanogaster model BA Daisley, M Trinder, TW McDowell, H Welle, JS Dube, SN Ali, ... Scientific reports 7 (1), 2703, 2017 | 107 | 2017 |
Differential functional roles of ALDH1A1 and ALDH1A3 in mediating metastatic behavior and therapy resistance of human breast cancer cells AK Croker, M Rodriguez-Torres, Y Xia, S Pardhan, HS Leong, JD Lewis, ... International journal of molecular sciences 18 (10), 2039, 2017 | 99 | 2017 |
Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis A Mesci, X Huang, S Taeb, S Jahangiri, Y Kim, E Fokas, J Bruce, ... British journal of cancer 116 (10), 1350-1357, 2017 | 90 | 2017 |
Immunoaffinity based methods are superior to kits for purification of prostate derived extracellular vesicles from plasma samples SI Brett, F Lucien, C Guo, KC Williams, Y Kim, PN Durfee, CJ Brinker, ... The Prostate 77 (13), 1335-1343, 2017 | 87 | 2017 |
Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry CN Biggs, KM Siddiqui, AA Al-Zahrani, S Pardhan, SI Brett, QQ Guo, ... Oncotarget 7 (8), 8839, 2016 | 82 | 2016 |
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in coxsackievirus-induced myocarditis C Cheung, H Luo, B Yanagawa, HS Leong, D Samarasekera, JCK Lai, ... Cardiovascular Pathology 15 (2), 63-74, 2006 | 82 | 2006 |
The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase MJ Martin, N Melnyk, M Pollard, M Bowden, H Leong, TJ Podor, M Gleave, ... Molecular and cellular biology 26 (5), 1754-1769, 2006 | 79 | 2006 |
Quantification of cancer cell extravasation in vivo Y Kim, KC Williams, CT Gavin, E Jardine, AF Chambers, HS Leong Nature protocols 11 (5), 937-948, 2016 | 78 | 2016 |
Accelerated rates of glycolysis in the hypertrophied heart: are they a methodological artifact? HS Leong, M Grist, H Parsons, RB Wambolt, GD Lopaschuk, R Brownsey, ... American Journal of Physiology-Endocrinology and Metabolism 282 (5), E1039-E1045, 2002 | 74 | 2002 |
Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients FH Joncas, F Lucien, M Rouleau, F Morin, HS Leong, F Pouliot, Y Fradet, ... The Prostate 79 (15), 1767-1776, 2019 | 72 | 2019 |