| Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by β-amyloid peptides via p38 mitogen-activated protein kinase pathway PM Canas, LO Porciúncula, GMA Cunha, CG Silva, NJ Machado, ... Journal of Neuroscience 29 (47), 14741-14751, 2009 | 390 | 2009 |
| Neuroprotection by caffeine and adenosine A2A receptor blockade of β‐amyloid neurotoxicity OP Dall'lgna, LO Porciúncula, DO Souza, RA Cunha, DR Lara British journal of pharmacology 138 (7), 1207-1209, 2003 | 328 | 2003 |
| Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes RG Tavares, CI Tasca, CES Santos, LB Alves, LO Porciúncula, ... Neurochemistry international 40 (7), 621-627, 2002 | 317 | 2002 |
| Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress MP Kaster, NJ Machado, HB Silva, A Nunes, AP Ardais, M Santana, ... Proceedings of the National Academy of Sciences 112 (25), 7833-7838, 2015 | 303 | 2015 |
| Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A 2A receptors upregulation in the hippocampus of a rat model of sporadic dementia J Espinosa, A Rocha, F Nunes, MS Costa, V Schein, V Kazlauckas, ... Journal of Alzheimer's Disease 34 (2), 509-518, 2013 | 167 | 2013 |
| Caffeine prevents disruption of memory consolidation in the inhibitory avoidance and novel object recognition tasks by scopolamine in adult mice PH Botton, MS Costa, AP Ardais, S Mioranzza, DO Souza, JBT da Rocha, ... Behavioural brain research 214 (2), 254-259, 2010 | 146 | 2010 |
| Caffeine prevents age-associated recognition memory decline and changes brain-derived neurotrophic factor and tirosine kinase receptor (TrkB) content in mice MS Costa, PH Botton, S Mioranzza, DO Souza, LO Porciúncula Neuroscience 153 (4), 1071-1078, 2008 | 145 | 2008 |
| Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons LO Porciúncula, JBT Rocha, CR Boeck, D Vendite, DO Souza Neuroscience letters 299 (3), 217-220, 2001 | 133 | 2001 |
| Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus MS Costa, PH Botton, S Mioranzza, AP Ardais, JD Moreira, DO Souza, ... Neurochemistry international 53 (3-4), 89-94, 2008 | 124 | 2008 |
| Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain MO Dietrich, CE Mantese, LO Porciuncula, G Ghisleni, L Vinade, ... Brain research 1065 (1-2), 20-25, 2005 | 122 | 2005 |
| Coffee, caffeine, chlorogenic acid, and the purinergic system N Stefanello, RM Spanevello, S Passamonti, L Porciúncula, CD Bonan, ... Food and Chemical Toxicology 123, 298-313, 2019 | 119 | 2019 |
| Diphenyl diselenide protects rat hippocampal slices submitted to oxygen–glucose deprivation and diminishes inducible nitric oxide synthase immunocontent G Ghisleni, LO Porciuncula, H Cimarosti, JBT Rocha, CG Salbego, ... Brain research 986 (1-2), 196-199, 2003 | 115 | 2003 |
| Long‐term Effect of Convulsive Behavior on the Density of Adenosine A1 and A2A Receptors in the Rat Cerebral Cortex N Rebola, LO Porciúncula, LV Lopes, CR Oliveira, P Soares‐da‐Silva, ... Epilepsia 46, 159-165, 2005 | 110 | 2005 |
| Enriched environment effects on behavior, memory and BDNF in low and high exploratory mice V Kazlauckas, N Pagnussat, S Mioranzza, E Kalinine, F Nunes, ... Physiology & behavior 102 (5), 475-480, 2011 | 106 | 2011 |
| Anti‐nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors AP Schmidt, AE Böhmer, C Antunes, C Schallenberger, LO Porciúncula, ... British journal of pharmacology 156 (1), 163-172, 2009 | 101 | 2009 |
| Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for … AS Freitas, AS Prestes, C Wagner, JH Sudati, D Alves, LO Porciúncula, ... Molecules 15 (11), 7699-7714, 2010 | 95 | 2010 |
| Adenosine A2A receptors are necessary and sufficient to trigger memory impairment in adult mice N Pagnussat, AS Almeida, DM Marques, F Nunes, GC Chenet, ... British Journal of Pharmacology 172 (15), 3831-3845, 2015 | 87 | 2015 |
| Repeated restraint stress alters hippocampal glutamate uptake and release in the rat FU Fontella, DA Vendite, AS Tabajara, LO Porciúncula, ILS Torres, ... Neurochemical research 29, 1703-1709, 2004 | 82 | 2004 |
| Caffeine triggers behavioral and neurochemical alterations in adolescent rats AP Ardais, MF Borges, AS Rocha, C Sallaberry, RA Cunha, ... Neuroscience 270, 27-39, 2014 | 81 | 2014 |
| Effect of mercuric chloride intoxication and dimercaprol treatment on delta-aminolevulinate dehydratase from brain, liver and kidney of adult mice. T Emanuelli, JB Rocha, ME Pereira, LO Porciuncula, VM Morsch, ... Pharmacology & toxicology 79 (3), 136-143, 1996 | 80 | 1996 |
